Archives for posts with tag: y-chromosome

a linkfest! =D

Experimental evolution reveals hidden diversity in evolutionary pathways“Our findings show that parallel genetic evolution is strongly biased by constraints and we reveal the genetic bases. From such knowledge, and in instances where new phenotypes arise via gene activation, we suggest a set of principles: evolution proceeds firstly via pathways subject to negative regulation, then via promoter mutations and gene fusions, and finally via activation by intragenic gain-of-function mutations. These principles inform evolutionary forecasting and have relevance to interpreting the diverse array of mutations associated with clinically identical instances of disease in humans.”

Selectionism Strikes Back! – from razib.

Genomes carry a heavy burden“Most people’s DNA contains genetic mutations that are potentially lethal to offspring…. Most people carry one or two genetic mutations that can cause early death or infertility in their offspring….”

World’s oldest stone tools discovered in Kenya“Researchers…say they have found the oldest tools made by human ancestors — stone flakes dated to 3.3 million years ago. That’s 700,000 years older than the oldest-known tools to date, suggesting that our ancestors were crafting tools several hundred thousand years before our genus Homo arrived on the scene. If correct, the new evidence could confirm disputed claims for very early tool use, and it suggests that ancient australopithecines like the famed ‘Lucy’ may have fashioned stone tools, too.”

Neanderthals manipulated the bodies of adults and children shortly after death

Neandertal flutes debunked – @dienekes’.

IQ prediction from structural MRI – from steve hsu. see also: MRI-Based Intelligence Quotient (IQ) Estimation with Sparse Learning.

New brain science shows poor kids have smaller brains than affluent kids – see also: Credit, where credit is due, to Lyndsey Layton and Income, brain, race: Prof Kimberly Noble replies and Howitzer or Katyusha: Reply to Prof Noble at dr. james thompson’s blog. – and see also: In today’s social science, wishing makes it so – from charles murray.

Gene study may explain why some remain quick thinkers“Genetic differences could explain why some people are quicker thinkers in middle age and later life, a study of data from 30,000 people suggests.” – see also: GWAS for executive function and processing speed suggests involvement of the CADM2 gene.

Prediction of brain age suggests accelerated atrophy after traumatic brain injury – h/t stuart ritchie! who tweeted: “Super-cool new paper on how to predict someone’s age just from a brain image (r = .92!)”

National Wealth and IQ at the Edge: American Exceptionalism, East Asian Mediocrity – anatoly karlin’s “big-ass blog on national wealth, IQ, HBD, East Asians, smart fractions, etc.” (~_^)

In the beginning was the Word – dr. james thompson blogs on the recent woodley et al. paper “By their words ye shall know them: Evidence of genetic selection against general intelligence and concurrent environmental enrichment in vocabulary usage since the mid 19th century.”

Born That Way – from greg cochran.

Female Same-Sex Attraction Revisited – from jayman.

Examining the S factor in Mexican states – from emil kirkegaard.

Sex differences and vulnerability: how the male-female divide affects health“[S]ome studies have shown that premature baby girls will grow up to suffer greater language deficits than premature boys, whereas boys exposed to certain prenatal toxins will suffer greater deficits to spatial skills than girls similarly exposed, but because sex differences were never the original focus of the research no one, until Geary, has united these sex specific developmental problems and placed them in evolution’s bigger picture. Geary explains, ‘Sexually selected traits are the first to go; for example, low level exposure to prenatal toxins will affect play in boys but not their IQ: if you don’t measure the right thing you will fail to detect underlying problems.'” – h/t steve stewart williams!

Men up to five times more likely to commit sex crimes than the average male if they have brother or father convicted of a sex offence – h/t claire lehmann! who tweeted: “Survey of 21,566 men convicted of sex crimes from 1973- 2009 has revealed a strong genetic component to sex offending.” – see also: Sexual offending runs in families: A 37-year nationwide study.

Aggressive-Antisocial Boys Develop Into Physically Strong Young Men“We found that males’ antisocial tendencies temporally precede their physical formidability. Boys, but not girls, with greater antisocial tendencies in childhood attained larger increases in physical strength between the ages of 11 and 17. These results support sexual selection theory, indicating an adaptive congruence between male-typical behavioral dispositions and subsequent physical masculinization during puberty.”

Childhood Self-Control and Unemployment Throughout the Life Span: Evidence From Two British Cohort Studies“Analyzing unemployment data from two nationally representative British cohorts (N = 16,780), we found that low self-control in childhood was associated with the emergence and persistence of unemployment across four decades. On average, a 1-SD increase in self-control was associated with a reduction in the probability of unemployment of 1.4 percentage points after adjustment for intelligence, social class, and gender.”

Enlisting in the Military: The Influential Role of Genetic Factors“Given that enlistment in the U.S. military is completely voluntary, there has been a great deal of interest in identifying the various factors that might explain why some people join the military, whereas others do not. The current study expanded on this line of literature by estimating the extent to which genetic and environmental factors explained variance in the liability for lifetime participation in the military. Analysis of twin pairs drawn from the National Longitudinal Study of Adolescent to Adult Health (Add Health) revealed that 82% of the variance was the result of genetic factors, 18% of the variance was the result of nonshared environmental factors, and none of the variance was accounted for by shared environmental factors.” – from brian boutwell et al.

Risk of Suicide Among US Military Service Members Following Operation Enduring Freedom or Operation Iraqi Freedom Deployment and Separation From the US Military“Findings do not support an association between deployment and suicide mortality in this cohort. Early military separation (<4 years) and discharge that is not honorable were suicide risk factors.” – h/t michael story!

Verbal ability as a predictor of political preferences in the United States, 1974–2012“[H]igher vocabulary scores are associated with a greater likelihood that people place themselves on the ideological and political spectrum and that they vote in presidential elections, but have only small relationships with liberal-versus-conservative self-identification.”

Do our genes tell us how to vote? Study of twins says they might

On the Malleability and Plasticity of the History of the Blank Slate and 21st Century Moral Philosophy Advances Boldly into the 19th Century – from helian.

More on the younger Franz Boas – from peter frost.

Surnames and Y-Chromosomal Markers Reveal Low Relationships in Southern Spain – ruh roh.

New study finds genetic predisposition for noise-induced hearing loss

New function of obesity gene revealed

The placebome: Where genetics and the placebo effect meet

Chimps That Hunt Offer a New View on Evolution“[A] 10-year study of chimpanzees in Senegal shows females playing an unexpectedly big role in hunting and males, surprisingly, letting smaller and weaker hunters keep their prey. The results do not overturn the idea of dominant male hunters, said Jill D. Pruetz of Iowa State University, who led the study. But they may offer a new frame of reference on hunting, tools and human evolution. ‘We need to broaden our perspective,’ she said.”

Upper Palaeolithic ritualistic cannibalism at Gough’s Cave (Somerset, UK): The human remains from head to toe“Our present analysis of the postcrania has identified a far greater degree of human modification than recorded in earlier studies. We identify extensive evidence for defleshing, disarticulation, chewing, crushing of spongy bone, and the cracking of bones to extract marrow. The presence of human tooth marks on many of the postcranial bones provides incontrovertible evidence for cannibalism.”

Yes, You Can Catch Insanity“A controversial disease revives the debate about the immune system and mental illness.” – pediatric autoimmune neuropsychiatric disorders or “PANDAS”.

Hatfield and McCoy Feud — The Real Thing

Colors help set body’s internal clock“[Mice] use light’s changing color to set their own clocks, a finding that researchers expect will hold for humans, too.”

The Myth of the Angry Atheist“[T]hese results support the idea that people believe atheists are angry individuals, but they do not appear to be angrier than other individuals in reality.”

Flowers Are “Darker” at Lower Latitudes“UV radiation may explain why plants and animals closer to the equator come in darker varieties.”

The Disease That Turned Us Into Genetic-Information Junkies – brief history on tay–sachs disease research.

Antibiotic Resistant Bacteria Could Predate Antibiotics“A South American tribe, called the Yanomami, which was isolated for about 11,000 years prior to 2009, have gut bacteria that carry antibiotic resistance genes, according to new research. The Yanomami’s microbiome is far more diverse than that of Europeans or North Americans, but it also contains antibiotic resistant genes, despite never having had antibiotics. The findings suggest antibiotic resistance predates antibiotics, although it is possible the Yanomami ingested naturally occurring antibiotics in soil at some point.” – see also: The microbiome of uncontacted Amerindians.

Rotherham Worker ‘Told To Give Girls To Abusers’“The ex-protection worker says she repeatedly raised concerns about men taking girls away but her boss told her to ‘let them go’.” – also: State wards being groomed for prostitution by paedophile gangs“Organised gangs of paedophiles are grooming state wards as young as 12 for prostitution. Veteran child protection workers have told the Herald Sun they are powerless to protect the children in their care and that the sexual exploitation of state wards is ‘endemic’…. Victoria Police has set up a taskforce to investigate a gang of Afghani men in Dandenong suspected of preying on teens in care.” – australia now. =/

bonus: Jurassic Park in real life: The race to modify the DNA of endangered animals and resurrect extinct ones“Professor Church has applied a sophisticated and revolutionary ‘gene editing’ technique known as Crispr and has managed to get it working in elephant cells to carry out 14 precise changes to its genome. ‘We are now working on in vitro organogenesis [organ formation] and embryogenesis [embryo formation],’ he told The Independent in an email.”

bonus bonus: Genome Digest – findings from genomes of mountain gorilla, pseudomonas aeruginosa, canary, bird flu strain, and leprosy bacterium.

bonus bonus bonus: Through This Chemical Loop, Dogs Win Our Hearts

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Europeans drawn from three ancient “tribes”“The modern European gene pool was formed when three ancient populations mixed within the last 7,000 years, Nature journal reports. Blue-eyed, swarthy hunters mingled with brown-eyed, pale skinned farmers as the latter swept into Europe from the Near East. But another, mysterious population with Siberian affinities also contributed to the genetic landscape of the continent.” – see also: Before Slavery“From what I can see so far, it looks as the invaders killed all the LBK-descended farmers in northern Europe, or nearly so. The locals had had long trapezoidal houses clustered in small villages: the Corded Ware culture has almost no buildings at all, and a lot less agriculture. They didn’t make the EEF guys serfs and get a cut of their grain – the villages disappeared. They didn’t tax them, but then money and bureaucracy hadn’t been invented yet. Same for slavery: hadn’t been invented, probably. Judging from the mtDNA patterns, they didn’t even grab many of the nubile women. The genetic mix changes little as you move across the north European plain: if the invaders were picking up local genes as they rolled along, it should have. We used to call Corded Ware the Battle-Axe culture, but that’s too accurate for comfort.” – from greg cochran.

They weren’t wimps: how modern humans, like Neanderthals, braved the northern cold“Recent finds at Willendorf in Austria reveal that modern humans were living in cool steppe-like conditions some 43,500 years ago – and that their presence overlapped with that of Neanderthals for far longer than we thought.” – h/t mr. robert ford!

Stone Age groups made similar toolmaking breakthroughs“Different palaeolithic populations around the world might have developed a crucial toolmaking skill independently. This conclusion, based on the analysis of hundreds of artefacts from a recently excavated archaeological site in Armenia, weakens a long-held theory that Stone Age people in Eurasia learnt sophisticated techniques from migrating African tribes. The work is published in Science.”

Human paternal and maternal demographic histories: insights from high-resolution Y chromosome and mtDNA sequences“Comparisons of maternally-inherited mitochondrial DNA (mtDNA) and paternally-inherited non-recombining Y chromosome (NRY) variation have provided important insights into the impact of sex-biased processes (such as migration, residence pattern, and so on) on human genetic variation…. Our results confirm the controversial assertion that genetic differences between human populations on a global scale are bigger for the NRY than for mtDNA, although the differences are not as large as previously suggested. More importantly, we find substantial regional variation in patterns of mtDNA *versus* NRY variation.” – h/t juan fernández lópez! – see also: New analysis of human genetic history reveals female dominance – (heh. that was a nice twist on the story! (~_^) ) h/t frau katze!

23andMe mega-study on different American groups – @dienekes’. see also: The genetic ancestry of African, Latino, and European Americans across the United States.

Admixture in Latin America: Geographic Structure, Phenotypic Diversity and Self-Perception of Ancestry Based on 7,342 Individuals“We estimated individual ancestry proportions in a sample of 7,342 subjects ascertained in five countries (Brazil, Chile, Colombia, México and Perú). These individuals were also characterized for a range of physical appearance traits and for self-perception of ancestry. The geographic distribution of admixture proportions in this sample reveals extensive population structure, illustrating the continuing impact of demographic history on the genetic diversity of Latin America. Significant ancestry effects were detected for most phenotypes studied. However, ancestry generally explains only a modest proportion of total phenotypic variation. Genetically estimated and self-perceived ancestry correlate significantly, but certain physical attributes have a strong impact on self-perception and bias self-perception of ancestry relative to genetically estimated ancestry.” – see also razib: The Phenotypic and the Genotypic.

Ashkenazi Jewish population has distinctive, yet similar genomes“Post-population bottleneck, descendants of Eastern European Jews are all 30th-ish cousins…. Compared to genomes of modern Europeans—in this case, the genomes of 26 Flemish people—the Ashkenazi genomes have 47 percent more novel DNA differences per genome. These DNA variants, while novel, are population specific; sequence sharing, where two individuals have a set of the same variants, is eight percent more abundant among the Ashkenazi Jews than it is between the two populations or even among the Flemish genomes.” – h/t billare!

Why Did Civilization Lag in Africa? – from steve sailer.

Force of nature gave life its asymmetry“‘Left-handed’ electrons destroy certain organic molecules faster than their mirror versions.”

make sure not to miss jayman’s new Obesity Facts page. and give him some money, too! (^_^)

A fruitful encounter“Did the Christian doctrine of original sin create the guilt cultures of Northwest Europe? Or did the arrow of causality run the other way?” – from peter frost.

Review: G Is for Genes: The Impact of Genetics on Education and Achievement (Kathryn Asbury, Robert Plomin) – from emil kirkegaard.

The hereditarian hypothesis almost certainly true“Surely, there are huge benefits to being the first author to publish a study that almost conclusively disproves the genetic model for AA’s. Researchers with access to the data have a strong incitement to publish such a study. If the data supports the view, they have all the necessary means too. Since they haven’t published it, we can hence infer that the data does not support the politically favorable non-genetic conclusion, but instead the genetic model.” – also from emil kirkegaard.

Cognitive ability and party identity in the United States“[I]ndividuals who identify as Republican have slightly higher verbal intelligence than those who identify as Democrat…. [H]igher intelligence among classically liberal Republicans compensates for lower intelligence among socially conservative Republicans.” – the results suggest. – h/t stuart ritchie!

Lighter-skinned minorities are more likely to support Republicans

A study of the performance of Egyptian college students on the Advanced Progressive Matrices“The Egyptian raw scores were transformed to British IQ equivalents using the published 1992 British norms for the APM, on which the sample obtained a British IQ of 89.5. Science students obtained a significantly higher average mean score than arts students by 7.5 IQ points. Male students obtained a non-significantly higher average IQ than female students 1.2 IQ points. Male students had greater variability than the female students.” – h/t erwin schmidt!

The Available Pool – ed realist goes all voldemort on us. again.

Epigenetics, the Glory and the Hype“Epigenetics is real. But it doesn’t change everything. That needs to be said, because people seem to get the impression that everything is changed.” – from razib.

Human preferences for sexually dimorphic faces may be evolutionarily novel [pdf] – “A large literature proposes that preferences for exaggerated sex typicality in human faces (masculinity/femininity) reflect a long evolutionary history of sexual and social selection. This proposal implies that dimorphism was important to judgments of attractiveness and personality in ancestral environments. It is difficult to evaluate, however, because most available data come from large-scale, industrialized, urban populations. Here, we report the results for 12 populations with very diverse levels of economic development. Surprisingly, preferences for exaggerated sex-specific traits are only found in the novel, highly developed environments. Similarly, perceptions that masculine males look aggressive increase strongly with development and, specifically, urbanization.” – h/t jayman!

Do your genes skew how you taste alcohol?“A new study shows that how people perceive and taste alcohol varies as a result of genetics. The scientists focused on three chemosensory genes—two bitter-taste receptor genes known as TAS2R13 and TAS2R38 and a burn receptor gene, TRPV1. The research is the first to consider whether variation in the burn receptor gene might influence alcohol sensations, which has not previously been linked to alcohol consumption.” – alcohol tastes gooooood! (~_^) – h/t phillip melton!

Parent–Offspring Similarity for Drinking: A Longitudinal Adoption Study [pdf] – “Findings imply that genetic influences on drinking behavior increase with age while shared family environment influences decline, especially during the transition from late-adolescence to early adulthood.” – h/t emil kirkegaard!

Violent Video Games and Real-World Violence: Rhetoric Versus Data“Contrary to the claims that violent video games are linked to aggressive assaults and homicides, no evidence was found to suggest that this medium was positively related to real-world violence in the United States. Unexpectedly, many of the results were suggestive of a decrease in violent crime in response to violent video games. Possible explanations for these unforeseen findings are discussed and researchers are cautioned about generalizing the results from laboratory and correlational studies to severe forms of violent behavior.” – h/t mugwump! who tweeted some of the tables here, here, and here.

The Objective Morality Delusion“Atheists often scorn those who believe in the God Delusion. The faithful, in turn, scorn those atheists who believe in the Objective Morality Delusion. The scorn is understandable in both cases, but I give the nod to the faithful on this one….” – from helian.

Paradox of nationalism“Nationalism as we know it arose in modern times in Europe. Other countries outside Europe just don’t seem to have the same thing, although there are exceptions, such as Japan, or maybe Turkey. And in fact, nationalism was at one time considered a part of liberalism – which is another European invention…. Other countries that don’t have the same history as Europe seem unlikely to develop that kind of nationalism. Think of Iraq, Syria, most African countries, even China: they are more given to clannishness than patriotism.” – from mr. mangan, esq.

Plant breeding, not working slaves harder, drove cotton efficiency gains in the US South – from pseudoerasmus.

Confusion Over the Biological Reality of the Human Races“[O]ne can see clearly why Wade’s argument is not racist: at the core of his argument is his claim that the tribalism of racial ethnocentrism belongs to an ancient stage of human evolution that has to be overcome to move into modern states and inclusive institutions (see Wade, 136, 173-82, 196-97).” – larry arnhart on A Troublesome Inheritance.

Yes, it’s official, men are from Mars and women from Venus, and here’s the science to prove it“In his fascinating new book the developmental biologist Lewis Wolpert argues that there is actually hard science behind many of our stereotypical gender roles.” – h/t claire lehmann!

The Woman’s Heart Attack“[M]en more typically have ‘crushing’ pain; women, nausea. That women are likelier to have early warning signs, such as unaccustomed fatigue or insomnia (unaccustomed: That’s the key word here). That we are likelier — this spooked me and kept me, for months, glued to calendars — to die within a year of a heart attack. That our symptoms can be so varied and nuanced that we feel no fear, seek no help, and possibly die — which may be why, although more men have heart attacks, a greater percentage of women die of them.”

The Evolution of Culturally-Variable Sex Differences: Men and Women Are Not Always Different, but When They Are…It Appears *Not* to Result from Patriarchy or Sex Role Socialization“[E]vidence is marshaled across 21 data sources that directly challenge this foundational assumption of social role theory. Empirically, sex differences in most psychological traits — in personality, sexuality, attitudes, emotions, behaviors, and cognitive abilities — are conspicuously *larger* in cultures with more egalitarian sex role socialization and greater sociopolitical gender equity. Even sex differences in many physical traits such as height, obesity, and blood pressure are larger in cultures with more egalitarian sex role socialization and greater sociopolitical gender equity.”

School Performance After Preterm Birth“An increased risk of poor school performance for children born preterm has been shown in many studies, but whether this increase is attributable to preterm birth per se or to other factors associated with preterm birth has not been resolved…. Preterm birth was strongly and negatively correlated with school performance. The distribution of school grades for children born at 31-33 weeks was on average 3.85 (95% confidence interval = -4.36 to -3.35) centiles lower than for children born at 40 weeks. For births at 22-24 weeks, the corresponding figure was -23.15 (-30.32 to -15.97). When taking confounders into account, the association remained. When restricting the analysis to siblings, however, the association between school performance and preterm birth after week 30 vanished completely, whereas it remained, less pronounced, for preterm birth before 30 weeks of gestation. Our study suggests that the association between school performance and preterm birth after 30 gestational weeks is attributable to factors other than preterm birth per se.”

Are Neighborhood Health Associations Causal? A 10-Year Prospective Cohort Study With Repeated Measurements – h/t amir sariaslan! who tweeted: “Neighborhoods did not cause health outcomes in Australian large longitudinal within-individual study over 10 years.”

Seat of Selflessness Found in Brains of Extreme Altruists“In this case researchers chose to study people who donated a kidney to a complete stranger. They found that not only are extreme altruists’ brains different from a normal person’s, they’re basically the opposite of a psychopath’s in one key way – indicating that a specific brain region may play an important role in people’s ability to care for one another.” – n=39, but it’s a start!

Can the Game of Thrones option save the UK?“The situation now resembles the Union of Crowns from 1603-1707 when Scotland had its own parliament but was still under the king in Westminster, and Cameron is behaving like Charles I: making promises to his northern kingdom that affect the southern one, without regards to how the southerners feel. Just as in 1640, the greatest protests are coming from the east of England, once the stronghold of Puritanism and the parliamentary rebels and now the Ukip heartland.” – from ed west.

God, Darwin and My College Biology Class“[A] third consequence of evolutionary insights: a powerful critique of theodicy, the scholarly effort to reconcile belief in an omnipresent, omni-benevolent God with the fact of unmerited suffering. Theological answers range from claiming that suffering provides the option of free will to announcing (as in the Book of Job) that God is so great and we so insignificant that we have no right to ask. But just a smidgen of biological insight makes it clear that, although the natural world can be marvelous, it is also filled with ethical horrors: predation, parasitism, fratricide, infanticide, disease, pain, old age and death — and that suffering (like joy) is built into the nature of things. The more we know of evolution, the more unavoidable is the conclusion that living things, including human beings, are produced by a natural, totally amoral process, with no indication of a benevolent, controlling creator.” – david barash, pessimist(?).

Incest a “fundamental right” says German committee says“Anti-incest laws in Germany could be scrapped after a government-backed group said relationships between brothers and sisters should be legal.” – those wacky germans! h/t anatoly!

Radicalised Muslims in UK more likely to be born in Britain, rich and depressed“Young British Muslims whose families have lived in the UK for generations are more at risk of radicalisation than recent migrants to Britain, according to new research which reveals the common characteristics of those most vulnerable to recruitment by terrorists.” – we’ve seen that pattern before. h/t ed west!

Millions of Old Tyres are Dumped Near Empty Apartment Blocks in Spanish Ghost Town – you HAVE to see the photos! h/t ian geldard!

bonus: Skin coloring of rhesus macaque monkeys linked to breeding success, new study shows

bonus bonus: Fantastically Wrong: Europe’s Insane History of Putting Animals on Trial and Executing Them – h/t kyle hill!

bonus bonus bonus: Belgium to build beer pipeline under Bruges – those wacky belgians!

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‘Rare’ Gene Common in African Descendants, May Contribute to Heart Disease“Researchers at Weill Cornell Medical College have found that a genetic variation that is linked to increased levels of triglycerides — fats in the blood associated with disorders such as heart disease, type 2 diabetes, obesity and stroke — is far more common than previously believed and disproportionally affects people of African ancestry…. The finding offers a clue as to why Africans and people of African descent have an increased risk of cardiovascular disease and type 2 diabetes compared to many other populations, says the study’s senior author, Dr. Ronald Crystal, chairman of genetic medicine at Weill Cornell. African Americans with the variant had, on average, 52 percent higher triglyceride levels compared with blacks in the study who did not have the variant…. The gene variant the scientists studied is a single point mutation — a replacement of one of DNA segment with another — in the ApoE gene, which carries fats and other molecules through the blood.” – h/t hbd bibliography!

A gene mutation for excessive alcohol drinking found“UK researchers have discovered a gene that regulates alcohol consumption and when faulty can cause excessive drinking…. [M]ice with a genetic mutation to the gene Gabrb1 overwhelmingly preferred drinking alcohol over water, choosing to consume almost 85% of their daily fluid as drinks containing alcohol…. Dr Quentin Anstee, Consultant Hepatologist at Newcastle University, joint lead author said: ‘It’s amazing to think that a small change in the code for just one gene can have such profound effects on complex behaviours like alcohol consumption.’ – see also Firewater from greg cochran.

Predicting Human Body Height from DNA“Predicting tall stature from these 180 DNA variants resulted in an accuracy of 0.75 on a scale from 0.5 (meaning random prediction) to 1.0 (completely accurate prediction). ‘Although the achieved DNA-based prediction accuracy for tall stature is still somewhat lower than we previously established for eye color, hair color and age,’ said Kayser, ‘I expect that upcoming new knowledge on height genetics will further increase the accuracy in predicting tall stature, and eventually the full range of body height, from DNA.'”

Study Connects Dots Between Genes, Human Behavior“The team studied individuals with a rare disorder known as Williams syndrome. By measuring neural activity in the brain associated with the distinct language skills and facial recognition abilities that are typical of the syndrome, they showed that Williams is due not to a single gene but to distinct subsets of genes, hinting that the syndrome is more complex than originally thought.”

Different Gene Expression in Male, Female Brains May Help Explain Brain Disorder Differences“UCL scientists have shown that there are widespread differences in how genes, the basic building blocks of the human body, are expressed in men and women’s brains. Based on post-mortem adult human brain and spinal cord samples from over 100 individuals, scientists at the UCL Institute of Neurology were able to study the expression of every gene in 12 brain regions…. They found that the way that the genes are expressed in the brains of men and women were different in all major brain regions and these differences involved 2.5% of all the genes expressed in the brain.” – h/t heartiste!

Only two genes maketh the man…or mouse“The defining genetic feature of maleness, the Y chromosome, contains only two genes that are absolutely essential for male function – at least in mice.” – “male function” = producing sperm, apparently. and taking out the garbage of course. (~_^)

Male facial masculinity as a cue to health outcomes“Although both attractiveness and rated health were associated with better actual health in the past and future (mainly indexed by lower antibiotic use), results were mixed for masculinity. With respect to respiratory illnesses, facial masculinity (assessed using morphometric techniques) was associated with better past health but with worse future health.” – h/t hbd bibliography!

HPV: Sex, cancer and a virus“Human papillomavirus is causing a new form of head and neck cancer — leaving researchers scrambling to understand risk factors, tests and treatments.” – h/t john durant!

Gut bacteria could make cancer treatments more effective, researchers find“[M]ice with reduced levels of bacteria in their gut were less responsive to treatments than mice that had a normal microbiota.”

When We Lose Antibiotics, Here’s Everything Else We’ll Lose Too – *gulp* =/

Arroyo del Vizcaíno, Uruguay: a fossil-rich 30-ka-old megafaunal locality with cut-marked bones – evidence for humans in uruguay 30,000 years ago? hunting giant sloths?

Who Built Serpent Mound? – dunno.

Sexual selection on the American frontier – re. nineteenth century mormons – from jason collins.

Jealousy in a small-scale, natural fertility population: the roles of paternity, investment and love in jealous response – jealousy rates in a non-w.e.i.r.d. population (the himba of namibia) – “In this population, the majority of both men and women report greater distress over a sexual infidelity, with men reaching an almost unanimous consensus (96%). Despite the skew for both men and women, there is a significant sex difference in the direction predicted by the evolutionary hypothesis….” – h/t andrew badenoch!

Study examines potential evolutionary role of ‘sexual regret’ in human survival and reproduction“[The results] suggest that men are more likely to regret not taking action on a potential liaison, and women are more remorseful for engaging in one-time liaisons.”

A Hot Wife Means A Happier Marriage“[M]en are happier with attractive women and women don’t care as much about men’s looks. Stop the goddamned presses! You mean men and women are…*GASP*…different?” – @chateau heartiste. (^_^) – original research article.

Oxytocin leads to monogamy: Hormone stimulates the brain reward system when viewing the partnerthe luuuuuuuuv hormone! (^_^)

Promiscuous mouse moms bear sexier sons“Males make more pheromone if mama had access to many mates”

We can’t ignore the evidence: genes affect social mobility“Why do so many people fail to accept the overwhelming evidence that genes contribute to academic achievement and thereby social status?” – h/t ed west!

The Sour Grapes of Pisa – from staffan.

The envirome and the connectome: exploring the structural noise in the human brain associated with socioeconomic deprivation – from neuroskeptic: “People from deprived parts of Glasgow have brains that are more ‘random’ structurally than those from rich areas.” – and from jayman: “Of course IQ has nothing to do with it… ;)”

Poor people’s poor sense – from the awesome epigone.

Meat, egg and dairy nutrient essential for brain development“Asparagine, found in foods such as meat, eggs, and dairy products, was until now considered non-essential because it is produced naturally by the body. Researchers at the University of Montreal and its affiliated CHU Sainte-Justine Hospital found that the amino acid is essential for normal brain development. This is not the case for other organs.”

Different rates of first admissions for psychosis in migrant groups in Paris“Our findings suggest that Sub-Saharan migrants were identified as the most vulnerable migrant group for developing psychosis in France, but additional work is warranted to confirm these trends.” – h/t neuroskeptic! – see also Redneck Psychiatrists from greg cochran.

Nations of Canada – from jayman.

Another Look at ‘The Rise of the West’ – But With Better Numbers“The North Sea begins to diverge from the rest of Europe long before the ‘West’ begins its more famous split from ‘the rest….’ [W]e can pin point the beginning of this ‘little divergence’ with greater detail. In 1348 Holland’s GDP per capita was $876. England’s was $777. In less than 60 years time Holland’s jumps to $1,245 and England’s to 1090. The North Sea’s revolutionary divergence started at this time.” – from t.greer.

When it comes to diversity, most of us vote with our feet“Liberals are almost as likely to flee diversity as conservatives, according to new research by Prof Eric Kaufmann for Demos. Some 61 per cent of white people who were ‘very comfortable’ with mixed marriages (the best indicator of views on race) moved to whiter areas during the period, compared to 64 per cent of those who were ‘fairly uncomfortable’.” – from “utterly sh** in every way” ed west.

Race, Race, Race, Race, Race, Race, Race, Race, Race“*Race is real*. In aggregate, human populations *differ*. Because of those differences, their interests can differ, too — and that can lead to various kinds of unpleasantness. Birds of a feather, whether we approve or not, still tend to flock together.” – from malcolm pollack.

How to have a sensible conversation about immigration“The poor of the world are on the move, eager to live and work in rich nations. What are the consequences? Talking about them cannot be a taboo.” – h/t steve sailer!

3 Reasons Diversity Isn’t Working – @theden.

How Britain became ashamed of being Great: Major new book argues liberal self-loathing threatens the values that define our nation – a MUST READ from daniel hannan! buy the book, too: How We Invented Freedom & Why It Matters.

Study: Having daughters makes parents more likely to be Republican – i thought it was democrats? – and on that note: Does Having Sisters Make You Conservative? – h/t avi tuschman!

Atheists get sweaty when daring God“When you get anxious or emotionally aroused, you sweat. Not a lot, but enough to be detected using electrodes on the finger tips. And it turns out that if you take a bunch of atheists, and get them to dare god to do horrible things, they get sweaty.” – heh! (really small sample size, tho.) – h/t anatoly!

The brains of high functioning autistic individuals do not synchronize with those of others“Our ISC [InterSubject Correlations-ISCs] results suggest that the minds of ASD individuals do not ‘tick together’ with others while perceiving identical dynamic social interactions.” – no kidding?! (~_^)

Cleansing the scientific literature – from peter frost. see also Danish Progress in Suppressing Thoughtcrime from helian.

In Israel, a Push to Screen for Cancer Gene Leaves Many Conflicted“The country has one of the highest rates of breast cancer in the world, according to a World Health Organization report. And some leading scientists here are advocating what may be the first national screening campaign to test women for cancer-causing genetic mutations common among Jews — tests that are already forcing young women to make agonizing choices about what they want to know, when they want to know it and what to do with the information.”

The Neuroscientist Who Discovered He Was a Psychopath – h/t naturalismo!

10,000-year-old house uncovered outside Jerusalem“‘Here we have evidence of man’s transition to permanent dwellings'” – cool!

Here’s why wine snobs should probably be called bacteria snobs“Differences in wine quality between vineyards have long been attributed to processing techniques and seasonal variation. But research now suggests that regional differences between wines are shaped by microbes — specifically, fungi and bacteria. Cultivating certain grape microbes may actually improve wine flavor.”

bonus: FDA may begin seizing [23andMe] home DNA testing kits – losers. (the fda, i mean.)

bonus bonus: Do We Live in the Matrix? – yes.

bonus bonus bonus: Economics of Violence: What would it cost you if you didn’t fight back?“In my 30 years of researching violence, every victim of violence who lived to tell the tale said they had a ‘bad feeling’ before the actual attack…. If an alarm goes off, respond to it. Got a bad feeling? Address it. Something nagging at you? Stop and look into it. Don’t ignore these signals. Don’t rationalize and mentally correct them. Don’t dismiss them without assessing them. Your body is built for survival and one of its hard-wired systems is designed to alert you to danger.” – h/t mr. mangan, esq!

bonus bonus bonus bonus: Sexual violence in gang neighbourhoods [in the u.k] is ‘like that in war zones’ with girls as young as 11 being groomed and raped” – =/

bonus bonus bonus bonus bonus: Latest restaurant receipt hoax – from chuck @gucci little piggy.

bonus bonus bonus bonus bonus bonus: Banks Warn Fed They May Have To Start Charging Depositors – =/ – h/t charles!

bonus bonus bonus bonus bonus bonus bonus: Over 50,000 illegal Ethiopian workers sent home from Saudi Arabia

bonus bonus bonus bonus bonus bonus bonus bonus: Fabulous example of helpful Muslims in the UK: solving local blood feud – terrific. =/ – from frau katze.

bonus bonus bonus bonus bonus bonus bonus bonus bonus: China’s rich fleeing the country — with their fortunes – h/t randall parker! – also: China’s villages vanish amind rush for the cities.

bonus bonus bonus bonus bonus bonus bonus bonus bonus bonus: Man sells testicle so he can buy a Nissan 370Z – (o_O)

bonus bonus bonus bonus bonus bonus bonus bonus bonus bonus bonus: We’d rather eat turkey“Thanksgiving is that very special holiday when we take a break from our hectic everyday lives to spend quality time with our loved ones, rediscovering all the reasons why we don’t actually live with them.” – (~_^) – from dave barry.

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New data reveal extent of genetic overlap between major mental disordersgwas study**: “[T]he overlap was highest between schizophrenia and bipolar disorder; moderate for bipolar disorder and depression and for ADHD and depression; and low between schizophrenia and autism. Overall, common genetic variation accounted for 17-28 percent of risk for the illnesses.” (**that’s redundant, isn’t it? sorry.)

Common genes may underlie alcohol dependence, eating disorders“In a study of nearly 6,000 adult twins, researchers found that common genetic factors seemed to underlie both alcoholism and certain eating disorder symptoms—namely, binge eating and purging habits, such as self-induced vomiting or laxative abuse. Genes appeared to explain 38 percent to 53 percent of the risk of developing those disorders.”

Multiple Genes Manage How People Taste Sweeteners

As Humans Change Landscape, Brains of Some Animals Change, Too“A new study suggests that the brains of several small mammals, including those of the little brown bat, have grown bigger as humans have altered the animals’ living conditions.” – ruh roh.

African genes tracked back“[The researchers] saw signs reflecting two waves of migration: one about 3,000 years ago, of non-Africans entering east Africa, and a second one 900–1,800 years ago, as east Africans migrated to southern Africa and brought non-African genes along with them…. Because of this two-step migration, some Khoe-San groups who were thought to have been genetically quite isolated actually carry 1–5% non-African DNA….”

Study Says Oldest Known Human Y-Chromosome Branch Dates to 338,000 Years Ago – h/t michael anissimov!

Genetic Research Suggests Indian Caste System Began 1,900 Years Ago – h/t david pinsen! – and speaking of castes: Caste outside of India: black blacksmiths from steve sailer.

Handaxe design reveals distinct Neanderthal cultures“Two cultural traditions existed among Neanderthals living in what is now northern Europe between 115,000 to 35,000 years ago…. [T]wo separate handaxe traditions or designs existed – one in a region now spanning south-western France and Britain – the other in Germany and further to the East.”

The Behavioral Ecology of Chimpanzee War and Liberal Peace“[V]iolent aggression among humans and chimps is a flexible natural propensity that tends to be stronger in males than in females, and the expression of that propensity depends on the social circumstances that determine the relative costs and benefits of violent fighting.” – @darwinian conservatism.

Breast feeding, intelligence, and confounded researchers – from dr. james thompson.

Two Failures to Replicate High-Performance-Goal Priming Effects

Babies learn words before birth“Brain responses suggest infants can distinguish distinct sounds from altered versions.”

Women and eye color“There is…a sex difference, with women having a more diverse palette of eye colors.” – from peter frost.

Are atheists mentally ill? – via mr. mangan, esq.

How Personality Affects Fertility: Men’s and Women’s Personalities Linked to Likelihood That They Will Have Children“Men with neurotic personality traits are having fewer children compared to previous generations…. It also found that men who are extraverted and open tend to have more children, while women who rank as conscientious on personality tests tend to have fewer children, although these findings were constant across generations.” – study done in norway. – via hbd bibliography.

Human brains are hardwired for empathy, friendship, study shows

Kinship or Citizenship? – steve sailer reviews mark weiner‘s The Rule of the Clan.

There is no hope of democracy in the Middle East“Most people, in other times and other places, have lived in societies more like Game of Thrones than Borgen, clannish rather than democratic, where people feel their loyalty and duty is towards other members of their extended family or religious community. To get people to work in the best interests of strangers so that you accept their authority when they get more people into the polling booth than you, is an achievement, not a natural state…. Egypt is an ancient civilisation but it is a clannish society….” – from ed west. (^_^) see also: Ed West interview: debating the ‘illusions’ of a diverse society.

Whence Afro criminality? – @thosewhocansee.

Steven Pinker, Science, and “Scientism”“In reality, the issue here is not whether this imaginary ‘science’ object exists and, assuming it does, whether it is ‘good’ or ‘evil.’ It is about whether we should be empowered to learn things about the universe in which we live or not. The opponents of ‘scientism’ typically rail against such things as eugenics, Social Darwinism, and the atomic bomb. These are supposedly the creations of the ‘science’ object. But, in fact, they are no such thing.” – really good stuff @helian unbound. via hbd bibliography. also from h.u. (he’s on a roll this week): Of Ingroups, Outgroups and Ideology.

The Arab Spring has failed because constitutional democracy needs nation-states – via ed west. see also: Egyptian Mirages from thomas sowell – “However widespread the desire to be free, it is wholly different from a desire to live in a society where others are free.” – yup.

How the light gets out – re. consciousness: “…the attention schema theory. It says that awareness is not something magical that emerges from the functioning of the brain. When you look at the colour blue, for example, your brain doesn’t generate a subjective experience of blue. Instead, it acts as a computational device. It computes a description, then attributes an experience of blue to itself. The process is all descriptions and conclusions and computations. Subjective experience, in the theory, is something like a myth that the brain tells itself. The brain *insists* that it has subjective experience because, when it accesses its inner data, it finds that information.”

Notes from Beijing: About That Chinese Social Contract“The traditional Chinese social contract was not a compact between individuals and the state, but a compact between Chinese society as a whole and the state…. Self interested calculations of rational individuals coolly weighing their economic and political interests never really seemed to be part of the program.” – from t. greer.

Fragile and Dangerous – Men with Borderline Personality Disorder – from staffan.

23 Signs You’re Secretly An Introvert – 20 out of 23. (*^_^*) (no way i could give a talk to an audience of 500. No. Way.) – classic link: Caring for Your Introvert.

Genomic Differences Found in Types of Cervical Cancer“…the spectrum of cancer-related gene mutations in the two main subtypes of cervical cancer — adenocarcinoma and squamous cell carcinoma. In tests on 80 cervical tumor samples, the investigators found high rates of mutations in two genes: PIK3CA and KRAS. While PIK3CA mutations appeared in both subtypes, KRAS mutations were found only in adenocarcinomas.”

US behavioural research studies skew positive“US behavioural researchers have been handed a dubious distinction — they are more likely than their colleagues in other parts of the world to exaggerate findings, according to a study published today.”

Neolithic chefs spiced their food“Mineral grains from garlic-mustard seeds found in 6,000-year-old cooking pots.” – mmmmmmm!

Denmark’s historic claim to the Faroes in doubt as archaeologists find proof that islands were inhabited before arrival of first Norse colonists“Discovery indicates existence of sea-faring northern Europeans before Vikings.”

bonus: Birds know road speed limits“Crows, house sparrows and other species judge when to flee the asphalt by average traffic rates rather than an oncoming car’s speed.”

bonus bonus: Beetles eat greedy offspring Edinburgh University research finds“Burying beetles occasionally punish young who nag for food by eating those who pester them most…. It encourages the larvae to plead more honestly according to how hungry they are and not try to outdo their siblings by pestering their mother for food.” – so there!

bonus bonus bonus: Saudi Arabia’s War on Witchcraft“A special unit of the religious police pursues magical crime aggressively, and the convicted face death sentences.”

bonus bonus bonus bonus: Bacteria can cause pain on their own“Microbes caused discomfort in mice by activating nervous system, not immune response.”

bonus bonus bonus bonus bonus: World’s first pocket calculator goes up for auction: ‘Exceptionally rare’ 17th century machine made of wood could fetch £100,000

bonus bonus bonus bonus bonus bonus: Oldest globe to depict the New World may have been discovered

bonus bonus bonus bonus bonus bonus bonus: An update to Maslow’s hierarchy of needs

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greg cochran says (or writes, i guess — unless he talks to his computer monitor like some of us people do…):

“If a new environment favored lower (or higher) aggressiveness in males, a Y-chromosome that induced lower (or higher) aggressiveness would take off. And since different Y chromosomes do indeed affect the level of aggressiveness in mice [which I just found out], possibly by affecting testosterone production – this mechanism is plausible….

“Fortunately for all concerned, the selective value of aggressiveness, etc. has been the same for all human populations forever and ever, before and after the development of agriculture. Otherwise you might see weirdly rapid expansions of particular Y-chromosome haplogroups – common, yet only a few thousand years old.”

i nominate as one such example of this selection that never happened the “YCAII=22-22 and DYS388≥15” cluster of haplogroup J-M267 which, depending on who you read, may or may not be related to the arabs’ expansion out of their peninsula in historic times. whatever the full story, haplogroup J-M267 certainly looks arab-expansiony:

HG_J1_(ADN-Y)

hage and marck have shown how mating patterns can affect the distribution of sex chromosome haplogroups (mmmm-hmmm!). the prevalence of father’s brother’s daughter’s (fbd) marriage amongst the arabs could certainly have had an effect on the successful distribution of the J-M267 haplogroup, especially the YCAII-whatchamacallit cluster mentioned above if it was really connected to the arab expansion.

remember that fbd marriage concentrates y-chromosome types into these patrilineages, so fathers, sons, grandfathers, paternal uncles, paternal nephews, paternal male cousins, etc., all share the same y-chromosome (barring variations due to mutations, of course):

parallel cousin marriage

of particular interest is how men (“C” in diagram above) ensure that their male grandchildren by their daughters (“E” in diagram above) also have their y-chromosome, ’cause they marry their daughters off to their paternal nephews (i talked about that here). this doesn’t happen in most marriage systems. so, really, ALL the males in (ideal) arab, fbd patrilineages share the same y-chromosome.

this is one way that inbreeding could serve to accelerate the acquisition of “genes for altruism” in a population. if, say, those genes were aggression genes on the y-chromosome — genes that led to altruistic behaviors in the sense that the individuals having them were more likely to “kill thy unrelated neighbor” and make life better for themselves and their own — then inbreeding, especially father’s brother’s daughter’s marriage, could help those genes pile up more quickly.

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c’mon guys! ur disappointing me here!

results from a 2008 gss question:

“does mom’s gene decide baby’s sex?” (hint. another hint.)

*facepalm*

see also here.

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