Archives for posts with tag: surrogate mothers

oops! it happened again. =/

Deletion of Any Single Gene Provokes Mutations Elsewhere in the Genome“Johns Hopkins researchers report that the deletion of any single gene in yeast cells puts pressure on the organism’s genome to compensate, leading to a mutation in another gene…. ‘The deletion of any given gene usually results in one, or sometimes two, specific genes being “warped” in response….'”

Self-heal like Wolverine? Gene discovery might hold clues“In a discovery by a Harvard researcher, a reactivated gene found in embryos helps mice regrow clipped parts of their ears and toes. Could the ‘fountain of youth’ gene hold promise for humans too?” – i want one! – h/t mike anissimov!

Gene Variants Up CKD [chronic kidney disease] Risk in Blacks“A high-risk genetic variant conferred a significantly increased risk of progressive kidney disease in African Americans, at least partly explaining a racial disparity in end-stage renal disease (ESRD), investigators reported here. Analysis of black and white patients in another trial — half with diabetes — showed kidney function declined almost three times as fast in blacks with the high-risk APOL1 profile as compared with whites….”

Genetic clue to high heart risk of black Americans“The gene that produces the protein [PC-TP which activates a clotting factor called PAR4] is four times more active in the platelets of black Americans than it is in white Americans.” – h/t hbd bibliography!

Europeans and South Asians share by descent SLC24A5 light skin allele“‘We date the coalescence of the light skin associated allele at 22–28 KYA. Both our sequence and genome-wide genotype data confirm that this gene has been a target for positive selection among Europeans. However, the latter also shows additional evidence of selection in populations of the Middle East, Central Asia, Pakistan and North India but not in South India.'” – @dienekes’.

The ancestors with no descendants“On the eve of the last ice age, Siberia was home to a people who were related to modern Europeans and Amerindians but not to modern native Siberians. So concludes an analysis of DNA from the remains of a boy who lived 24,000 years ago at Mal’ta near Lake Baikal, Siberia…. [T]he Mal’ta people probably looked very much like native Indians with a more European skull shape, perhaps like the Ainu of northern Japan or the Kennewick humans of North America.”

Political colour is half genetic“New study provides definitive evidence that heritability plays a significant role in the formation of political ideology, regardless of how ideology is measured, the time period or population sampled.” – @ScienceNordic.com – the photo caption is pretty funny/telling: “Imagine if scientists could identify the ‘liberal’ genes and genetically modify babies so that they all voted liberal when they grow up? Brave new world?” (and the first comment is priceless!) – h/t ray sawhill!

It’s not just conservatives that support discrimination against their ideological foes“‘Discrimination by liberals has received scant attention in the literature, despite this being a prevalent concern in conservative rhetoric. By only examining conservative biases, social scientists fail to fully explore political intolerance in America. This research helps fill that gap….’ When opposing groups were seen as violating core values, liberals were just as likely to support discrimination against same-sex marriage opponents, religious fundamentalists, Tea Party protestors, and prolife people as were conservatives against feminists, atheists, leftist protestors, and prochoice people.”

Politics Has an Odor“[C]onservatives are significantly more likely than liberals to detect [bitter tasting] PTC [phenylthiocarbamide].” – h/t jayman!

Study: Your brain sees things you don’t“Our brains perceive objects in everyday life of which we may never be aware, a study finds, challenging currently accepted models about how the brain processes visual information.”

New evidence on the biological basis of highly impulsive and aggressive behaviors“Physical and chemical changes in the brain during development can potentially play a role in some delinquent and deviant behaviors.”

Root of maths genius sought“Entrepreneur’s ‘Project Einstein’ taps 400 top academics for their DNA.”

Has a 15-year-old explained the Flynn Effect? – on elijah amstrong and michael woodley’s newly published paper! – from steve sailer.

Is young Woodley down for the count? – never! (^_^) – from dr. james thompson.

Religions of the American Nations“[T]hese differences [regional cultural and political divisions in america] stem from the *genetic* differences in the descendants of these initial settlers (suffused with the genes of subsequent immigrants, particularly in the old North).” – from jayman.

In Hookups, Inequality Still Reigns“[A] study of 24,000 students at 21 colleges over five years found that about 40 percent of women had an orgasm during their last hookup involving intercourse, while 80 percent of men did.” – h/t john durant!

The Co-Villains Behind Obesity’s Rise“Not everyone, however, has the same gut bacteria. And, interestingly, the composition of this bacteria correlates with obesity…. [T]he bacteria study found that the ‘obese gut bacteria’ had an impact only when the mice were fed diets heavy in saturated fats.” – h/t jayman!

Rich Chinese Couples Turning To American Surrogates For Easier Immigration And ‘Designer Babies’“Another factor that has some Chinese couples choosing American surrogates is a desire for ‘designer babies.’ While most couples still use their own eggs and sperm, making the child biologically theirs, Reuters reports that more and more people are open to egg donation, to get what some clients believe are smarter and better-looking children. ‘Lots of clients that are Chinese do use tall, blond donors,’ Jennifer Garcia, who works at Extraordinary Conception in California, where 40 percent of clients are Chinese, said in the report.” – h/t mark krikorian!

CRISPR gene therapy: Scientists call for more public debate around breakthrough technique“‘I’m sure there will be some concern about the possibility that the technology could be used for “enhancement” rather than repair, veering from medicine towards eugenics,’ [professor wells] warned.” – oh noes! not “enhancement”! *swoon!* h/t anatoly!

Should state education be abolished?“New York City adopting Finland’s education system is not going to make New York like Finland…. In the game of life the dice are loaded and trying to make teachers responsible for making life fair is deluded and unfair to them….” – from ed west.

Shaker Heights – from greg cochran.

John Derbyshire’s Modest Proposal On Politics and Intelligence“And the too-dumb-to-vote segment is only a part of the problem we conservatives have with universal suffrage. Here’s another part: too *smart* to vote…. At the very highest levels of intelligence, the correlation between IQ and sensible political opinions may actually be *inverse*: the more brilliant you are, the dumber your politics. Albert Einstein thought well of Stalin; Hitlerism got its first mass following in the highly-selective German universities.”

Amid austerity and debt, Denmark remains happiest nation“The second pillar of happiness is a high level of trust between people, even for a stranger on the street….” – crazy danes! (~_^)

Introducing the Mongol Project“‘I will now tell you all about the Tartars and how they acquired their empire and spread throughout the world.'” – excellent! – from t.greer.

Early uses of chili peppers in Mexico“Chili peppers may have been used to make spicy beverages thousands of years ago in Mexico….”

Case of Insect Interruptus Yields a Rare Fossil Find“[T]he oldest fossil of two insects copulating.” – 165 million years old!

This Is How Much Money You’ll Make Based on Your Personality – d*mn. =/

bonus: Another Word for “Holocaust”“[O]ne would have to be smoking banana peels dipped in formaldehyde and sprinkled with PCP to assert that both events [the holocaust and the holodomor] receive a similar amount of attention in Western media and academia.” – from jim goad. of course.

bonus bonus: Swedish cinemas launch feminist movie rating – hahahahahaha!!! heh. wait. (*hbd chick wipes tears from eyes*) heh. – “To get an ‘A’ rating, a movie must pass the so-called Bechdel test, which means it must have at least two named female characters who talk to each other about something other than a man….” – hahahahahaha!! – “The entire ‘Lord of the Rings’ trilogy, all ‘Star Wars’ movies, ‘The Social Network,’ ‘Pulp Fiction’ and all but one of the ‘Harry Potter’ movies fail this test,” – so, except for The Social Network, all of my faves. this is going to be a REALLY handy movie rating system. whatever movies they FAIL, i will go see! (^_^)

bonus bonus bonus: Strange Doings on the Sun“Sunspots, Which Can Harm Electronics on Earth, Are Half the Number Expected” – ruh roh.

bonus bonus bonus bonus: Large magma reservoir gets bigger – ruh roh.

bonus bonus bonus bonus bonus: This amazing fruit fly evolved to have pictures of ants on its wings – srsly! – h/t jayman!

(note: comments do not require an email. rupee – first dog to climb mt. everest. woof!)

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Ancient DNA Links Native Americans With Europe“…from the complete nuclear genome of a Siberian boy who died 24,000 years ago — the oldest complete genome of a modern human sequenced to date. His DNA shows close ties to those of today’s Native Americans. Yet he apparently descended not from East Asians, but from people who had lived in Europe or western Asia. The finding suggests that about a third of the ancestry of today’s Native Americans can be traced to ‘western Eurasia,’ with the other two-thirds coming from eastern Asia…. It also implies that traces of European ancestry previously detected in modern Native Americans do not come solely from mixing with European colonists, as most scientists had assumed, but have much deeper roots.” — see also: The First of the Mohicans from greg cochran.

Your face may have been sculpted by junk DNA“There is a huge degree of variation in human faces but, as family resemblances show, the overall shape is heavily constrained by genetics. However, so far, geneticists have identified only a small number of genes that influence the shape. These explain just a tiny fraction of the variation seen in human faces. According to Axel Visel of the Lawrence Berkeley National Laboratory in California and his colleagues, more variation is controlled by distant-acting enhancers. These are short sequences of DNA, in non-coding regions of the genome, that can influence the activity of the facial genes, even if they are a long way along the DNA strand.”

Behavior problems in preschool and child care centers may be an issue of genes“A new study suggests that some children may be genetically predisposed to developing behavioral problems in child care and preschool settings…. [B]irth parents who had high rates of negative emotion and self-control, based on a self-reported temperament scale, were more likely to have children who struggled with behavioral issues such as lack of self-control and anger, in child care centers. They controlled for adoptive parent’s characteristics, and still found a modest effect based on the genetic link.”

Your Ethnicity Determines the Species of Bacteria That Live in Your Mouth“[P]eople from each of the four different ethnic groups represented in the study (all participants self-identified as either Caucasian, African-American, Chinese or Latino) generally had similar species of bacteria, especially underneath the gums. As a result, simply by counting which varieties of bacteria appeared in this area, the researchers developed a model that was able to guess a person’s ethnicity with an accuracy significantly better than chance — it got it right 62 percent of the time. Some groups were even easier to identify via the bacteria than others: It could correctly identify Latinos 67 percent of the time and African-Americans with 100 accuracy. The variation along ethnic lines, they believe, is a reflection of genetics, not environment. That’s because, if you assumed that the mouth microbiome is totally dependent on environmental factors, you’d expect that members of the same ethnic group would have different mixes of bacteria depending on whether they were first-generation immigrants to the U.S. or had family histories that stretched back generations in the country. Instead, people’s background — in terms of foods they ate and other lifestyle trends — didn’t seem to have any correlation with the bacterial communities in their mouths. – h/t super bob!

Herpes virus genome traces the ancient path of human migration“Researchers…sequenced the genomes of 31 samples of herpes simplex virus type-1 to reconstruct how it hitchhiked on humans as they dispersed around the world. The results match the pattern proposed by the ‘Out of Africa’ theory, which has become the most widely accepted scenario for ancient human migration. The analysis showed that African strains of the virus contained the most genetic diversity — suggesting that they had the oldest roots.”

Genetic variation alters efficacy of antidepressant“Having a different form of a gene that regulates the brain chemical noradrenaline influences how well men remember negative memories after taking the antidepressant drug reboxetine, according to a study published in the October 23 issue of The Journal of Neuroscience. The findings demonstrate how genes can influence antidepressant response.” – see also: Genes predispose some people to focus on the negative.

Much Earlier Split for Neanderthals, Humans?“This suggests that the last common ancestor of H. sapiens and Neanderthals lived sometime earlier, perhaps as far back as one million years ago.”

Denisovans in Wallacea? – from greg cochran.

Life on Earth Was Not a Fluke“Figuring out how biomolecular self-organization happens may hold the key to understanding life on Earth formed and perhaps how it might form on other planets.” – h/t jayman!

Genetics made very simple – from dr. james thompson.

Low historical rates of cuckoldry in a Western European human population traced by Y-chromosome and genealogical data“[W]e estimate that over the last few centuries, EPP rates in Flanders (Belgium) were only around 1–2% per generation. This figure is substantially lower than the 8–30% per generation reported in some behavioural studies on historical EPP rates, but comparable with the rates reported by other genetic studies of contemporary Western European populations. These results suggest that human EPP rates have not changed substantially during the last 400 years in Flanders and imply that legal genealogies rarely differ from the biological ones.” – h/t rob brooks!

‘Endowment Effect’ Not Present in Hunter-Gather Societies“‘The more isolated Hadza traded about 50 percent of the time — which is what rational people should do,’ Azevedo said. People near the village traded about 25 percent of the time, which is much closer to the 10 percent we see with Western students.” – h/t jason collins! – previously: personality goes a long way… in which researchers find just big TWO personality traits in a group of hunter-gatherers (the tsimane).

speaking of the tsimane: UCSB anthropologist studies the evolutionary benefit of human personality traits“‘Being more extroverted, open, agreeable and conscientious –– and less neurotic –– was associated with having more kids.'” in tsimane men. (if they really have all those personality traits…see link immediately above.)

What Happens When a Language Has No Numbers? – on the pirahã. – h/t nn!

Can Your Genes Predict Whether You’ll Be a Conservative or a Liberal?“Scientific research shows political partisanship transcends economics, environment, and upbringing.” – from avi tuschman.

Life expectancy and the dawn of agriculture – from jason collins.

Origins of Americans (Looking At HLA Haplotypes) – from our very own chris davies! previously from chris: human leukocyte antigen (hla) haplotypes and human biodiversity.

Number sense in infancy predicts mathematical abilities in childhood“Preverbal number sense in 6-month-old infants predicted standardized math scores in the same children 3 years later. This discovery shows that number sense in infancy is a building block for later mathematical ability and invites educational interventions to improve number sense even before children learn to count.” – h/t simon baron-cohen!

Black Suits, Gowns, & Skin: SAT Scores by Income, Education, & Race – @the unsilenced science. see also: Obama Administration: Moynihan’s Law of Canadian Border kinda right from steve sailer.

Of Race and Intelligence – from helian.

Sex on the Mind“It is a truth universally acknowledged — at least by biologists — that every person owes his or her existence to parents who successfully reproduced, each of whom, in turn, had two parents who did the same … and so on, going back hundreds of millions of years to the first ancestral blob (or two) of protoplasmic goo that trundled onto terra firma from the early earth’s organic soup.” – from david barash. — see also: Why Have Sex? – from the advanced apes.

Lust Is Love – from heartiste.

Kids Are More Likely to Trust Attractive Adults – h/t hbd bibliography!

Asymmetries in altruistic behavior during violent intergroup conflict“Some empirical studies on intergroup conflict in hunter-gatherer societies and chimpanzees indicate that fitness relevant risks and potential benefits of attacks and defenses might have differed substantially under ancestral conditions. Drawing on these studies, it is hypothesized that the success of defenses was much more important for individual and kin survival and that a disposition to act altruistically during intergroup conflict is thus more likely to evolve for the strategic situation of defense…. Analyzing detailed historical case data from 20th century wars, this study finds that altruistic behavior towards members of the in-group indeed seems to occur more frequently when soldiers are defending themselves and their comrades against enemy attacks.” – h/t hbd bibliography!

Who gives? Multilevel effects of gender and ethnicity on workplace charitable giving.“[E]thnic minorities donate less money to workplace charity than do Whites.” – and men less than women. – via richard lynn @amren.

Paradoxes of the Nordic Model II“Denmark is a high trust, highly cooperative society. There is very low crime. Most parked bicycles are not even locked. Bank employees may not work very efficiently, but nobody tried to swindle me. In theoretical terms, what it means is that when there are very few defectors, the amount of common good produced overall is maximized. So everybody is well of, even though they don’t work hard – but they don’t free-ride, either….” – from peter turchin.

Ma’am, Your Burger Has Been Paid For – paying it forward in america! – h/t charles murray!

Napoleon Chagnon: The Fierce Sociobiologist“[Yanomamo] Men from the highland villages were much less belligerent than men from villages along the river. Heterogeneity in belligerence existed even within this single tribe.”

Where Have All the Geniuses Gone?

Aboriginal Hunting Practice Increases Animal Populations – monitor lizards, anyway.

“Science has lost its way, at a big cost to humanity“Researchers are rewarded for splashy findings, not for double-checking accuracy. So many scientists looking for cures to diseases have been building on ideas that aren’t even true.” – h/t outsideness! – see also: Trouble at the lab“Scientists like to think of science as self-correcting. To an alarming degree, it is not.”

These Unresolved Ethical Questions Are About to Get Real

bonus: Hunted by their own government – the fight to save Kalahari Bushmen“Survival International, which campaigns on behalf of tribal peoples, has called for tourists to boycott holidays in Botswana, which is forcing Kalahari Bushmen off their reserves.”

bonus bonus: How did ancient Greek music sound? – beautiful apparently! – h/t ed west!

bonus bonus bonus: Author: In China, ‘everyone is guilty of corruption’ – on guanxi.

bonus bonus bonus bonus: The couple having four babies by two surrogates“A British couple are to become parents of two sets of twin babies carried by two Indian surrogate women they have never met. Experts say twiblings – or children born to separate surrogates but created from the same batch of embryos – are not uncommon in India.”

bonus bonus bonus bonus bonus: Gang Rape in India, Routine and Invisible“[T]he Mumbai case provides an unusual glimpse into a group of bored young men who had committed the same crime often enough to develop a routine. The police say the men had committed at least five rapes in the same spot. Their casual confidence reinforces the notion that rape has been a largely invisible crime here, where convictions are infrequent and victims silently go away.” – see also: Trying to Make Sense of India’s Sexual Violence, State by State from t.greer.

bonus bonus bonus bonus bonus bonus: Insects aren’t gay, they’re just enthusiastic! Scientists discover same-sex mating in bugs is down to a rush to reproduce – h/t hbd bibliography!

bonus bonus bonus bonus bonus bonus bonus: Mysterious hum keeping people up all night ‘could be mating fish’“A council investigation was launched in Hythe, Southampton after some people had to move away because of the drone ‘pulsating’ through their homes.”

bonus bonus bonus bonus bonus bonus bonus bonus: Are conspiracy theories destroying democracy?“The more information we have about what governments and corporations are up to the less we seem to trust them. Will conspiracy theories eventually destroy democracy?” – h/t avi tuschman!

(note: comments do not require an email. monitor lizard!)

Flies see the world in slow motion, say scientists“Flies avoid being swatted in the same way Keanu Reeves dodges flying bullets in The Matrix, by watching time pass slowly, research suggests. The smaller an animal is, and the faster its metabolic rate, the slower time passes for it, scientists found. This means that across a wide range of species, time perception is directly related to size, with animals smaller than us seeing the world in slow motion…. ‘It’s tempting to think that for children time moves more slowly than it does for grown ups, and there is some evidence that it might…. People have shown in humans that flicker fusion frequency is related to a person’s subjective perception of time, and it changes with age. It’s certainly faster in children.’ – mind. blown.

Poverty Can Trump a Winning Hand of Genes“When psychologists first started studying twins, they found identical twins much more likely to have similar IQs than fraternal ones. They concluded that IQ was highly “heritable”—that is, due to genetic differences. But those were all high SES twins. Erik Turkheimer of the University of Virginia and his colleagues discovered that the picture was very different for poor, low-SES twins. For these children, there was very little difference between identical and fraternal twins: IQ was hardly heritable at all…. Richer children have similarly good educational opportunities, so genetic differences among them become more apparent…. But for poor children, haphazard differences in educational opportunity swamp genetic differences.”

Shy male birds keep closer ‘friends’“Shy male great tits have fewer ‘friends’ but build stronger bonds than bolder birds, researchers have found.” – speaking of birds: Warblers begin migrating after interbreeding.

Ancient genomes mirror mode of subsistence rather than geography in prehistoric Europe (preprint) – @dienekes’.

Pornography addiction leads to same brain activity as alcoholism or drug abuse, study shows“Cambridge University scientists reveal changes in brain for compulsive porn users which don’t occur in those with no such habit.”

Redneck Psychiatrists“Schizophrenia is more common in men than women – about 1.4 to 1. It’s more common in the lowest SES groups, although that may be downward drift. Schizophrenia is considerably more common among people of African ancestry…. Schizophrenia seems to be more common among people that grew up in cities – about twice as common.” – from greg cochran.

Stronger Sexual Impulses, Not Weaker Self-Control, May Explain Why Men Cheat More Than Women, Study Reveals

Painful and extreme rituals enhance social cohesion and charity“The study of 86 males in Mauritius found both observers and performers of the Kavadi were more charitable than those who only participated in the collective prayers. The researchers also found that higher levels of pain were positively associated with larger donations and a more inclusive self-identity.”

DNA Double Takechimeras! and other neat stuff.

Why parents think your partner isn’t good enough“[P]arents tend to give more resources to children whose partners provide less support, and that this leads to a conflict over mate choice…. ‘Parents are equally related to all of their children, whereas children value themselves more than their siblings — so each child wants to get more than their fair share of parental resources.’ This means that the children are willing to settle for a mate who is less caring than their parents would ideally like.”

The Social Life of Genes“Your DNA is not a blueprint. Day by day, week by week, your genes are in a conversation with your surroundings. Your neighbors, your family, your feelings of loneliness: They don’t just get under your skin, they get into the control rooms of your cells. Inside the new social science of genetics.” – h/t you know who you are!

Lifestyle Influences Metabolism via DNA Methylation“An unhealthy lifestyle leaves traces in the DNA. These may have specific effects on metabolism, causing organ damage or disease. Scientists of Helmholtz Zentrum München have now identified 28 DNA alterations associated with metabolic traits. This world-first epigenome-wide association study (EWAS) of modified genes and metabolites has been now published in the journal Human Molecular Genetics.”

From Slavs to slaves. Part II“With the Christianization of Eastern Europe, the trade in fair-skinned women and boys came to an end.” – from peter frost.

The Books Interview: David Epstein – author of The Sports Gene.

In Defense of Neanderthals – from jim goad.

UC Davis research finds Neandertals, not modern humans, made first specialized bone tools in Europe

Who Was Eating Salmon 45,000 Years Ago in the Caucasus?“Neandertals Probably Not as Rigid in Their Diet as Thought” – h/t hbd bibliography!

You’ll never be Chinese“Except where there is economic benefit to be had, communities do not act together, and when they do it is only to ensure equal financial compensation for the pollution, or the government-sponsored illegal land grab, or the poisoned children.”

The £29 DNA dating test that takes a swab of your saliva to find your perfect partner – they’re looking at hla genes. note that this is not an endorsement!

bonus: Sending food to Africa to solve famine is barmy, says Sir David Attenborough as he blames overcrowding for crisis

bonus bonus: The British babies made in India“The surrogate mothers of India’s Akanksha Clinic eagerly await their 600th delivery. But is there an ethical price to pay?” – is there a biological price to pay?

bonus bonus bonus: Sex Jihad raging in Syria, claims minister“A Tunisian minister has revealed local women are travelling to Syria to undertake ‘sex jihad’ by giving battlefield comfort to Islamist fighters battling the regime…. ‘After the sexual liaisons they have there in the name of “jihad al-nikah” – (sexual holy war, in Arabic) – they come home pregnant,’ Ben Jeddou told the MPs. “ – ooohhh-kay.

bonus bonus bonus bonus: joey prusak – good guy! (^_^)

bonus bonus bonus bonus bonus: Dinosaur feathers found in Alberta amber“Feathers believed to be from dinosaurs have been found beautifully preserved in Alberta amber. The primitive, hair-like feathers known as protofeathers likely belonged to theropods — dinosaurs similar to tiny Tyrannosaurus rexes — that roamed the swampy forests of Alberta 80 million years ago….”

bonus bonus bonus bonus bonus bonus: ‘Rotating moon’ filmed by Nasa – video

bonus bonus bonus bonus bonus bonus bonus: Is this the most extraordinary human brain ever seen? – yikes. =(

(note: comments do not require an email. great tits!)