Archives for posts with tag: the brain

a linkfest! =D

Experimental evolution reveals hidden diversity in evolutionary pathways“Our findings show that parallel genetic evolution is strongly biased by constraints and we reveal the genetic bases. From such knowledge, and in instances where new phenotypes arise via gene activation, we suggest a set of principles: evolution proceeds firstly via pathways subject to negative regulation, then via promoter mutations and gene fusions, and finally via activation by intragenic gain-of-function mutations. These principles inform evolutionary forecasting and have relevance to interpreting the diverse array of mutations associated with clinically identical instances of disease in humans.”

Selectionism Strikes Back! – from razib.

Genomes carry a heavy burden“Most people’s DNA contains genetic mutations that are potentially lethal to offspring…. Most people carry one or two genetic mutations that can cause early death or infertility in their offspring….”

World’s oldest stone tools discovered in Kenya“Researchers…say they have found the oldest tools made by human ancestors — stone flakes dated to 3.3 million years ago. That’s 700,000 years older than the oldest-known tools to date, suggesting that our ancestors were crafting tools several hundred thousand years before our genus Homo arrived on the scene. If correct, the new evidence could confirm disputed claims for very early tool use, and it suggests that ancient australopithecines like the famed ‘Lucy’ may have fashioned stone tools, too.”

Neanderthals manipulated the bodies of adults and children shortly after death

Neandertal flutes debunked – @dienekes’.

IQ prediction from structural MRI – from steve hsu. see also: MRI-Based Intelligence Quotient (IQ) Estimation with Sparse Learning.

New brain science shows poor kids have smaller brains than affluent kids – see also: Credit, where credit is due, to Lyndsey Layton and Income, brain, race: Prof Kimberly Noble replies and Howitzer or Katyusha: Reply to Prof Noble at dr. james thompson’s blog. – and see also: In today’s social science, wishing makes it so – from charles murray.

Gene study may explain why some remain quick thinkers“Genetic differences could explain why some people are quicker thinkers in middle age and later life, a study of data from 30,000 people suggests.” – see also: GWAS for executive function and processing speed suggests involvement of the CADM2 gene.

Prediction of brain age suggests accelerated atrophy after traumatic brain injury – h/t stuart ritchie! who tweeted: “Super-cool new paper on how to predict someone’s age just from a brain image (r = .92!)”

National Wealth and IQ at the Edge: American Exceptionalism, East Asian Mediocrity – anatoly karlin’s “big-ass blog on national wealth, IQ, HBD, East Asians, smart fractions, etc.” (~_^)

In the beginning was the Word – dr. james thompson blogs on the recent woodley et al. paper “By their words ye shall know them: Evidence of genetic selection against general intelligence and concurrent environmental enrichment in vocabulary usage since the mid 19th century.”

Born That Way – from greg cochran.

Female Same-Sex Attraction Revisited – from jayman.

Examining the S factor in Mexican states – from emil kirkegaard.

Sex differences and vulnerability: how the male-female divide affects health“[S]ome studies have shown that premature baby girls will grow up to suffer greater language deficits than premature boys, whereas boys exposed to certain prenatal toxins will suffer greater deficits to spatial skills than girls similarly exposed, but because sex differences were never the original focus of the research no one, until Geary, has united these sex specific developmental problems and placed them in evolution’s bigger picture. Geary explains, ‘Sexually selected traits are the first to go; for example, low level exposure to prenatal toxins will affect play in boys but not their IQ: if you don’t measure the right thing you will fail to detect underlying problems.'” – h/t steve stewart williams!

Men up to five times more likely to commit sex crimes than the average male if they have brother or father convicted of a sex offence – h/t claire lehmann! who tweeted: “Survey of 21,566 men convicted of sex crimes from 1973- 2009 has revealed a strong genetic component to sex offending.” – see also: Sexual offending runs in families: A 37-year nationwide study.

Aggressive-Antisocial Boys Develop Into Physically Strong Young Men“We found that males’ antisocial tendencies temporally precede their physical formidability. Boys, but not girls, with greater antisocial tendencies in childhood attained larger increases in physical strength between the ages of 11 and 17. These results support sexual selection theory, indicating an adaptive congruence between male-typical behavioral dispositions and subsequent physical masculinization during puberty.”

Childhood Self-Control and Unemployment Throughout the Life Span: Evidence From Two British Cohort Studies“Analyzing unemployment data from two nationally representative British cohorts (N = 16,780), we found that low self-control in childhood was associated with the emergence and persistence of unemployment across four decades. On average, a 1-SD increase in self-control was associated with a reduction in the probability of unemployment of 1.4 percentage points after adjustment for intelligence, social class, and gender.”

Enlisting in the Military: The Influential Role of Genetic Factors“Given that enlistment in the U.S. military is completely voluntary, there has been a great deal of interest in identifying the various factors that might explain why some people join the military, whereas others do not. The current study expanded on this line of literature by estimating the extent to which genetic and environmental factors explained variance in the liability for lifetime participation in the military. Analysis of twin pairs drawn from the National Longitudinal Study of Adolescent to Adult Health (Add Health) revealed that 82% of the variance was the result of genetic factors, 18% of the variance was the result of nonshared environmental factors, and none of the variance was accounted for by shared environmental factors.” – from brian boutwell et al.

Risk of Suicide Among US Military Service Members Following Operation Enduring Freedom or Operation Iraqi Freedom Deployment and Separation From the US Military“Findings do not support an association between deployment and suicide mortality in this cohort. Early military separation (<4 years) and discharge that is not honorable were suicide risk factors.” – h/t michael story!

Verbal ability as a predictor of political preferences in the United States, 1974–2012“[H]igher vocabulary scores are associated with a greater likelihood that people place themselves on the ideological and political spectrum and that they vote in presidential elections, but have only small relationships with liberal-versus-conservative self-identification.”

Do our genes tell us how to vote? Study of twins says they might

On the Malleability and Plasticity of the History of the Blank Slate and 21st Century Moral Philosophy Advances Boldly into the 19th Century – from helian.

More on the younger Franz Boas – from peter frost.

Surnames and Y-Chromosomal Markers Reveal Low Relationships in Southern Spain – ruh roh.

New study finds genetic predisposition for noise-induced hearing loss

New function of obesity gene revealed

The placebome: Where genetics and the placebo effect meet

Chimps That Hunt Offer a New View on Evolution“[A] 10-year study of chimpanzees in Senegal shows females playing an unexpectedly big role in hunting and males, surprisingly, letting smaller and weaker hunters keep their prey. The results do not overturn the idea of dominant male hunters, said Jill D. Pruetz of Iowa State University, who led the study. But they may offer a new frame of reference on hunting, tools and human evolution. ‘We need to broaden our perspective,’ she said.”

Upper Palaeolithic ritualistic cannibalism at Gough’s Cave (Somerset, UK): The human remains from head to toe“Our present analysis of the postcrania has identified a far greater degree of human modification than recorded in earlier studies. We identify extensive evidence for defleshing, disarticulation, chewing, crushing of spongy bone, and the cracking of bones to extract marrow. The presence of human tooth marks on many of the postcranial bones provides incontrovertible evidence for cannibalism.”

Yes, You Can Catch Insanity“A controversial disease revives the debate about the immune system and mental illness.” – pediatric autoimmune neuropsychiatric disorders or “PANDAS”.

Hatfield and McCoy Feud — The Real Thing

Colors help set body’s internal clock“[Mice] use light’s changing color to set their own clocks, a finding that researchers expect will hold for humans, too.”

The Myth of the Angry Atheist“[T]hese results support the idea that people believe atheists are angry individuals, but they do not appear to be angrier than other individuals in reality.”

Flowers Are “Darker” at Lower Latitudes“UV radiation may explain why plants and animals closer to the equator come in darker varieties.”

The Disease That Turned Us Into Genetic-Information Junkies – brief history on tay–sachs disease research.

Antibiotic Resistant Bacteria Could Predate Antibiotics“A South American tribe, called the Yanomami, which was isolated for about 11,000 years prior to 2009, have gut bacteria that carry antibiotic resistance genes, according to new research. The Yanomami’s microbiome is far more diverse than that of Europeans or North Americans, but it also contains antibiotic resistant genes, despite never having had antibiotics. The findings suggest antibiotic resistance predates antibiotics, although it is possible the Yanomami ingested naturally occurring antibiotics in soil at some point.” – see also: The microbiome of uncontacted Amerindians.

Rotherham Worker ‘Told To Give Girls To Abusers’“The ex-protection worker says she repeatedly raised concerns about men taking girls away but her boss told her to ‘let them go’.” – also: State wards being groomed for prostitution by paedophile gangs“Organised gangs of paedophiles are grooming state wards as young as 12 for prostitution. Veteran child protection workers have told the Herald Sun they are powerless to protect the children in their care and that the sexual exploitation of state wards is ‘endemic’…. Victoria Police has set up a taskforce to investigate a gang of Afghani men in Dandenong suspected of preying on teens in care.” – australia now. =/

bonus: Jurassic Park in real life: The race to modify the DNA of endangered animals and resurrect extinct ones“Professor Church has applied a sophisticated and revolutionary ‘gene editing’ technique known as Crispr and has managed to get it working in elephant cells to carry out 14 precise changes to its genome. ‘We are now working on in vitro organogenesis [organ formation] and embryogenesis [embryo formation],’ he told The Independent in an email.”

bonus bonus: Genome Digest – findings from genomes of mountain gorilla, pseudomonas aeruginosa, canary, bird flu strain, and leprosy bacterium.

bonus bonus bonus: Through This Chemical Loop, Dogs Win Our Hearts

(note: comments do not require an email. woof?)

Stone Age skull from Kenya reveals astonishing human diversity“A partial human skull found at a site in Kenya suggests early humans living in Africa were incredibly diverse. The 22,000-year-old skull is not a new species and is clearly that of an anatomically modern human, but is markedly different from similar finds from Africa and Europe from the same time, the researchers said…. [T]he new findings suggest that during this early period of human history, Africa may have supported even greater human diversity, with small, offshoot lineages that no longer exist today….”

A New Theory on How Neanderthal DNA Spread in Asia“Researchers have discovered that Neanderthals interbred with the ancestors of Asians at two points in history, giving this population an extra infusion of Neanderthal DNA.”

Division of labor by sex and age in Neandertals: an approach through the study of activity-related dental wear“The study reveals that all individuals have cultural striations, but those detected on the adult females are longer than the striations found in adult males. Regarding the distribution of dental chipping, the prevalence of this trait is higher in the maxillary dentition of males whereas females have the majority of dental chipping on their mandibular teeth. T he differences detected on the overall activity-related dental wear pattern denote a difference or a division of labor by age and sex in Neandertals while using the mouth as a third hand, i.e., in activities other than the provisioning of food, and provide new evidence for the lifestyle of this Pleistocene fossil human species.” – h/t paleogenomics!

European languages linked to migration from the east“Large ancient-DNA study uncovers population that moved westwards 4,500 years ago.” — see also Massive Migration and Origins from greg cochran.

A story of 69 ancient Europeans – from dienekes. you need to read this one!

Genetic Characterization of Human Populations: From ABO to a Genetic Map of the British People – see map here @dienekes’.

Y chromosomes and Catalan surnames“‘By genotyping 17 Y-STRs and 68 SNPs in ~2500 male samples that each carried one of the 50 selected Catalan surnames, we could determine sets of descendants of a common ancestor, the population of origin of the common ancestor, and the date when such a common ancestor lived. Haplotype diversity was positively correlated with surname frequency, that is, rarer surnames showed the strongest signals of coancestry. Introgression rates of Y chromosomes into a surname by non-paternity, adoption, and transmission of the maternal surname were estimated at 1.5−2.6% per generation, with some local variation. Average ages for the founders of the surnames were estimated at ~500 years, suggesting a delay between the origin of surnames (twelfth and thirteenth centuries) and the systematization of their paternal transmission. We have found that, in general, a foreign etymology for a surname does not often result in a non-indigenous origin of surname founders; however, bearers of some surnames with an Arabic etymology show an excess of North African haplotypes.'” – @dienekes’.

Genetic evidence for an origin of the Armenians from Bronze Age mixing of multiple populations

Stone Age skeleton judged Norway’s oldest – 8000 years old.

Italic “Eteocretan” Sea peoples? – also @dienekes’.

Making Discoveries about Human Evolution Using 3D Technology

Make Love, Not Disease“New research on the genetic advantages of sexual reproduction has found that blending our genes through sex helps purge us of disease mutations.”

Human Genome Studies Reveal How Little Is Necessary To Explain the Human DNA Behind our Bigger Brains

Gene Changes Make Humans’ Sense of Taste Unique“Our ability to eat bitter plants help distinguish us from our ancestors and chimpanzees today.”

Dominance Genetic Variation Contributes Little to the Missing Heritability for Human Complex Traits – h/t gerome breen!

Elevated germline mutation rate in teenage fathers [pdf] – “We observe, as expected, that the overall mutation rate for fathers is seven times higher than for mothers. Also as expected, mothers have a low and lifelong constant DNA mutation rate. Surprisingly, however, we discover that (i) teenage fathers already set out from a much higher mutation rate than teenage mothers (potentially equivalent to 77–196 male germline cell divisions by puberty); and (ii) ageing men maintain sperm DNA quality similar to that of teenagers….” – h/t andrew sabisky! jayman tweeted: “8.2% false paternity rate in West Africans and 1.3% in Middle Easterners in this sample.”

Escape from crossover interference increases with maternal age – h/t billare! who tweeted: “Higher recombination rates in older women, being less concentrated in the usual hotspots. Men tend to stick w/theirs.”

Predicting and retrodicting intelligence between childhood and old age in the 6-Day Sample of the Scottish Mental Survey 1947“Terman–Merrill Stanford–Binet intelligence test scores at age 11 years correlated .72 with verbal intelligence at age 77. Adding another test from age 11 and educational took the multiple R to .81. National Adult Reading Test scores at age 77 and educational had a multiple R of .75 with IQ scores at age 11.” – h/t stuart ritchie! — see also Steady as she goes from dr. james thompson.

Peer effects: they exist but they’re not very big – from ben southwood.

Indian states: G and S factors – from emil kirkegaard.

State IQ estimates (2013) and 2013 IQ estimates by state, total and white only and State IQ estimates, blacks only (2013) and State IQ estimates, Hispanics only (2013) and IQ by race and parental educational attainment – from the awesome epigone.

Nailing liberalism / conservatism by the 50 U.S. States – from bryan pesta.

Low IQ ups risk of heavy drinking among men“The researchers analysed data collected from 49,321 Swedish males born during 1949 to 1951 and who were conscripted for Swedish military service from 1969 to 1971. IQ results were available from tests performed at conscription, and questionnaires also given at conscription provided data on total alcohol intake (consumed grams of alcohol/week) and pattern of drinking, as well as medical, childhood and adolescent conditions, and tobacco use. Adjustments were made for socio-economic position as a child, psychiatric symptoms and emotional stability and the father’s alcohol habits. ‘We found that lower results on IQ tests in Swedish adolescent men are associated with a higher consumption of alcohol, measured in both terms of total intake and binge drinking,’ Sjolund said.” h/t ruta akula!

Mathematical Proof Is Not Minutiae And Irreducible Complexity Is Not A Theory: A Final Response To Burt And Simons And A Call Tl Criminologists – from brian boutwell et al. brian tweeted: “Our second response to the call within Criminology to ban twin research.”

Familial Clustering of Tic Disorders and Obsessive-Compulsive Disorder – h/t amir sariaslan!

A two-dimensional model of psychopathy and antisocial behavior: A multi-sample investigation using items from the Psychopathy Checklist-Revised – h/t richard harper! who tweeted: “[P]sychopathy as fearless affect plus disinhibited lifestyle, then plus anti-social to get crime.”

Birds of a “bad” feather flock together: The Dark Triad and mate choice“[W]omen high in psychopathy considered the Dark Triad traits in potential male partners more physically attractive and desirable for an one-night stand, as well as a potential husband. Men who were high on psychopathy were likewise attracted to psychopathy in potential mothers.”

Cads and dads“Promiscuity and fidelity seem to be specific biological adaptations. Their manifestations in men and women are not as different as you might expect.” (whatever’s gotten into the economist these days?)

Genetic similarity between mates predicts extrapair paternity — a meta-analysis of bird studies

Who cares? Why evolution suggests parenting responsibility is seldom equally shared

Sex Differences in Preferences for Humor: A Replication, Modification, and Extension [pdf] – “[M]en prefer women who are receptive to their humor whereas women prefer men who produce humor. These findings held even after we modified Bressler et al.’s questionnaire for better conceptual validity. Furthermore, using a separate measure designed to assess trade-offs, we found that men viewed humor receptivity as a necessity and humor production as a luxury when they were asked to create an ideal long-term partner. For women, it was just the opposite.”

How Big are Psychological Sex Differences?“Sex Differences are Not Small if You Know Where to Look” – h/t claire lehmann!

Prenatal hyperandrogenic environment induced autistic-like behavior in rat offspring – h/t simon baron-cohen!

The influence of prenatal hormones on occupational choice: 2D:4D evidence from Moscow“Women in enterprising occupations exhibited lower measured 2D:4D ratios than average. Those in conventional and social work had higher 2D:4D ratios. Results confirm previous findings on 2D:4D and gender-specific occupational interests.”

Examining the Impact of Peer Group Selection on Self-Reported Delinquency: A Consideration of Active Gene–Environment Correlation – h/t jayman! who tweeted: “Do peers still influence adolescent delinquency after taking into account genetic influences? No.”

Socioeconomic status and sick leave granted for mental and somatic disorders: a prospective study of young adult twins“Low SES is associated with a higher level of sick leave granted for both mental and somatic disorders among young adults, but these associations are confounded by factors that are common to co-twins. Education and income are therefore not likely to strongly affect sick leave in young adulthood.”

List of genetic confounds – from emil kirkegaard.

Sibling differences in low birth weight, dopaminergic polymorphisms, and ADHD symptomatology“[L]ow birth weight siblings are at significantly greater risk of exhibiting symptoms of ADHD during childhood relative to their normal birth weight siblings. Moreover, possessing greater genetic risk on three dopaminergic genes (DAT1, DRD2, and DRD4) relative to a sibling appears to exacerbate the link between sibling differences in birth weight and sibling differences in ADHD symptomatology.”

What is different about the brains of “SuperAgers”“Compared with average elderly individuals, they found fewer Alzheimer-type neurofibrillary tangles and an increased packing density of von Economo neurons, especially in the anterior cingulate.”

“Bad genes” & criminal responsibility – MAOA stuff.

Heritability & the left“[T]here’s no conflict between leftism and a belief in the heritability of ability.” – that’s what i said! see also: Heritability, Left and Right.

What does it say about Owen Jones that he isn’t interested in scientific research?“What I find irritating about progressive politics is that it ignores and contradicts science, while at the same time pretending to be in favour of reason. The entire worldview is based on the tabula rasa idea of human nature which is contradicted by science. The blank slate makes the progressive goal of equality of outcomes possible; indeed, if equality is not achieved there can only be nefarious forces at work and ‘more work to be done’.” – from ed west. see also Fancy a job in academia or the media? Best brush up on the new political correctness“[Political correctness is] a faith, and it does not matter how daft the belief systems of a faith appear to a rational mind; if its critics sound backwards and out of touch and rural – literally ‘pagan’ – it will succeed.”

Both liberals and conservatives have anti-science biases, study finds“New research suggests that liberals, as well as conservatives, can be biased against science that doesn’t align with their political views.” — see also Nuclear Power and the Anti-Science Ideology of the “Progressive” Left from helian.

Why science is so hard to believe“Science appeals to our rational brain, but our beliefs are motivated largely by emotion, and the biggest motivation is remaining tight with our peers. ‘We’re all in high school. We’ve never left high school,’ says Marcia McNutt. ‘People still have a need to fit in, and that need to fit in is so strong that local values and local opinions are always trumping science. And they will continue to trump science, especially when there is no clear downside to ignoring science.'”

John Derbyshire On Culturalists vs. Biologians; Or, Where Is The American Harald Eia?

Have Mormons been bred for gullibility? – from agnostic.

Islam Is Not a Religion of the Book“By this, I mean that as a whole humans are prone to accepting the primary causal role of reflective cognition, of beliefs avowed and rationales offered. We are confident in our conscious self control, despite a robust body of cognitive psychology which implies that much of our cognition is not under the control or constraint of rational faculties. This problem is particularly extreme among intellectuals, the very class which also attempts to understand human phenomena. Through the simple process of introspection and extrapolation intellectuals tend to reduce human action to the outcome of ratiocination, inference from eternal axioms. This is wholly inadequate to a phenomenon as complex as religion.” – from razib.

Your DNA is everywhere. Can the police analyze it?“Supreme Court weighing if we must live in sealed bubbles to maintain DNA privacy.”

FDA panel could soon approve 23andMe home genetics test

Linguists link English, Hindi to single ancestor language spoken 6,500 years ago – h/t steve stewart williams!

Old India’s Village of Warriors Becomes Birthplace of Bouncers“Look closely and it becomes clear that the bouncers are all of a single physical type, their chests and biceps built like the front bumper of a sport utility vehicle. If they look like cousins, it is because they are. A startling number of them share a family name, Tanwar, and when the nightclubs close many will return to the same nearby village, a place where women walk down dusty lanes with their faces obscured by a cloth, balancing stacks of dried cow dung on their heads, much as their ancestors did three centuries ago…. The musclemen from the village of Fatehpur Beri are the descendants of the original inhabitants of the city, a genetic line that fortified itself over the course of centuries as they defended their village against waves of invaders on their way to the seat of empire. The sons and grandsons of cow and goat herders, they were born in an outpost surrounded on all sides by croplands. As Fatehpur Beri was swallowed by the expanding city, its spartan strongmen continued to train in the traditional way, stripping down to loincloths and wrestling in a circle of mud. But they were forced to look for a new line of work. ‘There is an element of the warrior in the Tanwars,’ said Ankur Tanwar, who opened the village’s first gym about a decade ago. ‘We fought with the Muslim invaders. We fought with the Britishers.'”

Ancient Egyptians had state-supported health care – at least some of them did.

bonus: Man’s best friend…unless you’re lying: How dogs can sense whether a person is trustworthy – h/t ninja economics! also: When you’re happy and you show it, dogs know it.

bonus bonus: The Cold May Have Cost Penguins Most of Their Taste Buds“Recent genetic analysis shows that penguins can’t taste sweet or bitter, and scientists think sub-zero temps may be to blame.”

bonus bonus bonus: Limpet teeth set new strength record

bonus bonus bonus bonus: Study Finds Jack Shit – h/t jayman!

bonus bonus bonus bonus bonus: Lost Sherlock Holmes story discovered

bonus bonus bonus bonus bonus bonus: a poem. (^_^)

bonus bonus bonus bonus bonus bonus bonus: #TheTitleOfMySexTape (~_^)

(note: comments do not require an email. limpet tooth.)

Ancient Jomon people not like present-day East Asians“‘We found a unique genetic position of the Jomon people who had diverged before the diversification of most of present-day East Eurasian populations including East Eurasian Islanders. This indicates that Jomon people were a basal population in East Eurasia and genetically isolated from other East Eurasians for long time.'” – h/t charles!

Uncovering the Genetic History of the Present-Day Greenlandic Population“[W]e analyzed ∼200,000 SNPs from more than 10% of the adult Greenlandic population (n = 4,674). We found that recent gene flow from Europe has had a substantial impact on the population: more than 80% of the Greenlanders have some European ancestry (on average ∼25% of their genome). However, we also found that the amount of recent European gene flow varies across Greenland and is far smaller in the more historically isolated areas in the north and east and in the small villages in the south. Furthermore, we found that there is substantial population structure in the Inuit genetic component of the Greenlanders and that individuals from the east, west, and north can be distinguished from each other. Moreover, the genetic differences in the Inuit ancestry are consistent with a single colonization wave of the island from north to west to south to east. Although it has been speculated that there has been historical admixture between the Norse Vikings who lived in Greenland for a limited period ∼600–1,000 years ago and the Inuit, we found no evidence supporting this hypothesis. Similarly, we found no evidence supporting a previously hypothesized admixture event between the Inuit in East Greenland and the Dorset people, who lived in Greenland before the Inuit.” – h/t razib!

Y chromosome super-fathers“Most of these lineages are so young that there are good chances that their founders were figures from history or mythology.” – from dienekes.

Bone Tool Discovered at Neanderthal Site in France“A bone tool from the Grotte du Bison at Arcy-sur-Cure in France is further evidence that Neanderthals had abilities usually attributed solely to modern humans….”

Early age of alcohol initiation is not the cause of alcohol use disorders in adulthood, but is a major indicator of genetic risk. A population-based twin study.“The association between early age of alcohol initiation and alcohol use disorders in later life does not reflect a causal relationship, but is due almost entirely to common genetic risk factors.”

α-Actinin-3: Why Gene Loss Is an Evolutionary Gain – h/t billare! who tweeted: “Positive selection for broken proteins: Derived ACTN3 mutation seems to help fast-twitch muscles fatigue less slowly.”

Do viruses make us smarter?“[R]etroviruses seem to play a central role in the basic functions of the brain, more specifically in the regulation of which genes are to be expressed, and when.”

Estimating the genotypic intelligence of populations and assessing the impact of socioeconomic factors and migrations – from davide piffer who tweeted: “New version of my paper with genetic distances. Migrations or drift less likely to explain results.” also, from the paper: “The results also provide preliminary evidence in favor of the hypothesis that poor environmental conditions (i.e. economic and sociocultural) tend to depress national IQ scores. Countries with lower per capita GDP and a lower index of Human Development tended to have larger positive ‘residuals’, that is the difference between the score predicted by the regression (of IQs for developed countries on the 4 SNPs g factor) and the actually measured IQ was larger in countries with lower GDP and HDI (r around 0.7). Thus, poorer and less developed countries have yet to reach their full intellectual potential. The results of this study indicate that the gaps in intellectual performance between some populations can be narrowed via adequate improvement of environmental conditions, however the overall pattern of intellectual scores is due to relatively stable and fixed (genetic) factors and cannot be substantially altered.” – see also terrific post from anatoly karlin on this paper!: Genetics, IQ, and Convergence.

Evidence of polygenic selection on human stature inferred from spatial distribution of allele frequencies – also from davide piffer.

Geographical Variation in Dementia: Examining the Role of Environmental Factors in Sweden and Scotland“We found a 2- to 3-fold geographical variation in dementia odds in Sweden, after twin random effects — likely to capture genetic and shared environmental variance — were removed. In Scotland, we found no variation in dementia odds in childhood but substantial variation, following a broadly similar pattern to Sweden, by adulthood. Conclusion: There is geographical variation in dementia rates.” – h/t erwin schmidt! – also Genetics and Underlying Pathology of Dementia.

Archaeogenomic insights into the adaptation of plants to the human environment: pushing plant–hominin co-evolution back to the Pliocene“The colonization of the human environment by plants, and the consequent evolution of domesticated forms is increasingly being viewed as a co-evolutionary plant–human process that occurred over a long time period, with evidence for the co-evolutionary relationship between plants and humans reaching ever deeper into the hominin past. This developing view is characterized by a change in emphasis on the drivers of evolution in the case of plants. Rather than individual species being passive recipients of artificial selection pressures and ultimately becoming domesticates, entire plant communities adapted to the human environment.” – h/t george perry!

Son of Edar“[S]omebody should look for characteristic racial differences in tears, sebaceous glands, Meobomian glands, and salivary glands. And possibly fingernails. They may well exist, be driven by this EDAR mutation, and some might play a role in its selective advantage.” – from greg cochran.

Quality vs Quantity“To the extent that human capital is a product of genetic factors (quite a lot), this tradeoff *does not exist*.” – also from greg cochran.

Lower mortality rates among Asian, Hispanic lupus patients“Asian and Hispanic patients with systemic lupus erythematosus (SLE) have lower mortality rates compared to Black, White, or Native Americans with the disease, scientists have found. Findings indicate that the risk for death among White patients is much lower than in Black and Native American SLE patients.”

Genetic errors linked to more ALS cases than scientists had thought – h/t jayman!

Is your face special?“Face recognition is highly heritable and weakly related to *g* so it probably has its own module, or a favoured set of circuits which only partly taps into the central processor power of general intelligence. So, not only is your face is special. but your specialised ability to recognise faces is even more special.” – from dr. james thompson.

Are flu shots effective? Your genetics determine how the immune system responds

Environment, more than genetics, shapes immune system“Everyone’s immune system is slightly different—a unique mixture of hundreds of these cells and proteins. But the main driver of this variation is unclear. Although scientists know that our immune system can adapt to our environment—that’s why vaccines work, for instance—it is also built by our genes…. After recruiting 210 identical and fraternal twins between 8 and 82 years old, Davis and colleagues took blood samples and measured more than 200 parameters of their immune systems. For example, they measured the numbers of 95 kinds of immune cells and 51 kinds of proteins. Today, the researchers report online in Cell that identical twins’ immune systems were too different for the variation to boil down to genetics. Indeed, environment overshadowed inheritance in three-quarters of the measurements, and half showed no measurable genetic influence. Moreover, younger twins were more similar than were older twins, evidence that as the twins aged and were exposed to different environments, their immune systems diverged over time.”

Levels of Selection Are Artefacts of Different Fitness Temporal Measures“I show by comparing the fitness of individuals with that of collectives of individuals in the same environment and over the same period of time – as required to decide if one or more levels of selection is acting in a population – that the selection of collectives is a by-product of selection at the individual level; thus, talking about two or more levels of selection represents merely a different perspective on one and the same process.”

Does incidental disgust amplify moral judgment? A meta-analytic review of experimental evidence [pdf] – “We meta-analyzed all available studies, published and unpublished, that experimentally manipulated incidental disgust prior to or concurrent with a moral judgment task (k=50). We found that there is evidence for a small amplification effect of disgust (d=.11), which is strongest for gustatory/olfactory modes of disgust induction. However, there is also some suggestion of publication bias in this literature, and when this is accounted for, the effect disappears entirely (d=-.01). Moreover, prevalent confounds mean that the effect size that we estimate is best interpreted as an upper bound on the size of the amplification effect. The results of this meta-analysis argue against strong claims about the causal role of affect in moral judgment and suggest a need for new, more rigorous research on this topic.” – h/t stuart ritchie!

The DNA photofit: Amazing breakthrough means police can tell suspect’s colour, height and even age – from a tiny speck of blood – daily mail.

The Coming Stability? The Decline of Warfare in Africa and Implications for International Security“The years 2010–2013 saw an increase of 35 per cent in African battle deaths over 2005–2010, but they still are 87 per cent lower than the 1990–1999 average…. Consequently, there is no Africa exception to the systemic shift towards lower levels of armed conflict.” – h/t mugwump!

The Scariest Explanation for America’s Vast Prison Population: We Want It That Way“[I]n federal prisons at least, Hispanics have overtaken blacks in the dubious distinction of being the most disproportionately imprisoned. Nor can we blame the war on drugs. The idea that vast numbers of Americans are in prison for smoking pot or snorting blow turns out to be a fantasy. About 20 percent of inmates are in for drug-related crimes, but those crimes are rarely limited to their own casual use. According to a 2004 estimate, only about 12,000 people were incarcerated for simple possession, without intent to traffic or distribute.”

Sorry, liberals, Scandinavian countries aren’t utopias“Finland, which tops the charts in many surveys (they’re the least corrupt people on Earth, its per-capita income is the highest in Western Europe and Helsinki often tops polls of the best cities), is also a leader in categories like alcoholism, murder (highest rate in Western Europe), suicide and antidepressant usage….” – [huh. even with all that tango dancing!] – “It turns out that the ‘warrior gene’ — actually the enzyme monoamine oxidase A, which is linked to impulsive behavior, violence and alcoholism — is especially prevalent in Finland. ‘Dark’ doesn’t just describe winter in the Arctic suburbs, it applies to the Finnish character.” – h/t ninja economics!

The relationship between anti-gay prejudice and the categorization of sexual orientation“[I]ndividuals reporting higher levels of anti-gay bias appear to be less accurate judges of sexual orientation.” but “Italians reporting greater anti-gay bias miscategorized fewer gay faces as straight.” – h/t ben southwood!

Legal Recognition of Same-Sex Couples and Family Formation“It has long been debated how legalizing same-sex marriage would affect (different-sex) family formation. In this article, I use data on OECD member countries for the period 1980–2009 to examine the effects of the legal recognition of same-sex couples (through marriage or an alternative institution) on different-sex marriage, divorce, and extramarital births. Estimates from difference-in-difference models indicate that the introduction of same-sex marriage or of alternative institutions has no negative effects on family formation…. In addition, the country-by-country case studies provide evidence of homogeneity of the estimated effects.”

Pair-Bonding, Romantic Love, and Evolution – The Curious Case of Homo sapiens“We conclude there is interdisciplinary support for the claim that romantic love and pair-bonding, along with alloparenting, played critical roles in the evolution of Homo sapiens.”

Sex ratio effects on reproductive strategies in humans – among the makushi people of guyana.

Antiquity of dairy farming in Ireland revealed“Research published today in the Journal of Environmental Archaeology shows that dairying on the island goes back approximately 6,000 years, revealed through traces of ancient dairy fats found in pots dating to around 4,000 to 2,500 BC.” – h/t frau katze!

The origin and evolution of maize in the American Southwest

A Breeder Apart: Farmers Say Goodbye to the Bull Who Sired 500,000 Offspring“Fans Commemorate ‘Toystory,’ a Dairy Legend With a Ravenous Libido” – the genghis khan of bulls! h/t mr. robert ford!

Items lost in the Stone Age are found in melting glaciers“Mittens, shoes, weapons, walking sticks – lost in the high mountains of Norway thousands of years ago – are now emerging from melting ice.”

bonus: ‘I can haz genomes’: cats claw their way into genetics“Canine dominance bows to tabby chic as cat sequencing takes off.”

bonus bonus: Some Microbes Can Eat And Breathe Electricity – whoa.

bonus bonus bonus: Britain’s oldest person Ethel Lang dies aged 114“Ethel Lang was believed to be the last person living in the UK who was born in the reign of Queen Victoria.” – h/t ed west!

bonus bonus bonus bonus: Two New Studies Posit At Least Two New Planets Out Beyond Pluto

bonus bonus bonus bonus bonus: Whaleworld: Looking for cetacean culture – h/t steve stewart williams! who tweeted: “Millions of years before human culture appeared, there was culture in the ocean.” – cool!

bonus bonus bonus bonus bonus bonus: Medieval Apps.

bonus bonus bonus bonus bonus bonus bonus: Archaeologists find 132-year-old Winchester rifle leaning against Nevada desert tree

bonus bonus bonus bonus bonus bonus bonus bonus: Irn Bru release 57 Scottish tartan labels and clan finder website promotion (~_^)

bonus bonus bonus bonus bonus bonus bonus bonus bonus: “At some German crossings you can play a game of Pong with the person standing at the other side.” (^_^)

bonus bonus bonus bonus bonus bonus bonus bonus bonus bonus: If birds in a truck fly, does the truck get lighter? – hey…don’t bogart that joint, new scientist!

bonus bonus bonus bonus bonus bonus bonus bonus bonus bonus bonus: Kareem Abdul-Jabbar to Publish a Novel About Sherlock Holmes’s Brother Mycroft – danced a few dances with kareem! (^_^) (not a euphemism. for anything!)

(note: comments do not require an email. i can haz genomz?)

African pygmies evolved their short stature twice“In the rainforests of Africa, being small is so helpful that it evolved twice in separate groups. Luis Barreiro of the University of Montreal in Quebec, Canada, and his colleagues identified 16 regions of the genome associated with short stature in the Batwa pygmies of Uganda. They then compared these regions in 169 Batwa and 74 Baka pygmies from West Africa. ‘In both groups, there was greater variation in those regions associated with being short, but no overlap between them,’ says Barreiro. This suggests they evolved their stature independently instead of inheriting the same ‘pygmy genes’ from a common ancestor.”

The strange history of the North American Arctic“Archaeologists mapping ancient cultures in the North American Arctic — a region spanning present-day Greenland — have long puzzled over how different cultures relate to one another. Now, an unprecedented large-scale genomics study has traced many such cultures to the Paleo-Eskimos, a people who early inhabited the harsh environment continuously for 4000 years, only to vanish mysteriously about 700 years ago. The discovery could change how scientists understand migration patterns in the North American Arctic…. After comparing the ancient and modern genetic data, the researchers found that the Saqqaq and Dorset cultures belonged to one Paleo-Eskimo people, whose genetic lineage continued in the region for more than 4000 years, from 3000 B.C.E. to 1300 C.E., contradicting previous theories that the diverse cultures came from different peoples. The Paleo-Eskimos are genetically distinct from Native Americans and Inuits, which means they represent a separate, later pulse of migration into the New World, says evolutionary geneticist Eske Willerslev of the University of Copenhagen, a co-author of the study. This contradicts previous theories that humans arrived in the Americas in three waves, painting a scenario of four waves instead — the Amerinds, the Na Dene Native Americans, the Paleo-Eskimos, and the Neo-Eskimo Thules…. What intrigues researchers most is why the Paleo-Eskimo lineage disappeared after the late Dorsets, around the same time that Neo-Eskimo Thules expanded rapidly to the Arctic. Archaeologists have found no evidence of violent conflict between the Thules and the Dorsets, but it would be hard to ignore contrasts between the two groups. The whale-hunting Thules lived in large, well-organized villages and boasted advanced technologies such as dog sleds and sinew-backed bows. The Dorsets, on the other hand, lived in small villages of 20 to 30 people and hunted with chipped stone blades. The researchers suspect that the Dorsets might have been pushed out to the fringes of the Arctic, or perhaps annihilated by a disease. ‘It’s just mind-blowing to imagine an entire people who just completely vanished,’ Willerslev says.” — see also Degüello from greg cochran.

Genetic changes transformed wild rabbits into tame bunnies, DNA study reveals“When humans domesticated wild rabbits and turned them into pet store favorites, they also changed their genome, a study has found…. The domestication of rabbits happened much more recently than that of cattle, sheep, pigs and dogs, which happened between about 15,000 and 9,000 years ago. Monks in monasteries in the south of France first domesticated northwestern europeans rabbits around 1,400 years ago…. [T]he researches report in the journal Science, small pre-existing genetic variations — sometimes just one letter of DNA code — started to become more common in the animals as they became domesticated. These variations generally didn’t affect the genes themselves, but rather acted on the genome’s regulatory regions, which are in control of whether genes are turned on or off. ‘Wild and domestic rabbits do not differ so much in actual protein sequences, but in how gene and protein expression is regulated,’ says Andersson. Among the genes particularly targeted during domestication were those involved in rabbits’ brains and nervous systems. That’s to be expected, Andersson says, because the differences between domestic and wild rabbits are almost all behavioral, while physical differences are slight…. Domestication of rabbits was made easier because the wild variety is a highly polymorphic species that already possesses many of gene variants selectively enhanced during domestication, the researchers say. That is likely to have been the case with most domesticated species, they say. ‘We predict that a similar process has occurred in other domestic animals and that we will not find a few specific genes that were critical for domestication,’ Andersson says.” — see also: Rabbit genome analysis reveals a polygenic basis for phenotypic change during domestication.

Comparative population genomics in animals uncovers the determinants of genetic diversity – h/t lars penke! who tweeted: “Across species, higher genetic diversity is not predicted by ecology, but by faster life history.”

Genome-wide genotype and sequence-based reconstruction of the 140,000 year history of modern human ancestry“We investigated ancestry of 3,528 modern humans from 163 samples. We identified 19 ancestral components, with 94.4% of individuals showing mixed ancestry. After using whole genome sequences to correct for ascertainment biases in genome-wide genotype data, we dated the oldest divergence event to 140,000 years ago. We detected an Out-of-Africa migration 100,000–87,000 years ago, leading to peoples of the Americas, east and north Asia, and Oceania, followed by another migration 61,000–44,000 years ago, leading to peoples of the Caucasus, Europe, the Middle East, and south Asia. We dated eight divergence events to 33,000–20,000 years ago, coincident with the Last Glacial Maximum. We refined understanding of the ancestry of several ethno-linguistic groups, including African Americans, Ethiopians, the Kalash, Latin Americans, Mozabites, Pygmies, and Uygurs, as well as the CEU sample. Ubiquity of mixed ancestry emphasizes the importance of accounting for ancestry in history, forensics, and health.” — don’t miss figure 2!

Seals May Have Carried Tuberculosis To The New World — thousand-year-old skeletons from peru suggest seals brought tuberculosis to americas.

Y Chromosomes of 40% Chinese Descend from Three Neolithic Super-Grandfathers“This observation suggests that the main patrilineal expansion in China occurred in the Neolithic Era and might be related to the development of agriculture.”

Blue Eyes Are More Common Than Any Other Colour in Britain“The Blue Eyes Project has found that although all eyes in Britain were once brown, they are now 48% blue, 30% green and just 22% brown…. The study mapped eye colour across the UK and Ireland and found that Scottish and Irish people are more likely to have blue eyes than in other parts of the UK, particularly the south. Just over a third (35%) of the population of south-west England and 41% in east England have blue eyes, compared to 57% in southeast Scotland…. Blue eyes are the result of a variant in the HERC2 gene, which, when it mutates, switches off the supply of brown-eye forming melanin, researchers say. Green eyes are also a result of this change, because they arise from a combination of the blue variant with brown. The first gene mutation resulting in blue eyes is understood to have occurred in the Baltic region around 10,000 years ago.”

Neanderthals in Europe Died Out Thousands of Years Sooner Than Some Thought, Study Says

The Other Neanderthal – h/t billare! who tweeted: “‘Denisovans are an example of…how mitochondrial DNA [misleads], & only the nuclear genome tells the full story.'”

Admixture in South African Afrikaners — from razib.

Finland’s love of milk dates back to the Stone Age“A combined team from the Universities of Bristol (England) and Helsinki (Finland) have been examining examples of Corded Ware pottery found in the northern parts of Finland. The pieces examined were cooking pots dated at 3,900 to 3,300 BCE and also approx. 2,500 BCE. Astonishingly the pots from 2,500 BCE contained traces of milk fats. This proved that the inhabitants at that time, despite a climate where it can snow for up to four months of the year, had domesticated animals.”

Holding a Mirror to Their Natures“[U]nrelated look-alikes showed little similarity in either personality or self-esteem. By contrast, twins — especially identical twins — score similarly on both scales, suggesting that the likeness is largely because of genetics…. Personality traits do not appear to be influenced by the way people are treated because of appearance. Moreover, they found, there appears to be no special bond between look-alikes. Helen Fisher, a biological anthropologist at Rutgers University who is also an identical twin, praised that study, saying it went to the heart of what makes people form a bond. ‘Even in cases where a person is a dead ringer for another, the natural pull is not there,’ Dr. Fisher said, ‘which builds the case that there is an underlying biology to kinship.'” — h/t steve stewart williams!

On the genetic architecture of intelligence and other quantitative traits — from steve hsu. h/t richard harper! who tweeted: “cognitive ability gene search requires sample sizes of 10,000 genes across a million persons.”

Genes Influence Young Children’s Human Figure Drawings and Their Association With Intelligence a Decade Later“Do genes influence individual differences in this species-typical behavior, and is drawing related to intelligence (g) in modern children? We report on the first genetically informative study of children’s figure drawing. In a study of 7,752 pairs of twins, we found that genetic differences exert a greater influence on children’s figure drawing at age 4 than do between-family environmental differences. Figure drawing was as heritable as g at age 4 (heritability of .29 for both). Drawing scores at age 4 correlated significantly with g at age 4 (r = .33, p < .001, n = 14,050) and with g at age 14 (r = .20, p < .001, n = 4,622). The genetic correlation between drawing at age 4 and g at age 14 was .52, 95% confidence interval = [.31, .75]. Individual differences in this widespread behavior have an important genetic component and a significant genetic link with g." – h/t rosalind arden!

Differences in intelligence between ethnic minorities and Han in China

The Canadian IQ calculated from the standardization of the WAIS IV eh? — h/t emil kirkegaard (no relation)!

Genome-wide screening for DNA variants associated with reading and language traits

Differences in cognitive abilities among primates are concentrated on G: Phenotypic and phylogenetic comparisons with two meta-analytical databases“Using meta-analytic databases of ethological observations of cognitive abilities involving 69 primate species, we found that cognitive abilities that load more strongly on a common factor (which is here termed G, in line with the terminology developed in previous literature to describe aggregated measures of general intelligence) are associated with significantly bigger interspecies differences and bigger interspecies variance. Additionally, two novel evolutionary predictions were made: more G-loaded abilities would present (1) weaker phylogenetic signals, indicating less phylogenetic conservativeness, and (2) faster rates of trait evolution, as it was hypothesized that G has been subjected to stronger selection pressures than narrower, more domain-specific abilities. These predictions were corroborated with phylogenetic comparative methods, with stronger effects among catarrhines (apes and Old World monkeys) than within the entire primate order. These data strongly suggest that G is the principal locus of selection in the macroevolution of primate intelligence. Implications for the understanding of population differences in cognitive abilities among human populations and for the theory of massive modularity applied to intelligence are discussed.” – h/t erwin schmidt!

The Flynn Effect: A Meta-Analysis [pdf] – h/t jelte wicherts! who tweeted: “IQ [continues] to go up with 3 points per decade. New meta-analysis shows no evidence of diminishing Flynn Effect.”

The Elusive X-Factor, or Why Jonathan Kaplan Is Wrong about Race and IQ – @humanvarieties.

Coevolution of languages and genes“[E]volutionary processes are more complex than simple models of gene-language coevolution predict, with linguistic boundaries only occasionally functioning as barriers to gene flow. More frequently, admixture takes place irrespective of linguistic differences, but with a detectable impact of contact-induced changes in the languages concerned.” – h/t jayman!

Does Natural Law exist?“While certain notions of right and wrong can apply to all humans, much of what we call ‘morality’ will always be population-dependent. What is moral in one population may not be in another.” – from peter frost.

Morality: The Amazing Side-Taking Machine“If there are so many evolutionary pathways to nice behaviors, and if many animals are cooperative, including bees, bats, hyenas, and monkeys, then perhaps the elaborate paraphernalia of human morality — explicit rules of behavior, moral taboos, moral debates, accusations, impartiality, punishments — are not needed to make people nice. Right? This is exactly what psychological research indicates. Developmental evidence shows that children are nice to people before acquiring adult-like moral judgment. Moreover, when children develop moral judgment, it does not prevent them from taking actions they judge wrong such as lying or stealing. In adults, research shows that moral judgments differ from and can even oppose altruistic motives. Research on hypocrisy shows that people are mostly motivated to appear moral rather than to actually abide by their moral judgments. Research on ‘motivated reasoning’ shows that people deviously craft moral justifications to push their own agendas. In short, people can be nice without morality and nasty with morality — altruism and morality are independent. In fact, humans are more eager to judge other people than to follow their own moral advice. Moral condemnation of other people’s behavior is distinctly, perhaps uniquely, human. So, what is the evolutionary function of condemnation…? People can use moral judgment to assess the wrongness of fighters’ actions and then choose sides against whoever was most immoral. When all bystanders use this strategy, they all take the same side and avoid the costs of escalated fighting. That is, moral condemnation functions to synchronize people’s side-taking decisions. This moral strategy is, of course, mostly unconscious just like other evolved programs for vision, movement, language, and so on.”

The roots of human altruism“[T]he willingness to provision others varies greatly from one primate species to the next. But there was a clear pattern, as summarized by Burkart: ‘Humans and callitrichid monkeys acted highly altruistically and almost always produced the treats for the other group members. Chimpanzees, one of our closest relatives, however, only did so sporadically.’ Similarly, most other primate species, including capuchins and macaques, only rarely pulled the lever to give another group member food, if at all – even though they have considerable cognitive skills. Until now, many researchers assumed that spontaneous altruistic behavior in primates could be attributed to factors they would share with humans: advanced cognitive skills, large brains, high social tolerance, collective foraging or the presence of pair bonds or other strong social bonds. As Burkart’s new data now reveal, however, none of these factors reliably predicts whether a primate species will be spontaneously altruistic or not. Instead, another factor that sets us humans apart from the great apes appears to be responsible. Says Burkart: ‘Spontaneous, altruistic behavior is exclusively found among species where the young are not only cared for by the mother, but also other group members such as siblings, fathers, grandmothers, aunts and uncles.’ This behavior is referred to technically as the ‘cooperative breeding’ or ‘allomaternal care.'”

Feminist activist women are masculinized in terms of digit-ratio and dominance: A possible explanation for the feminist paradox“The feminist movement purports to improve conditions for women, and yet only a minority of women in modern societies self-identify as feminists. This is known as the feminist paradox…. We measured the 2D:4D digit ratios (collected from both hands) and a personality trait known as dominance (measured with the Directiveness scale) in a sample of women attending a feminist conference. The sample exhibited significantly more masculine 2D:4D and higher dominance ratings than comparison samples representative of women in general, and these variables were furthermore positively correlated for both hands. The feminist paradox might thus to some extent be explained by biological differences between women in general and the activist women who formulate the feminist agenda.”

Global genetic variations predict brain response to faces“[A] significant proportion of the brain response to facial expressions is predicted by common genetic variance in a subset of regions constituting the face network. These regions show the highest inter-individual variability in the number of connections with other network nodes, suggesting that the genetic model captures variations across the adolescent brains in co-opting these regions into the face network.” – h/t razib!

Brain, behavior and genetics“Regardless of where the science now lies, we know that biology controls behavior. Our actions and thoughts aren’t magic, they rely on the biochemistry of neurotransmitters and nerve signals. They have physical substrates that are controlled by our genes….”

The impact of neighbourhood deprivation on adolescent violent criminality and substance misuse: A longitudinal, quasi-experimental study of the total Swedish population“We found that the adverse effect of neighbourhood deprivation on adolescent violent criminality and substance misuse in Sweden was not consistent with a causal inference.” — see also Depraved on account of being deprived? from dr. james thompson.

Does Urban Living Cause Mental Illness? – h/t jayman! who tweeted: “Interview w/ @AmirSariaslan, on his work showing that adverse environments don’t cause schizophrenia, & killing GxE.”

Daughters provide as much elderly parent care as they can, sons do as little as possible — h/t frau katze!

Honor: The Cause of — and Solution to — All of Society’s Problems“Centuries-old cultural norms don’t change overnight….” — gee, i wonder why? (where does culture come from?)

Social sciences suffer from severe publication bias“Survey finds that ‘null results’ rarely see the light of the day.” – h/t claire lehmann!

Haidt: “Political Diversity Will Improve Social Psychological Science” – from steve sailer.

How Do Liberal and Conservative Attitudes About Obedience to Authority Differ? The Surprising Result of My Study“Together with my collaborators Dr. Danielle Gaucher and Nicola Schaefer, we asked both red and blue Americans to share their views about obeying liberal authorities (e.g., ‘obey an environmentalist’). In an article that we recent published in Personality and Social Psychology Bulletin, we found that liberals were now the ones calling for obedience. And when the authorities were viewed as ideologically neutral (e.g., office manager), liberals and conservatives agreed. Only when people perceived the authority to be conservative (e.g., religious authority) did conservatives show a positive bias.”

The Kennewick Man Finally Freed to Share His Secrets

Measuring Inbreeding in the Greek Gods“it seems that Ares has an inbreeding coefficient of 37.5%. This is due to the fact that his parents—Zeus and Hera—are siblings, as well as his grandparents with each other. Zeus has an inbreeding coefficient of 25%.” — (^_^)

bonus: Walking fish raised on land mimic ancient evolutionary transition

bonus bonus: Why are all our wagtails vanishing? Scientists baffled by long-term decline of three species in Britain“The three wagtail species spotted on our shores are the Yellow Wagtail, a farmland bird that migrates to sub-Saharan Africa, and two which largely remain in the UK over the winter, the Grey Wagtail, a river specialist, and the familiar Pied Wagtail. Researchers said the races of both Pied and Yellow Wagtail breeding in the UK nest almost nowhere else in the world…. Sarah Harris, BBS Organiser at the British Trust for Ornithology, said: ‘I find it fascinating that three seemingly similar birds, the Yellow, Grey and Pied Wagtail can lead such different lives and face such a variety of challenges. With the UK races of two of these species – Pied and Yellow Wagtails – being largely confined to our islands, these population changes are of global conservation significance….'” – ornithologists are soooo waaaaycist! they make me sick! (~_^)

(note: comments do not require an email. biophobia. (~_^) )

I can’t afford to think about that“[W]hy are balls of steel so rare in academia? Do they undergo a procedure?” – from greg cochran.

Species Do Not Exist“[T]he Endangered Species Act has shaky conceptual foundations…. And yet we somehow deal with the fact that the universe is complex when it comes to species, although not with races.” – from steve sailer. see also Should You Fear the Pizzly Bear? h/t werner jensen!

Catastrophes in evolution: Is Cuvier’s world extinct or extant?

Million year hominid dispersal event in Iberia“Archaeological remains dating to between 1 million to 780,000 years were also found on an excavation that has provided evidence of the first known human occupation in the Iberian Peninsula.” – h/t cultevobot!

Early Exit: When Did Modern Humans First Leave Africa?“[A] recent study in Proceedings of the National Academy of Sciences of the genes of indigenous people in southeast Asia has suggested a much earlier date for the first human explorers. Professor Katerina Harvati-Papatheodorou and lead author Hugo Reyes-Centeno of the University of Tubingen in Germany and their colleagues fed this genetic data into a computer model of migration and found that the best explanation was an African exodus around 130,000 years ago, more than twice as far back as most scientists think. They also suggested that this early wave took a different route, spreading along the south coasts of Arabia and Asia towards Australia.”

Early modern humans were ‘culturally diverse’ before they left Africa“Researchers have carried out the biggest ever comparative study of stone tools dating to between 130,000 and 75,000 years ago found in the region between sub-Saharan Africa and Eurasia. They have discovered there are marked differences in the way stone tools were made, reflecting a diversity of cultural traditions. The study has also identified at least four distinct populations, each relatively isolated from each other with their own different cultural characteristics.”

Indo-Europeans preceded Finno-Ugrians in Finland and Estonia“An archaic (Northwest-)Indo-European language and a subsequently extinct Paleo-European language were likely spoken in what is now called Finland and Estonia, when the linguistic ancestors of the Finns and the Sami arrived in the eastern and northern Baltic Sea region from the Volga-Kama region probably at the beginning of the Bronze Age.” – @dienekes’.

168 South Asian Genomes – @dienekes’.

Claim: Modern human teeth in southern China 70-125 ka BP – h/t razib!

The Most Violent Era In America Was Before Europeans Arrived“[A] new paper finds that the 20th century, with its hundreds of millions dead in wars and, in the case of Germany, China, Russia and other dictatorships, genocide, was not the most violent – on a per-capita basis that honor may belong to the central Mesa Verde of southwest Colorado and the Pueblo Indians. Writing in the journal American Antiquity, Washington State University archaeologist Tim Kohler and colleagues document how nearly 90 percent of human remains from that period had trauma from blows to either their heads or parts of their arms. ‘If we’re identifying that much trauma, many were dying a violent death,’ said Kohler. The study also offers new clues to the mysterious depopulation of the northern Southwest, from a population of about 40,000 people in the mid-1200s to 0 in 30 years.” – h/t hbd bibliography!

The ‘six universal’ facial expressions are not universal, cross-cultural study shows“It’s a con­cept that had become uni­ver­sally under­stood: humans expe­ri­ence six basic emotions — happiness, sad­ness, anger, fear, dis­gust, and surprise — and use the same set of facial move­ments to express them…. The only problem with this con­cept, according to North­eastern Uni­ver­sity Dis­tin­guished Pro­fessor of Psy­chology Lisa Feldman Bar­rett, is that it isn’t true at all…. [W]hat were assumed to be ‘psy­cho­log­ical uni­ver­sals’ may in fact be ‘Western’ — or per­haps even ‘American’ — cultural cat­e­gories.”

The intelligent pursuit of happiness“Intelligence is associated with health and longevity, and more intelligent children on average tend to live longer and healthier lives than less intelligent children, although it is not known why. Health is significantly associated with psychological well-being. So, it is possible that more intelligent individuals are more stable in their happiness over time because they are more likely to remain constantly healthy than less intelligent individuals.” – from dr. james thompson.

Clues emerge to genetic architecture of intelligence in children“‘When we computed the contribution of common variants to these cognitive abilities, we found that some of the contributions were substantial,’ said Hakonarson. For instance, common SNPs accounted for roughly 40 percent of the population differences in nonverbal reasoning, and 30 percent of the differences in language reasoning, with the balance of the differences attributable to rare variants and environmental factors. On the other hand, common gene variants together contributed to only 3 percent of the differences in spatial memory—the ability to navigate in a geographical location. There also were significant overlaps between trait domains. Reading ability, which was 43 percent attributable to common variants, was often inherited together with language reasoning abilities.” – h/t nolasco!

Lead released from African cookware contaminates food“Researchers tested 29 samples of aluminum cookware made in Cameroon and found almost all had considerable lead content. This cookware is common throughout Africa and Asia and is made from recycled scrap metal including auto and computer parts, cans, and other industrial debris. Lead exposure in children is linked to brain damage, mental retardation, lower educational performance, and a range of other health effects.” – h/t science enabled!

Facial fluctuating asymmetry is not associated with childhood ill-health in a large British cohort study – h/t jelte wicherts! who tweeted: “Contrary to several small N studies, large study finds no relationship between health measures & facial asymmetry.”

Structural Growth Trajectories and Rates of Change in the First 3 Months of Infant Brain Development – h/t simon baron-cohen! who tweeted: “Typical brain growth from birth to 3 months old: the brain grows 1% per day, and male brains grow faster.”

Workaholism: The addiction of this century“Workaholics scored higher on three personality traits: Agreeableness, Neuroticism, Intellect/Imagination.” – h/t claire lehmann!

Twins separated at birth reveal staggering influence of genetics“Segal, who wrote a book about the study called ‘Born Together Reared Apart: The Landmark Minnesota Twins Study’ (Harvard University Press, 2012), is now doing a prospective study of Chinese twins raised apart, often in different countries, by adoptive families.”

The association between grandparenthood and mortality – h/t neuroskeptic! who tweeted: “People who become grandparents at an early age tend to die sooner.” – because they have faster life histories?

Getting the babes but not the babies“Who’s making more babies? ‘Good boys’ or ‘bad boys’? Originally, the good boys were, thanks to parental monitoring of relations between single men and single women. The pendulum then swung toward the bad boys in the 1940s, only to swing back after the 1960s.” – from peter frost.

Population-level variability in the social climates of four chimpanzee societies – h/t erwin schmidt! who tweeted: “Some groups of chimpanzees are more egalitarian than others.”

Is empathy in humans and apes actually different? ‘Yawn contagion’ effect studied“Humans and bonobos are the only two species in which it has been demonstrated that yawn contagion follows an empathic trend, being more frequent between individuals who share a strong emotional bond, such as friends, kin, and mates…. Two features of yawn contagion were compared: how many times the individuals responded to others’ yawns and how quickly. Intriguingly, when the yawner and the responder were not friends or kin, bonobos responded to others’ yawns just as frequently and promptly as humans did. This means that the assumption that emotional contagion is more prominent in humans than in other species is not necessarily the case. However, humans did respond more frequently and more promptly than bonobos when friends and kin were involved, probably because strong relationships between humans are built upon complex and sophisticated emotional foundations linked to cognition, memory, and memories. In this case, the positive feedback linking emotional affinity and the mirroring process seems to spin faster in humans than in bonobos. In humans, such over-activation may explain the potentiated yawning response and also other kinds of unconscious mimicry response, such as happy, pained, or angry facial expressions.”

Self-regulatory failure and the perpetration of adolescent dating violence: Examining an alcohol use by gene explanation“[A]lcohol use was more strongly associated with dating violence among adolescents who had a high rather than a low multilocus genetic profile composed of five genetic markers that influence dopamine signaling. Alcohol use was more strongly related to dating violence among boys with long rather than short 5-HTTLPR alleles, the opposite of the prediction. MAOA-uVNTR did not interact with alcohol, but it had a main effect on dating violence by boys in later grades in the expected direction: boys with more low activity alleles perpetrated more dating violence. Exploratory analyses found variation in findings by race.” – h/t unsilenced science!

Take Two Sugar Pills and Call Me in the Morning“Over the past decade, a number of clinical studies have begun to show that people who improve on placebos are genetically different than those who don’t.” – h/t billare! see also here.

Designer babies: selection vs editing – @steve hsu’s.

Anxiety in invertebrates opens research avenues“[N]euronal mechanisms related to anxiety have been preserved throughout evolution. This analysis of ancestral behavior in a simple animal model opens up new avenues for studying the neuronal bases for this emotion.”

Our Microbiome May Be Looking Out for Itself – sneaky microbiome! h/t mr. robert ford!

New Study To Look At The Genetics Of Inflammatory Bowel Disease – from 23andMe.

Constitutional verbosity and social trust – h/t heartiste! who tweeted: “The more a nation’s people trust each other, the fewer words they need to codify that trust.”

War in the womb“A ferocious biological struggle between mother and baby belies any sentimental ideas we might have about pregnancy” -h/t charles!

Head Count – ‘Malthus,’ by Robert J. Mayhew

New Saudi ban on marriage to foreigners stirs controversy“[A] new law bans Saudi men from marrying women from Pakistan, Bangladesh, Chad and Burma.” (not a big surprise from the najdis.)

Avoid marrying kin, behave ‘softly on first night’“A notice from the Health Ministry [of turkey-h.chick] on ‘Consultancy before Marriage’ has highlighted that one out of every five marriages are among kin. The recently released document also includes sexual advice for couples, especially for the ‘first night.’ ‘Consanguineous marriage is mostly among first-degree relatives, increasing the number of rare genetic diseases,’ it said. ‘This matter is noteworthy. Those who are married to kin and those who carry genetic diseases should consult a health institution before gestation.'” – h/t anatoly karlin!

Avoiding Prince Joffrey: Primates have newly discovered ability that stops inbreeding“[N]ew research in macaques has revealed for the first time that primates are able to recognise their own relatives. The researchers opted for macaques rather than chimps for their study as the former lives in larger groups with more relatives; allowing them to pick distantly related monkeys who haven’t met, they could rule out ‘familiarity’ as a way for figuring out who is related…. The researchers had no clue as to how they were able to do this. Perhaps they did make a ‘template’ based on relatives they were familiar with, or maybe they had figured out what they looked like somehow, so could use that to figure out who were their relatives.”

Download Pew Datasets!

bonus: Researchers create 1,000-robot swarm – PANIC!!1! HEAD FOR THE HILLS!!

bonus bonus: The Domestic Cat Genome Has Been Fully Sequenced, and It’s Fascinating“Cats also have what biologists call “a highly conserved ancestral mammal genome organization,” which means that many stretches of their genome haven’t changed much over evolutionary time. Put simply, domestic cats haven’t changed much since they first evolved.”

bonus bonus bonus: Reconstructions show how some of the earliest animals lived — and died – rangeomorphs. h/t mike anissimov!

bonus bonus bonus bonus: Shortest-known abstract for a serious scientific paper (^_^)

(note: comments do not require an email. happy capybara!)

Quick Questions for Peter and Rosemary Grant“There is widespread misunderstanding about evolution; that it occurs extremely slowly and therefore cannot be studied in a person’s lifetime. This was the view of Charles Darwin. Many biologists and others now know that this is not correct…. The idea that animals as large as birds might evolve before our eyes is not so well known, yet our study in the entirely natural world of Daphne Major island has revealed this does in fact happen when there is a change in the environment, and it takes place over a period as short as a year, and repeatedly.” – h/t billare!

Is DNA Multilingual?“The genetic code has traditionally been viewed as a universal set of instructions, exquisitely tuned to maintain robust stability and allow evolution-sustaining mutations. But the pervasive occurrence of recoded stop codons, and the backchannel crosstalk between microbes and viruses, paints a more intricate picture of multilingual genetic instructions.”

Jelly genome mystery“The uniqueness of this ctenophore’s nervous system leads Moroz and his team to argue that it must have evolved independently, after the ctenophore lineage branched off from other animals some 500 million years ago.”

Genomic divergence in a ring species complex“Ring species provide particularly clear demonstrations of how one species can gradually evolve into two, but are rare in nature…. Here we use genome-wide analyses to show that, although spatial patterns of genetic variation are currently mostly as expected of a ring species, historical breaks in gene flow have existed at more than one location around the ring, and the two Siberian forms have occasionally interbred.” – h/t razib!

Natural selection and infectious disease in human populations“The ancient biological ‘arms race’ between microbial pathogens and humans has shaped genetic variation in modern populations, and this has important implications for the growing field of medical genomics. As humans migrated throughout the world, populations encountered distinct pathogens, and natural selection increased the prevalence of alleles that are advantageous in the new ecosystems in both host and pathogens. This ancient history now influences human infectious disease susceptibility and microbiome homeostasis, and contributes to common diseases that show geographical disparities, such as autoimmune and metabolic disorders.”

High genetic differentiation between populations often driven by classic selective sweeps“‘We demonstrate that while sites of low differentiation represent sampling effects rather than balancing selection, sites showing extremely high population differentiation are enriched for positive selection events and that one half may be the result of classic selective sweeps. Among these, we rediscover known examples, where we actually identify the established functional SNP, and discover novel examples including the genes ABCA12, CALD1 and ZNF804, which we speculate may be linked to adaptations in skin, calcium metabolism and defense, respectively. Conclusions: We have identified known and many novel candidate regions for geographically restricted positive selection, and suggest several directions for further research.'” – @dienekes’.

Mendelian-Mutationism: The Forgotten Evolutionary Synthesis – h/t neuroskeptic! who tweeted: “Did geneticists ‘crack’ the secret of evolution much earlier than believed?”

this one’s for linton!: Why Marrying Your Cousin May Pay Off“In line with previous findings, the researchers found that among non-foraging societies, a couple’s relatedness was linked with having more surviving children. But among foraging societies, the opposite was true: More-closely related spouses had fewer surviving children. Furthermore, the more family intermarriage in a society, the greater the benefit of intermarrying on the number of children couples had. In other words, in societies in which people frequently married their relatives, intermarrying showed a stronger link to having more children.”

The Closest of Strangers“[I]dentical twins who are aunts and uncles invest more in caring for the children of their twins (their ‘genetic’ sons and daughters) than do fraternal twins.”

Why Do Honor Killings Defy the First Law of Homicide? And Will Smaller Families Lead to Fewer Of Them? – h/t tom farsides! – previously: inclusive inclusive fitness.

Genetic and educational assortative mating among US adults“We find that spouses are more genetically similar than two individuals chosen at random but this similarity is at most one-third the magnitude of educational similarity.”

Irish fair skin can be traced to India and the Middle East“A major new US study at Penn State University has found that Europeans’ light skin stems from a gene mutation from a single person who lived 10,000 years ago…. Keith Cheng from Penn State College of Medicine reported that one amino acid difference in the gene SLC24A5 is a key contributor to the skin color difference between Europeans and West Africans…. ‘The mutation in SLC24A5 changes just one building block in the protein, and contributes about a third of the visually striking differences in skin tone between peoples of African and European ancestry, he said…. The mutation, called A111T, is found in virtually everyone of European ancestry. A111T is also found in populations in the Middle East and Indian subcontinent, but not in high numbers in Africans. All individuals from the Middle East, North Africa, East Africa and South India who carry the A111T mutation share traces of the ancestral genetic code. According to the researchers, this indicates that all existing instances of this mutation originate from the same person.” – h/t 23andMe!

The puzzle of European hair, eye, and skin color“The physical appearance of Europeans seems to result from a selection pressure that acted primarily on women and only secondarily on men. This is especially true for highly visible traits on or near the face—the focus of visual attention.” – from peter frost.

The Dark Triad of Personality – special issue of Personality and Individual Differences. – h/t claire lehmann!

Heritability of brain volume change and its relation to intelligence“Human brain volumes change throughout life, are highly heritable, and have been associated with general cognitive functioning…. Results show that changes in volumes of total brain (mean=-6.4ml; -0.5% loss), cerebellum (1.4ml, 1.0% increase), cerebral white matter (4.4ml, 0.9% increase), lateral ventricles (0.6ml; 4.8% increase) and in surface area (-19.7cm2, -1.1% contraction) are heritable (h2=43%; 52%; 29%; 31%; and 33%, respectively). An association between IQ (available for 91 participants) and brain volume change was observed, which was attributed to genes involved in both the variation in change in brain volume and in intelligence. Thus, dynamic changes in brain structure are heritable and may have cognitive significance in adulthood.”

Cognitive abilities amongst the Sámi population“Lapps have an IQ around 100.8 are tilted towards visuospatial ability and away from verbal ability.” – from elijah armstrong, michael woodley the younger, and richard lynn. edit: original paper here on elijah’s blog! (^_^)

The Flynn Effect in a Nutshell – from elijah.

Does brain structure determine your political views?“‘People like to believe that their own political beliefs are rational, that they’re a sensible response to the world around them, so when we come along and say, “Maybe there are these predispositions, influential but perhaps not fully in your conscious awareness,” that’s not the way we like to view our own political beliefs.'” – h/t mr. robert ford!

Sex-Related Neuroanatomical Basis of Emotion Regulation Ability“Behavioral research has demonstrated that males have a higher capability of regulating their own and others’ emotions than females; however, little is known about the sex-specific brain mechanisms involved in emotion regulation ability…. we found the sex differences in the neuroanatomical basis of emotion regulation ability. Males showed a stronger positive relation between emotion regulation ability and regional gray matter volume (rGMV) in the right dorsolateral prefrontal cortex. In contrast, females demonstrated a stronger positive relation between emotion regulation ability and rGMV in an anatomical cluster that extends from the left brainstem to the left hippocampus, the left amygdala and the insular cortex.”

More Maps of the American Nations – from jayman.

Privilege and Morality“Our species isn’t good at nuance. The ‘privilege’ debate will and must take place in a morally charged context. It is not possible to sanitize the discussion by scrubbing it free of moral emotions. That is one of the many reasons why it is so important to understand what morality is and why it exists. It does not exist as a transcendental entity that happened to pop into existence with the big bang, nor does it exist because the Big Man upstairs wants it that way. It exists because it evolved.” – from helian.

Economic Growth & Human Biodiversity“Economic growth in lower-IQ countries does not invalidate either the reality of IQ differences between countries or the persistence of those disparities.” – from pseudoerasmus.

Good Fences: The Importance of Setting Boundaries for Peaceful Coexistence“Switzerland is recognized as a country of peace, stability and prosperity. This is surprising because of its linguistic and religious diversity that in other parts of the world lead to conflict and violence. Here we analyze how peaceful stability is maintained. Our analysis shows that peace does not depend on integrated coexistence, but rather on well defined topographical and political boundaries separating groups, allowing for partial autonomy within a single country. In Switzerland, mountains and lakes are an important part of the boundaries between sharply defined linguistic areas. Political canton and circle (sub-canton) boundaries often separate religious groups. Where such boundaries do not appear to be sufficient, we find that specific aspects of the population distribution guarantee either sufficient separation or sufficient mixing to inhibit intergroup violence according to the quantitative theory of conflict. In exactly one region, a porous mountain range does not adequately separate linguistic groups and that region has experienced significant violent conflict, leading to the recent creation of the canton of Jura.”

Was Territoriality Important in the Pleistocene? A Commentary on Johnson and Toft – @peter turchin’s.

Southern Europe is suspicious: the evolution of trust in the EU – ess and wvs results.

Trust and In-Group Favoritism in a Culture of Crime [pdf] – h/t ben southwood! who tweeted: “Areas in Palermo with high Mafia involvement have lower generalised trust but higher in-group favouritism.”

In dogs’ play, researchers see honesty and deceit, perhaps something like morality – woof!

What is Phonemic Diversity? — And Does It Prove the Out-of-Africa Theory? – h/t james winters!

How a Protestant spin machine hid the truth about the English Reformation“It seems that in 1533, the year of Henry’s break from Rome, traditional Catholicism was the religion of the vast majority of the country. And in most places it was absolutely thriving. It had developed a particularly English flavour, with a focus on the involvement of ordinary people in parish churches, village greens, plays, and pageants – much of which seemed to involve a good deal of community parties, dancing, and drinking. It is true that English religion in the early 1500s was not especially studious or erudite. The people did not spend hours a day in biblical studies, contemplation, and moralising in the manner of the more intense European reformers. But England had a nationally cohesive spirituality that was alive and exuberant, with a distinctly community feel…. The conclusion of this modern grassroots scholarship is that bulldozing the Catholic Church off the face of medieval England was not a ‘bottom up’ revolution in which Henry merely acquiesced to his people’s wishes by throwing off a widely hated foreign domination. To the contrary, it looks increasingly like Henry and his circle imposed the Reformation ‘top down’, unleashing 100 years of deep anger and alienation that was only overcome by sustained politicking and ruthless force.” – h/t william briggs!

bonus: “No Oxygen? No Problem!” Says Squid That Can Shut Down Its Metabolism – h/t kyle hill!

bonus bonus: A Theory on How Flightless Birds Spread Across the World: They Flew There

bonus bonus bonus: Chicken project gets off the ground“Effort aims to unravel the history of bird’s domestication.” – cluck!

(note: comments do not require an email. humble humboldt squid!)

Calcium absorption not the cause of evolution of milk digestion in Europeans“‘The evolution of lactase persistence is one of the best known and most dramatic examples of recent human evolution. One of the ironies of working in this area is that we know it happened but we still don’t fully know why’ says Sverrisdóttir. Lactase persistence is found at highest frequencies in southern Sweden and in Ireland. Given that calcium absorption is not the only reason why this trait evolved so rapidly, Sverrisdóttir and colleagues have proposed another cause: Although most early European farmers would not have been lactase persistent, they would still have been able to consume fermented milk products such as yoghurt and cheese, because fermentation converts much of the lactose into fats. But in famine conditions, such as when crops fail, they are likely to have eaten all the fermented milk foods, leaving only the more high-lactose products. This would have caused the usual lactose intolerance symptoms such as diarrhea. Diarrhea in in healthy people is not usually life-threatening, but in severely malnourished individuals it certainly can be. So famine could have led to episodes of very strong natural selection favoring lactase persistence.”

Human and Helicobacter pylori coevolution shapes the risk of gastric disease“Patients were recruited from two geographically distinct Colombian populations with significantly different incidences of gastric cancer, but virtually identical prevalence of H. pylori infection. All H. pylori isolates contained the genetic signatures of multiple ancestries, with an ancestral African cluster predominating in a low-risk, coastal population and a European cluster in a high-risk, mountain population. The human ancestry of the biopsied individuals also varied with geography, with mostly African ancestry in the coastal region (58%), and mostly Amerindian ancestry in the mountain region (67%). The interaction between the host and pathogen ancestries completely accounted for the difference in the severity of gastric lesions in the two regions of Colombia. In particular, African H. pylori ancestry was relatively benign in humans of African ancestry but was deleterious in individuals with substantial Amerindian ancestry. Thus, coevolution likely modulated disease risk, and the disruption of coevolved human and H. pylori genomes can explain the high incidence of gastric disease in the mountain population.”

Seeing X Chromosomes in a New Light“X-chromosome inactivation, Dr. Nathans’s pictures show, creates a genetic diversity that’s particularly dramatic. Two cells side by side may be using different versions of many different genes. ‘But there is also much larger-scale diversity,’ Dr. Nathans said. In some brains, for example, a mother’s X chromosome was seen dominating the left side, while the father’s dominated the right. Entire organs can be skewed toward one parent. Dr. Nathans and his colleagues found that in some mice, one eye was dominated by the father and the other by the mother. The diversity even extended to the entire mouse. In some animals, almost all the X chromosomes from one parent were shut; in others, the opposite was true.”

Are plants altruistic?“Roots can distinguish self from other, and they know their own kind (species), they can share resources and information about insect attacks and deliver nutrients to trees in need. The preponderance of evidence does seem to suggest that plants are proactive in filling their own needs and the needs of others.” – ooooh, not just their own species, their own close relatives! – see also The Intelligent Plant.

Sluggish metabolisms are key to primates’ long lives“[P]rimates expend 50 per cent less energy than other mammals of equivalent mass during an average day. ‘What’s more, he says the difference is not easily explained by differing activity levels: a human would need to run a whole marathon every day to be on an even energetic footing with mammals that aren’t primates….’ The finding offers a completely new way to understand why primates have slower life histories than other mammals of equivalent body size…. Pontzer thinks that the slower metabolism may have evolved to help primates cope with food shortages. For instance, orang-utans suffer frequent famines. ‘Orang-utans experience extended periods of low fruit availability,’ says Vogel. ‘There are months when caloric intake is less than expenditure – and they burn body fat stores.’ A slow metabolism might help them survive.”

Triune origins“With the latest paper, the story on European origins is becoming clearer. Three populations account for European ancestry: the Mesolithic hunter-gatherers of western Europe (dubbed WHG in the paper), early European farmers derived from somewhere in the Mideast (EEF), and a third group more closely related to ancient Siberians (ANE) than any existing population. Those Sibermen also contributed a third of Amerindian ancestry, the rest being similar to modern East Asian populations.” – from greg cochran.

The first industrial revolution“As early modern humans spread farther north, they entered more challenging environments…. Did these new cognitive demands have an evolutionary impact? Did they select for certain mental capacities over others? Piffer (2013) has addressed these questions by seeing how hunter-gatherers differ from farming peoples in alleles at COMT, a gene linked to executive function, working memory, and intelligence…. Northern hunting peoples, however, differ from other hunter-gatherers and resemble more advanced farming populations.” – from peter frost.

‘Out of Africa’ gene mutation in human pigmentation increases predisposition to skin cancer“The V60L mutation is more common in people with light hair and skin tone that, despite being light, tans easily in the summer. This mutation is positive for the climate of the Mediterranean region, as it facilitates the absorption of vitamin D in the winter months, in which the ultraviolet radiation is lower. In the summer months, in which the radiation is greater, the ease to darken the skin pigmentation provides a certain protection. However, the study also revealed that among people with this mutation there is a greater predisposition to skin cancer.” – see also: Simultaneous Purifying Selection on the Ancestral MC1R Allele and Positive Selection on the Melanoma-Risk Allele V60L in South Europeans.

Longitudinal four-dimensional mapping of subcortical anatomy in human development – h/t kevin mitchell! who said: “Large imaging study details substantial sex differences in maturation dynamics of subcortical structures.” – also: Fundamental sex difference in human brain architecture [behind paywall].

Changes in Thickness and Surface Area of the Human Cortex and Their Relationship with Intelligence“At 10 years of age, more intelligent children have a slightly thinner cortex than children with a lower IQ. This relationship becomes more pronounced with increasing age: with higher IQ, a faster thinning of the cortex is found over time. In the more intelligent young adults, this relationship reverses so that by the age of 42 a thicker cortex is associated with higher intelligence. In contrast, cortical surface is larger in more intelligent children at the age of 10. The cortical surface is still expanding, reaching its maximum area during adolescence. With higher IQ, cortical expansion is completed at a younger age; and once completed, surface area decreases at a higher rate. These findings suggest that intelligence may be more related to the magnitude and timing of changes in brain structure during development than to brain structure per se, and that the cortex is never completed but shows continuing intelligence-dependent development.”

Why do spatial abilities predict mathematical performance?“About a third of the variation in spatial ability at age 12 is explained by genetic factors; a little less than half of the variation in mathematics at this age is genetic. We find no sex differences in the genetic and environmental influences (either in magnitude or type) on mathematical and spatial variation at age 12. The observed overlap between spatial ability and mathematics is substantial (r > .40). Approximately 60% of this overlap is explained by common genetic effects, with 40% of the overlap due to environmental experience.” – h/t DOCTOR stuart ritchie! (^_^)

New evidence shows the FDA was wrong to halt 23andMe testing“While the tests are often too inaccurate for consumers to consider them diagnoses, research shows that most customers will seek a doctor’s opinion before taking action, anyway. According to the authors’ research, 58% of 1,051 surveyed customers did nothing at all with their genomic results. Of the 42% who made health decisions based on the information, only 2% changed prescription drug regimens without consulting a physician. The majority of customers who made changes focused on diet, exercise, and vitamins.”

Dogs’ Closest Wolf Ancestors Went Extinct, Study Suggests” A new genetic analysis of modern dogs and wolves suggests that man’s best friend was domesticated before agriculture. But the origin of this domestication remains stubbornly mysterious. Researchers analyzed the genomes of wolves from three likely sites of domestication (the Middle East, Asia and eastern Europe), and found that modern dogs were not more closely related to any of the three. In fact, it seems that the closest wolf ancestors of today’s dogs may have gone extinct, leaving no wild descendants.” – also: Paedomorphic Facial Expressions Give Dogs a Selective Advantage – woof! – h/t claire lehmann!

The Nurture Enigma – How Does the Environment Influence Human Nature? – from staffan.

The interplay of genetic and cultural evolution – from jason collins.

Eye of the Tiger PeopleBut what the hell is ‘culture,’ anyway? Talk about a social construct! Even the term ‘social construct’ is a social construct, one unique to our culture. And who’s to say culture is entirely separate from genetics? There’s some suggestion that the two may be intimately intertwined. In rawest terms, ‘culture’ may be nothing more than what happens when a group’s genes interact with their environment. – from jim goad.

Toddlers’ aggression is strongly associated with genetic factors, study reports“The development of physical aggression in toddlers is strongly associated genetic factors and to a lesser degree with the environment, according to a new study led by Eric Lacourse of the University of Montreal and its affiliated CHU Sainte-Justine Hospital. Lacourse’s worked with the parents of identical and non-identical twins to evaluate and compare their behaviour, environment and genetics.” – h/t mr. mangan, esq!

Modifying DNA May Wipe Away Old Memories – so can several double gin and tonics in a row. (~_^) – they’re talking about epigenetic changes here, btw.

Apes are intuitive statisticians“Here, we conducted the first investigation of such intuitive statistical reasoning with non-human primates. In a series of 7 experiments, Bonobos, Chimpanzees, Gorillas and Orangutans drew flexible statistical inferences from populations to samples. These inferences, furthermore, were truly based on statistical information regarding the relative frequency distributions in a population, and not on absolute frequencies. Intuitive statistics in its most basic form is thus an evolutionarily more ancient rather than a uniquely human capacity.” – iow, the other great apes outperform a lot of humans (i.e. the pc ones)! (~_^) – h/t neuroskeptic!

Study: Chimpanzees Bond Over Shared Meals“[C]himps who share their food have higher levels of oxytocin, known as the love hormone, than those who don’t.” – h/t hbd bibliography!

Comedians have psychotic personality traits, study finds“In a study in the British Journal of Psychiatry, researchers analyzed comedians from Australia, Britain and the United States and found they scored significantly higher on four types of psychotic characteristics compared to a control group of people who had non-creative jobs. The traits included a tendency towards impulsive or anti-social behavior, and a tendency to avoid intimacy. ‘The creative elements needed to produce humor are strikingly similar to those characterizing the cognitive style of people with psychosis – both schizophrenia and bipolar disorder,’ said Gordon Claridge of the University of Oxford’s department of experimental psychology, who led the study.”

Natural selection can favour ‘irrational’ behaviour – well, there’s your problem!

‘Human evolution likely led to rise of religion’ – h/t holly dunsworth! whose response was: duh! (~_^)

New study finds mistimed sleep disrupts rhythms of genes in humans“During this disruption of sleep timing, there was a six-fold reduction in the number of genes that displayed a circadian rhythm (a rhythm with an approximately 24 hour period). This included many regulators associated with transcription and translation, indicating widespread disruption to many biological processes.” – sleep right!

speaking of which: Study finds later school start times improve sleep and daytime functioning in adolescents – h/t anatoly!

The human brain can process images the eye sees for 13 milliseconds – imagine how quickly THE FLASH’s brain can process images!! (~_^)

The Islamic Republic of Baby-Making“Iran, like other Middle Eastern countries, has an extremely high infertility rate. More than 20 percent of Iranian couples cannot conceive, according to a study conducted by one of the country’s leading fertility clinics, compared with the global rate of between 8 and 12 percent. Experts believe this is due to the prevalence of consanguineous marriages, or those between cousins. Male infertility is ‘the hidden story of the Middle East,’ says Marcia Inhorn, a Yale University medical anthropologist and a specialist on assisted reproduction in the region.”

This Language Names Odors As Precisely As English Speakers Name Colorjahai speakers in malaysia. – h/t t.greer! – see also: Can You Name That Smell?“It’s also possible that the Jahai are built differently than the rest of us. The genes that code for the olfactory receptors in our noses exhibit a great deal of variation not only between different human populations but also between people. So it may be that the Jahai have evolved more of these receptors or a greater diversity of them than everyone else, much like the Tsimane tribe from the Bolivian rainforest were shown to be more sensitive to smells than were Germans.”

Gene therapy ‘could be used to treat blindness’“Surgeons in Oxford have used a gene therapy technique to improve the vision of six patients who would otherwise have gone blind. The operation involved inserting a gene into the eye, a treatment that revived light-detecting cells.”

The thinnest Americans are Asian Americans, CDC data show – surprise!

Shapely centrefolds? Temporal change in body measures: trend analysis – h/t ben southwood! who said: “Playboy centrefolds’ waists have widened, weights have fallen, busts have shrunk and hips have narrowed since 1953.”

Study: Violence, infectious disease and climate change contributed to Indus civilization collapse – h/t mike anissimov!

What was in that grog? Scientists analyze ancient Nordic drink“Ancient Scandinavians quaffed an alcoholic mixture of barley, honey, cranberries, herbs and even grape wine imported from Greece and Rome, new research finds.” – mmmmmm! mmmmmm?

bonus: i’m a journalist! – h/t jayman!

bonus bonus: and a neo-fascist, too, apparently. hahahahahahahaha!! *snort*

bonus bonus bonus: Genetically engineered plant glows so brightly it can be used as a LAMP

(note: comments do not require an email. memory erasers.)

Capturing a Hard-Wired Variability: What Makes Some Identical Twins Noticeably Different?“The current study finds that only one allele is expressed in between 12 and 24 percent of all such pairs encoded by the mouse genome. Further, the selection of expressed alleles varies randomly from cell to cell, and switches frequently between the two options throughout their lives…. ‘We find that for those genes that are not imprinted, roughly one in five alleles is randomly and dynamically expressed only one at a time,’ says Sandberg. ‘And if one allele is being expressed, the other doesn’t know about it. There’s no coordination between two.'”

meanwhile: Identical twins need never be tried for same crime after DNA breakthrough“Cases of identical twins being tried for the same crime may never happen again after a scientific breakthrough found there are subtle differences in their DNA.” – h/t Big Daddy Jayman!

Indigenous Groups More Vulnerable in Fight Against Flu“Research indicated that some Indigenous people such as in Alaska and Australia displayed limited immunity response to the effects of influenza.” – h/t hbd bibliography!

Islands make animals tamer“Lizard study supports Darwin’s hunch that lack of predators leads to unwatchful behaviour.” – hmmmm.

A Living Time Capsule Shows the Human Mark on Evolution“Scientists have revived shrimp-like animals that have been buried at the bottom of the lake for an estimated 700 years. If this estimate holds up to further testing, they are the oldest animals ever resurrected…. The oldest DNA the scientists obtained from the lake dates back to around the time the Vandals were ransacking Rome. The scientists found that one genetic strain of water fleas dominated at the time — and continued to until the late 1800s. As phosphorus [from fertilizers] flooded the lake, a previously rare strain emerged and took over.”

Evolution Hidden in Plain Sight“One of the hallmarks of *Escherichia coli* as a species is that when there’s oxygen around, it can’t feed on a compound called citrate. But one day a flask turned cloudy with an explosion of *E. coli* that were doing just that. The change was so profound that it may mean these bacteria had evolved into a new species.”

SLC24A5 light skin pigmentation allele origin“‘The distributions of C11 and its parental haplotypes make it most likely that these two last steps occurred between the Middle East and the Indian subcontinent, with the A111T mutation occurring after the split between the ancestors of Europeans and East Asians.'” – @dienekes’.

The brown man with blue eyes“Interestingly, although the Luxembourg man was blue-eyed, he also had brown skin. He lacked the ‘European’ alleles at all three genes involved in the whitening of European skin.” – from peter frost.

Factor Analysis of Population Allele Frequencies as a Simple, Novel Method of Detecting Signals of Recent Polygenic Selection: The Example of Educational Attainment and IQ [pdf] – “Frequencies of 10 SNPs found to be associated with educational attainment in a recent genome-wide association study were obtained from HapMap, 1000 Genomes and ALFRED. Factor analysis showed that they are strongly statistically associated at the population level, and the resulting factor score was highly related to average population IQ (r=0.90). Moreover, allele frequencies were positively correlated with aggregate measures of educational attainment in the population, average IQ, and with two intelligence increasing alleles that had been identified in different studies.” – h/t elijah! see also jayman.

Ancient hunter-gatherers had rotten teeth“Scientists have long thought that tooth decay only became common in humans about 10,000 years ago, when we began farming – and eating starchy crops that fed sugar-loving bacteria on our teeth. But Isabelle De Groote of the Natural History Museum in London, UK, and her colleagues have found widespread tooth decay in hunter-gatherers that lived several thousand years before the origin of agriculture.”

The Liberal Illusion of Uniqueness“[L]iberals underestimate their similarity to other liberals (i.e., display *truly false uniqueness*), whereas moderates and conservatives overestimate their similarity to other moderates and conservatives (i.e., display *truly false consensus*…).” – h/t ben southwood!

More complex brains are not always better: rats outperform humans in implicit category-based generalization by implementing a similarity-based strategy – in some ways, rats are smarter than you. (~_^) – h/t ben southwood!

Why Are Some Types of People More At Risk of Schizophrenia Than Others? – from chris davies.

Is and Ought – from henry harpending.

US Army Ambushed by Toxic Leaders and Toxic Leaders And The Social Environments That Breed Them – psychopaths?

Is the dark side of parenting genetic?“In a novel finding, Robert Plomin and colleagues suggest that negative aspects of parenting are more heritable than positive aspects. They call this The Dark Side of parenting. The effect is interesting and subtle: it suggests that whilst parents are generally consistent in their handling of their children, some genetically driven characteristics of their children lead them into more negative parenting styles…. In simple terms, even peaceable parents get irritable with difficult children.” – from dr. james thompson.

Ancient times table hidden in Chinese bamboo strips“The 2,300-year-old matrix is the world’s oldest decimal multiplication table.”

Unthinkable: Who’s running the show, you or your brain?“The question of whether the brain is paramount has profound implications for all of us.” – interview w/kevin mitchell.

Hunter–gatherers have less famine than agriculturalists – h/t richard harper!

Changelings, Infanticide and Northwest European Guilt Culture“To summarize, the changeling lore provides evidence of a NWE guilt culture dating back at least to medieval times, and the practice and attitude towards exposure suggests that ancient Greece had an emerging guilt culture as early as the 400s BC which enabled a similar individualism and intellectual development that we’ve seen in the NWE in recent centuries.” – from staffan.

IamA 15 (nearly 16)-year-old who has co-written a peer-reviewed paper on intelligence. AMA!elijah armstrong‘s reddit ama! (^_^) (keep in mind that most redditors are idiots. except the ones on r/starwars, of course.)

This is what a beta looks like – from the awesome epigone. hbd-babies everywhere! (^_^)

Ancient cholera mysteriously disappeared“Strains that plagued Europe and the United States in the nineteenth century were distinct from those prevalent today.”

The social animal“Whether in education, ethics or politics, we ignore our social natures at our peril.”

2,000-year-old skeleton unearthed in Davie – in florida – h/t charles mann!

Bullied and Badgered, Pressured and Purged – list of the pc-incorrect who have been witch-hunted @handle’s haus.

bonus: The manosphere goes gaga for this woman – the blue pill people don’t like me. they’re prolly just jealous. (~_^)

bonus bonus: Is A Blubbering Inner Party Leftoid Trying To Silence Chateau Heartiste? – the best defense is a good offense!

bonus bonus bonus: Mysterious Microscopic Bubbles Baffle Ocean Scientists“The most abundant photosynthetic organism in the world [cyanobacteria] sheds countless little sacs into the oceans, which could be having a dramatic impact on marine ecosystems, according to a new study. These microbial buds contain proteins and genetic material, which may influence the growth of other marine microbes and even protect them against viruses.”

bonus bonus bonus bonus: Video: Fish leaps to catch birds on the wing“Tigerfish swallows swallows after grabbing them out of the air over African lake.” – holy cr*p!

bonus bonus bonus bonus bonus: Dogs Relieve Themselves In-Line With Earth’s Magnetic Field“Dogs are quite particular about where they choose to relieve themselves — not only do they defecate in direction with the north-south axis, but they also are sensitive to slight changes in the Earth’s magnetic field.”

bonus bonus bonus bonus bonus bonus: War Elephant Myths Debunked by DNA“Until now, the main question remained: Did Ptolemy employ African savanna elephants (*Loxodonta africana*) or African forest elephants (*Loxodonta cyclotis*) in the Battle or Raphia? ‘Using three different markers, we established that the Eritrean elephants are actually savanna elephants….'”

bonus bonus bonus bonus bonus bonus bonus: Actual Academic Journals Which Could Be Broadway Shows If They Had Exclamation Points Added!

bonus bonus bonus bonus bonus bonus bonus bonus: Science Apologizes to Little Girl for Not Making Dragons – and so they should!!

(note: comments do not require an email. tigerfish. holy cr*p!)

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