Archives for posts with tag: innate differences between boys and girls

Ancient Ethiopian genome reveals extensive Eurasian admixture throughout the African continent“Here, we present a 12.5x coverage ancient genome of an Ethiopian male (‘Mota’) who lived approximately 4,500 years ago. We use this genome to demonstrate that the Eurasian backflow into Africa came from a population closely related to Early Neolithic farmers, who had colonized Europe 4,000 years earlier. The extent of this backflow was much greater than previously reported, reaching all the way to Central, West and Southern Africa, affecting even populations such as Yoruba and Mbuti, previously thought to be relatively unadmixed, who harbor 6-7% Eurasian ancestry.” – h/t john hawks! who tweeted: “First ancient DNA from Ethiopia shows that today’s sub-Saharan Africans are at least 0.2-0.7% Neanderthal ancestry!” – see also: First Ancient African Genome Reveals Vast Eurasian Migration“The man’s genome is, unsurprisingly, more closely related to present-day Ethiopian highlanders known as the Ari than to any other population the team examined, suggesting a clear line of descent for the Ari from ancient human populations living in the area. But further genetic studies show that the Ari also descend from people that lived outside Africa, which chimes with a previous study that discovered a ‘backflow’ of humans into Africa from Eurasia around 3,000 years ago.”

Eight thousand years of natural selection in Europe“The arrival of farming in Europe around 8,500 years ago necessitated adaptation to new environments, pathogens, diets, and social organizations…. We identify genome-wide significant signatures of selection at loci associated with diet, pigmentation and immunity, and two independent episodes of selection on height…. These results suggest that the modern South-North gradient in height across Europe is due to both increased steppe ancestry in northern populations, and selection for decreased height in Early Neolithic migrants to southern Europe. “

The Hybrid Origin of “Modern” Humans“Recent genomic research has shown that hybridization between substantially diverged lineages is the rule, not the exception, in human evolution. However, the importance of hybridization in shaping the genotype and phenotype of Homo sapiens remains debated. Here we argue that current evidence for hybridization in human evolution suggests not only that it was important, but that it was an essential creative force in the emergence of our variable, adaptable species.”

Neanderthal ‘flower children’ burials theory debunked“New research casts doubt on the idea that Neanderthals buried their dead covered in flowers.”

Intelligence in youth and health at age 50“Higher intelligence in youth is linked with better physical health at age 50.” – h/t andrew sabisky!

Chorionicity and Heritability Estimates from Twin Studies: The Prenatal Environment of Twins and Their Resemblance Across a Large Number of Traits“There are three types of monozygotic (MZ) twins. MZ twins can either share one chorion and one amnion, each twin can have its own amnion, or MZ twins can—like dizygotic twins—each have their own chorion and amnion. Sharing the same chorion may create a more similar/dissimilar prenatal environment and bias heritability estimates…. We conclude that the influence on the MZ twin correlation of the intra-uterine prenatal environment, as measured by sharing a chorion type, is small and limited to a few phenotypes.”

Genetic transmission of reading ability – h/t steve stewart williams! who tweeted: “If you want your kids to read, your best bet is to have kids with a reader.”

It All Began at Ararat, and Esau’s Revenge“Ancient DNA in Europe strongly indicates massive replacement [of hunter-gatherers by agriculturalists]. But, there is also suggestion of admixture with the local substrate. And, unlike the stylized model of Bellwood, it seems that there were multiple migrations after the initial pulse which reshaped the genetic and cultural landscape of human societies in the wake of agriculture.” – from razib.

Closing the Black-White IQ Gap Debate, Part I – from chanda chisala. and a response from peter frost: No, blacks aren’t all alike. Who said they were? – and previously on this blog: there’s more to human biodiversity than just racial differences.

The Association of Cognitive Ability with Right-wing Ideological Attitudes and Prejudice: A Meta-analytic Review“The present meta-analyses revealed an average effect size of r = −.20 [95% confidence interval (95% CI) [−0.23, −0.17]; based on 67 studies, N = 84 017] for the relationship between cognitive ability and right-wing ideological attitudes and an average effect size of r = −.19 (95% CI [−0.23, −0.16]; based on 23 studies, N = 27 011) for the relationship between cognitive ability and prejudice.”

[male] Chimps like boys toys too“If you want to know why young boys play with toy guns, you could do worse than consider why young male chimpanzees play with leaves and stones.” – h/t darren burke! who tweeted: “Western social constructivism is so insidious and widespread it is even affecting wild chimpanzees now!” – (~_^)

Ravens cooperate, but not with just anyone“Ravens detect cheaters in cooperation.”

Understanding the Cognitive and Genetic Underpinnings of Procrastination: Evidence for Shared Genetic Influences With Goal Management and Executive Function Abilities – procrastination (at least) 28% heritable. will have to read original paper. tomorrow, maybe. (~_^)

Personality Traits Increasingly Important for Male Fertility: Evidence from Norway“[P]ersonality relates to men’s and women’s fertility differently; conscientiousness decreases female fertility, openness decreases male fertility and extraversion raises the fertility of both sexes. Neuroticism depresses fertility for men, but only for those born after 1956.”

Host genetic variation impacts microbiome composition across human body sites“Our results highlight the role of host genetic variation in shaping the composition of the human microbiome, and provide a starting point toward understanding the complex interaction between human genetics and the microbiome in the context of human evolution and disease.”

DNA At the Fringes: Twins, Chimerism, and Synthetic DNA – h/t genetics and society! who tweeted: “Chimeras could undermine DNA forensics & use of DNAtesting as conclusive proof of crime & family.”

Ethnic differences in the association between depression and chronic pain: cross sectional results from UK Biobank [pdf] – h/t don lyall!

Emotion, rationality, and decision-making: how to link affective and social neuroscience with social theory

Women and men react differently to infidelity“While men are most jealous of sexual infidelity, women are most jealous of emotional infidelity.” – w.e.i.r.d. study. (n=1000).

‘Safe spaces’ exist because universities treat secular ideas as sacred“The most influential effect of this cultural and political imbalance is that academia has ignored the increasing evidence that human traits are heavily influenced by hereditary factors, most prominently in intelligence and sexual differences. This has a huge bearing on public policy, especially when so much of policy is involved in tackling inequality of various kinds. It would be like trying to reduce economic inequality while pretending that wealth cannot be inherited, because that’s offensive to people’s parents, and that all fortunes were the results of education, hard work or sheer luck.” – from ed west.

Relics of the Blank Slate, as Excavated at “Ethics” Magazine“There’s a reason that the Blank Slaters clung so bitterly to their absurd orthodoxy for so many years. If there is such a thing as human nature, then all the grandiose utopias they concocted for us over the years, from Communism on down, would vanish like so many mirages.” – from helian.

Anthropologist: “I’ve Never Been So Disgusted with My Own Data” – from steve sailer.

“Ethics” is advertising – david chapman on virtue signaling (trans: signalling. (~_^) ).

Two Fed economists tried to replicate some top economic studies — and the results are dreadful – from mike bird.

The shifting tide of American immigration – from colin woodard.

Missing piece of Gilgamesh Epic discovered

Pompeii Victims’ Bodies Revealed in [ct] Scans: Photos

Excavations at Mexican ruin site yields new details of Aztecs’ sacrifice of captured Spaniards“It was one of the worst defeats in one of history’s most dramatic conquests: Only a year after Hernan Cortes landed in Mexico, hundreds of people in a Spanish-led convey were captured, sacrificed and apparently eaten.”

bonus: Most worker ants are slackers“[N]ew research shows that many ants in a colony seem to specialize in doing nothing at all. To get a closer look at how these ants filled their time, researchers marked every member of five lab-based colonies with dots of colored paint. Over the course of 2 weeks, a high-definition camera recorded 5-minute segments of the ants in action six times a day, capturing their behavior (or lack thereof). Out of the ‘workers,’ 71.9% were inactive at least half the time, and 25.1% were never seen working. A small fraction of the ants, just 2.6%, were always active during observation, the researchers wrote last month in Behavioral Ecology and Sociobiology.”

bonus bonus: How to Dupe a Dung Beetle“A case of biological mimicry has been spotted in Ceratocaryum argenteum, a South African plant that tricks dung beetles into spreading its stinky seeds.”

bonus bonus bonus: Elephants: Large, Long-Living and Less Prone to Cancer“Dr. Schiffman and his colleagues found that elephants have evolved new copies of the p53 gene [“a gene that is crucial for preventing cancer”]. While humans have only one pair of p53 genes, the scientists identified 20 pairs in elephants.”

bonus bonus bonus bonus: DNA Sequenced for New Zealand’s First Dog – the kurī. woof!

bonus bonus bonus bonus bonus: Watch Drones Drop Thousands of Moths on Crops

bonus bonus bonus bonus bonus bonus: Honour, community and hierarchy in the feasts of the archery and crossbow guilds of Bruges, 1445–81

and the tweet of the week… (~_^)

(note: comments do not require an email. “Humans come then go, that is the way fate decreed on the Tablets of Destiny.”)

‘Tree of life’ for 2.3 million species released“A first draft of the ‘tree of life’ for the roughly 2.3 million named species of animals, plants, fungi and microbes — from platypuses to puffballs — has been released. A collaborative effort among eleven institutions, the tree depicts the relationships among living things as they diverged from one another over time, tracing back to the beginning of life on Earth more than 3.5 billion years ago. Tens of thousands of smaller trees have been published over the years for select branches of the tree of life — some containing upwards of 100,000 species — but this is the first time those results have been combined into a single tree that encompasses all of life.”

Taste Mutation Helps Monkeys Enjoy Human Food – nice example of recent and local evolution.

SNP hits on cognitive ability from 300k individuals – from steve hsu.

General Cognitive Ability Is Almost Perfectly Stable from Early Adulthood to Late Middle Age“[I]ndividual differences in general intelligence that exist at age 18 are almost perfectly preserved to age 60, after which this stability starts to slowly break down.” – @ human varieties.

Genome-wide autozygosity is associated with lower general cognitive ability“We found that increased levels of autozygosity predicted lower general cognitive ability, and estimate a drop of 0.6 s.d. among the offspring of first cousins (P=0.003–0.02 depending on the model). This effect came predominantly from long and rare autozygous tracts, which theory predicts as more likely to be deleterious than short and common tracts.” – discuss. (~_^)

Study Reports Rare Genetic Mutations Responsible for Almost Half of Autism Cases“Quantitative study identifies 239 genes whose ‘vulnerability’ to devastating de novo mutation makes them priority research targets.”

Genetic transmission of reading ability – h/t to the siberian fox! who tweeted: “Heritability of reading ability is 62%. Previous estimates lower because of assortive mating (r=.38).”

Clannishness – the Series: Zigzag Lightning in the Brain – from jayman. see also: a few thoughts. from me! (^_^)

Inequality among 32 London Boroughs: An S factor analysis and The general religious factor among Muslims: a multi-level factor analysis – from emil kirkegaard.

It’s official: The Maltese are the fattest in all of the European Union“Despite Malta’s weighty problem, the Maltese have a less than average prevalence of premature mortality from cardiovascular diseases, cancer, diabetes and chronic respiratory disease.” – h/t staffan!

Support for linguistic macrofamilies from weighted sequence alignment“This article reports findings regarding the automatic classification of Eurasian languages using techniques from computational biology (such as sequence alignment, phylogenetic inference, and bootstrapping). Main results are that there is solid support for the hypothetical linguistic macrofamilies Eurasiatic and Austro-Tai.”

Our Mental Noise Grows More Intense As We Age, So Our Brains Lose Processing Speed Over Time

Ancient hominid ears were tuned to high frequencies“A. africanus and P. robustus could have heard high-frequency consonants associated with the letters t, k, f and s better than either chimps or present-day people do, the team found.”

Extreme Altruism – The Case of the Pathological Do-Gooder – from helian.

Personal values and intergroup outcomes of concern for group honor – h/t andrew sabisky! who tweeted: “group honour culture = more empathy, lower openness, more endorsement of violence towards Americans.”

Scope Insensitivity in Helping Decisions: Is It a Matter of Culture and Values? – h/t robin hanson! who tweeted: “Contrast to westerners, collectivist Bedouin NOT more willing to help one concrete victim than a group of victims.”

Indigenous Belief in a Just World: New Zealand Māori and other Ethnicities Compared“Māori have more ‘leftist’ beliefs than non-Māori (i.e., nearly 60% of Māori blame an unfair society compared to 41% of non-Māori).”

Tiny mitochondria play outsized role in human evolution and disease

An architecture for encoding sentence meaning in left mid-superior temporal cortex – h/t steve pinker! who tweeted: “The most important paper in cognitive neuroscience in many years: How does the brain represent who did what to whom?”

Sex differences and stress across the lifespan – h/t kevin mitchell!

Does the Welfare State Destroy the Family? Evidence from OECD Member Countries“[A]n expansion in the welfare state increases the fertility, marriage, and divorce rates with a quantitatively stronger effect on the marriage rate. We conclude that the welfare state supports family formation in the aggregate. Further, we find that the welfare state decouples marriage and fertility, and therefore, alters the organization of the average family.”

What is a standard deviation? A definition. – from pumpkin person.

Data analysis yields striking maps of human expansion in North American Holocene“[A] group of paleoclimatologists and anthropologists analyzed data recorded in the Canadian Archaeological Radiocarbon Database (CARD), which aggregates 35,905 radiocarbon samples from archaeological sites across the North American continent, and was created by Dr. Richard Morlan of the Canadian Museum of History. By applying a kernel density estimation method to the data, the researchers produced the first maps of temporally distinct paleo-demographic trends that correspond well to existing evidence of human expansion across North America in the Holocene.”

Scientists Discover 9,000-Year-Old Case of Decapitation in the Americas

Remains of 6,000-year-old first settlers [in ireland] found

Archaeological breakthrough could solve the mystery of Greenland’s Vikings

Regional microbial signatures positively correlate with differential wine phenotypes: evidence for a microbial aspect to terroir

bonus: Growing a penis at 12: the ‘Guevedoce’ boys of the Dominican Republic – (O.O) – h/t @don_arete!

and the tweet of the week! (~_^) :

(note: comments do not require an email. 5-alpha-reductase deficiency.)

What Your DNA Says About Medieval History“A new study uses genetic data from living people to trace millennia-old migration patterns…. [M]uch of what Capelli and his colleagues discovered meshed with what historians already knew. For example, among northern Europeans, highest rate of admixing took place ‘around the late first millennium C.E., a time known to have involved significant upheaval in Europe,’ while admixture between north African and southern European populations was dated to a time span ‘consistent with migrations associated with the Arabic Conquest of the Iberian peninsula.’ But there were surprises, too. Most notably, Capelli and his colleagues discovered evidence for an influx of Mongolians into Europe that predated the reign of Ghengis Khan.” – orig. research article: The Role of Recent Admixture in Forming the Contemporary West Eurasian Genomic Landscape.

Inuit Study Adds Twist to Omega-3 Fatty Acids’ Health Story“A study published on Thursday in the journal Science reported that the ancestors of the Inuit evolved unique genetic adaptations for metabolizing omega-3s and other fatty acids. Those gene variants had drastic effects on Inuit’s bodies, reducing their heights and weights. Rasmus Nielsen, a geneticist at the University of California, Berkeley, and an author of the new study, said that the discovery raised questions about whether omega-3 fats really were protective for everyone, despite decades of health advice. ‘The same diet may have different effects on different people,’ he said…. The researchers found several genetic variants at different locations in the genome that were unusually common in the Inuit, compared with people in Europe or China. Several of these variations occurred within a cluster of genes that direct construction of enzymes called fatty acid desaturases. (The genes are called FADS, for short….) Even more intriguing was the fact that one of these gene variants was present in almost every Inuit in the study. It is much less common in other populations: About a quarter of Chinese people have it, compared with just 2 percent of Europeans. Natural selection is the only known way this gene variant could have become so common in the Inuit. Dr. Nielsen said this adaptation might have arisen as long ago as 20,000 years, when the ancestors of the Inuit were living in the Beringia region, which straddles Alaska and Siberia…. The adaptation did more than just change blood levels of fatty acids, the scientists found. Inuit who carried two copies of the variant gene were on average an inch shorter and 10 pounds lighter than those without a copy.” – orig. research article: Greenlandic Inuit show genetic signatures of diet and climate adaptation. see also Your Genes Are What You Eat from razib.

Height-reducing variants and selection for short stature in Sardinia“[K]nown height-decreasing alleles are at systematically higher frequencies in Sardinians than would be expected by genetic drift. The findings are consistent with selection for shorter stature in Sardinia and a suggestive human example of the proposed ‘island effect’ reducing the size of large mammals.” – h/t andrew sabisky!

Are humans still evolving? Yes, both globally and locally. – from jerry coyne.

5 key facts about the nuclear DNA from Sima de los Huesos“If confirmed, the results will push back the H. sapiens-H. neanderthalensis ancestor beyond 400 KYA. Meyer suggested that the ancestors of H. sapiens could have diverged from the branch leading to neandertals and denisovans 550 K to 765 K years ago. It may be possible that H. sapiens evolved in western Eurasia and later migrated back into Africa. The fossils from Europe, Asia and Africa in the 400 Ka. period are physically very diverse and may represent multiple species, only one of which could be the ancestor of today’s humans. For example, Chris Stringer thinks it may be needed to look at Homo antecessor and not Homo heidelbergensis as our last common ancestor with neandertals.”

New DNA tests on ancient Denisovan people ‘shows them occupying Altai cave 170,000 years ago’“Prehistoric Siberians lived in Denisova Cave earlier than scientists realised – new claim based on state-of-the-art technology.” – h/t paleoanthropology!

Origins, admixture and founder lineages in European Roma“We found a set of founder lineages, present in the Roma and virtually absent in the non-Roma, for the maternal (H7, J1b3, J1c1, M18, M35b, M5a1, U3, and X2d) and paternal (I-P259, J-M92, and J-M67) genomes. This lineage classification allows us to identify extensive gene flow from non-Roma to Roma groups, whereas the opposite pattern, although not negligible, is substantially lower (up to 6.3%). Finally, the exact haplotype matching analysis of both uniparental lineages consistently points to a Northwestern origin of the proto-Roma population within the Indian subcontinent.”

Why I’m sceptical about the idea of genetically inherited trauma“A recent scientific paper claiming that the children of Holocaust survivors showed evidence of inherited stress was deeply flawed – here’s why.”

Population genetic differentiation of height and body mass index across Europe“Here we find that many independent loci contribute to population genetic differences in height and body mass index (BMI) in 9,416 individuals across 14 European countries.”

North-South divide, Japanese style – from dr. james thompson.

Genetics of IQ and lifespan and Genius? Avoid rare functional genes and Heritability of Specific Cognitive Abilities and Schizophrenia and cognitive decline and g for Latinos and White matter efficiency predicts women’s IQ, but not men’s – all also from dr. james thompson!

SNP hits on cognitive ability from 300k individuals – from steve hsu. h/t holtz!

Do smart girls postpone first sex? and Do women find bright men sexy? – and even MORE from dr. james thompson!! whew!

Green Arabia’s key role in human evolution“Scientists have been illuminating the vital role played by the Arabian Peninsula in humankind’s exodus from Africa. Far from being a desert, the region was once covered by lush vegetation and criss-crossed by rivers, providing rich hunting grounds for our ancestors.”

The UK10K project identifies rare variants in health and disease – h/t kevin mitchell!

Genetics of aggressive behavior: An overview – h/t brian boutwell!

Sons of the Soil, Migrants, and Civil War“In nearly a third of ethnic civil wars since 1945, the conflict develops between members of a regional ethnic group that considers itself to be the indigenous “sons of the soil” and recent migrants from other parts of the country.” – h/t whyvert!

It’s finally out: The big review paper on the lack of political diversity in social psychology“Psychologists have demonstrated the value of diversity – particularly diversity of viewpoints – for enhancing creativity, discovery, and problem solving. But one key type of viewpoint diversity is lacking in academic psychology in general and social psychology in particular: political diversity.” – from jonathan haidt.

The genetics of alcohol dependence: Twin and SNP-based heritability, and genome-wide association study based on AUDIT scores – h/t amir sariaslan!

Chronotype Associations with Depression and Anxiety Disorders in a Large Cohort Study – h/t emily deans! who tweeted: “‘Morning people’ less likely to be depressed in this large and relatively thorough observational study.” – (morning people depress me. (~_^) )

The Hormone That Bonds Humans to Dogs – h/t old whig! who tweeted: “Evolutionary change is faster than we think? Case study: oxytocin.”

Does the Gender of Offspring Affect Parental Political Orientation? – h/t ben southwood! who tweeted: “Studies on offspring gender & political orientation plagued by publication bias; actually there’s no relationship.”

Do Angry Birds Make for Angry Children? A Meta-Analysis of Video Game Influences on Children’s and Adolescents’ Aggression, Mental Health, Prosocial Behavior, and Academic Performance“Overall, results from 101 studies suggest that video game influences on increased aggression (r = .06), reduced prosocial behavior (r = .04), reduced academic performance (r = −.01), depressive symptoms (r = .04), and attention deficit symptoms (r = .03) are minimal.” – h/t joseph schwartz!

Ancient campfires show early population numbers [in australia]“ANU archaeologist Alan Williams used radio carbon dating technology to examine charcoal dates from more than 1000 prehistoric campfires and based on this he says populations appear to have increased steadily until 25,000 years ago…. After this initial increase, he says, population levels remained steady or even declined from 25,000 years ago, during the more arid Last Glacial Maximum (25,000 to 13,000 years ago) when temperatures were about ten degrees cooler…. Campfire numbers began to grow again 13,000 years ago when the northern wet season re-emerged.”

Aboriginal ‘memories’ of Australia’s coastline go back more than 7,000 years

History became legend, legend became myth: Crater Lake – h/t razib! who tweeted: “8,000 year old explosion preserved in folk memory of klamath indians?”

Ancient Script Spurs Rethinking of Historic ‘Backwater’“At a temple site in the Republic of Georgia, letters carved in stone could change the way we see the development of writing.”

bonus: Microbiologists Keep Finding Giant Viruses in Melting Permafrost

bonus bonus: Ancient Cats Drove Ancient Dogs to Extinction – woof? (O.O)

bonus bonus bonus: this year’s ig nobel mathematics prize went to the authors of The Case of Moulay Ismael – Fact or Fancy?“Textbooks on evolutionary psychology and biology cite the case of the Sharifian Emperor of Morocco, Moulay Ismael the Bloodthirsty (1672–1727) who was supposed to have sired 888 children. This example for male reproduction has been challenged and led to a still unresolved discussion. The scientific debate is shaped by assumptions about reproductive constraints which cannot be tested directly — and the figures used are sometimes arbitrary. Therefore we developed a computer simulation which tests how many copulations per day were necessary to reach the reported reproductive outcome…. The results indicate that Moulay Ismael could have achieved this high reproductive success. A comparison of the three conception models highlights the necessity to consider female sexual habits when assessing fertility across the cycle. We also show that the harem size needed is far smaller than the reported numbers.” (~_^)

and the tweet of the week!:


(note: comments do not require an email. moulay ismael the bloodthirsty!)

a linkfest! (^_^) ’cause i hate linkfasts, too. (*^_^*)

Whole genome sequence analyses of Western Central African Pygmy hunter-gatherers reveal a complex demographic history and identify candidate genes under positive natural selection“African Pygmies practicing a mobile hunter-gatherer lifestyle are phenotypically and genetically diverged from other anatomically modern humans, and they likely experienced strong selective pressures due to their unique lifestyle in the Central African rainforest…. Our two best-fit models both suggest ancient divergence between the ancestors of the farmers and Pygmies, 90,000 or 150,000 years ago. We also find that bi-directional asymmetric gene-flow is statistically better supported than a single pulse of unidirectional gene flow from farmers to Pygmies, as previously suggested…. We found that genes and gene sets involved in muscle development, bone synthesis, immunity, reproduction, cell signaling and development, and energy metabolism are likely to be targets of positive natural selection in Western African Pygmies or their recent ancestors.”

Directional dominance on stature and cognition in diverse human populations“[I]ncreased homozygosity was associated with decreased trait value, equivalent to the offspring of first cousins being 1.2 cm shorter and having 10 months’ less education. Similar effect sizes were found across four continental groups and populations with different degrees of genome-wide homozygosity, providing evidence that homozygosity, rather than confounding, directly contributes to phenotypic variance. Contrary to earlier reports in substantially smaller samples5, 6, no evidence was seen of an influence of genome-wide homozygosity on blood pressure and low density lipoprotein cholesterol, or ten other cardio-metabolic traits. Since directional dominance is predicted for traits under directional evolutionary selection7, this study provides evidence that increased stature and cognitive function have been positively selected in human evolution, whereas many important risk factors for late-onset complex diseases may not have been.” – see also Not tonight, cousin from dr. james thompson. and see also Inbreeding from greg cochran. and see also Directional dominance on stature and cognition from steve hsu.

Genes Unite Executive Functions in Childhood [pdf] – h/t brian boutwell! who tweeted: “Shared genes explain all of the covariance in exec functioning items. No parenting effects to be found.”

200 Blog Posts – Everything You Need to Know (To Start) and The Rise of Universalism and Demography is Destiny, American Nations Edition and National Prosperity – jayman’s been on a roll lately! (^_^) each of these warrants your close attention!

Heritability and the evolution of cognitive traits

CNVs in neuropsychiatric disorders“Over the last few years at least 11 copy number variations (CNVs) have been shown convincingly to increase risk to developing schizophrenia: deletions at 1q21.1, NRXN1, 3q29, 15q11.2, 15q13.3 and 22q11.2, and duplications at 1q21.1, 7q11.23, 15q11.2-q13.1, 16p13.1 and proximal 16p11.2. They are very rare, found cumulatively in 2.4% of patients with schizophrenia and in only 0.5% of controls. They all increase risk for other neurodevelopmental disorders, such as developmental delay and autism spectrum disorders, where they are found at higher rates (3.3%). Their involvement in bipolar affective disorder is much less prominent. All of them affect multiple genes (apart from NRXN1) and cause substantial increases in risk to develop schizophrenia (odds ratios of 2 to over 50). Their penetrance for any neurodevelopmental disorder is high, from ∼10% to nearly 100%. Carriers of these CNVs display cognitive deficits, even when free of neuropsychiatric disorders.”

Improving Phenotypic Prediction by Combining Genetic and Epigenetic Associations [pdf] – h/t dr. xaverius!

County level homicide rates by race/ethnicity of victim and On the effects of wealth on the B-W gaps, a response to questions posed by a commenter @random critical analysis.

the much discussed post The IQ Gap Is No Longer a Black and White Issue – from chanda chisala. see also Chanda Chisala: An African Hereditarian?“If evolution applies to all of us, that includes Africans. It is perfectly possible that some African sub-groups are brighter than others. Any geographic group which takes care to encourage bright persons to marry one another could see positive effects after 20-30 generations of consistently strong selection, if those brighter parents have more surviving offspring, which is likely.” – from dr. james thompson. and see also The Jews of West Africa? from peter frost. and see also my post: there’s more to human biodiversity than just racial differences.

The Water-Crossers – from greg cochran.

Ancestry Matters: Patrilineage Growth and Extinction – h/t ben southwood! who tweeted: “Higher status Chinese patrilineages in the 18th and 19th centuries had more ancestors for hundreds of years after.”

The puzzle of European hair, eye, and skin color – from peter frost.

The people who need very little sleep

How evolutionary psychology may explain the difference between male and female serial killers“[R]esearch has shown that male serial killers tend to stalk and kill strangers. But FSKs tend to kill people they know. It seems, then, that MSKs are hunters and FSKs are gatherers.”

Is the Romantic–Sexual Kiss a Near Human Universal – apparently not! – “The romantic–sexual kiss was present in a minority of cultures sampled (46%). Moreover, there is a strong correlation between the frequency of the romantic–sexual kiss and a society’s relative social complexity: the more socially complex the culture, the higher frequency of romantic–sexual kissing.”

Men are both dumber and smarter than women – just an ok article, but interesting to see this out there *at all*.

Historical Artifacts of the Blank Slate – from helian.

On a Fast Track – Can rapid genome sequencing at birth help save lives?

Genomics Industry Generating Huge Amounts Of Data Due To DNA Sequencing – yay!

Ageing rates vary widely, says study“A study of people born within a year of each other has uncovered a huge gulf in the speed at which their bodies age…. [S]ome people had almost stopped ageing during the period of the study, while others were gaining nearly three years of biological age for every twelve months that passed.” – original research article: Quantification of biological aging in young adults.

Reacting to Spree Killings, Progressively – @thosewhocansee.

for you brits: Is that stranger opposite you a distant cousin?

bonus: Pluto’s discoverer’s ashes will be the first human remains to leave the solar system — glued to the side of a space probe – *sniff*

bonus bonus: r.i.p. conrad – *sniff*

bonus bonus bonus: tweet of the week! (~_^) >>

(note: comments do not require an email. r.i.p. conrad. *sniff*)

a linkfest! =D

Experimental evolution reveals hidden diversity in evolutionary pathways“Our findings show that parallel genetic evolution is strongly biased by constraints and we reveal the genetic bases. From such knowledge, and in instances where new phenotypes arise via gene activation, we suggest a set of principles: evolution proceeds firstly via pathways subject to negative regulation, then via promoter mutations and gene fusions, and finally via activation by intragenic gain-of-function mutations. These principles inform evolutionary forecasting and have relevance to interpreting the diverse array of mutations associated with clinically identical instances of disease in humans.”

Selectionism Strikes Back! – from razib.

Genomes carry a heavy burden“Most people’s DNA contains genetic mutations that are potentially lethal to offspring…. Most people carry one or two genetic mutations that can cause early death or infertility in their offspring….”

World’s oldest stone tools discovered in Kenya“Researchers…say they have found the oldest tools made by human ancestors — stone flakes dated to 3.3 million years ago. That’s 700,000 years older than the oldest-known tools to date, suggesting that our ancestors were crafting tools several hundred thousand years before our genus Homo arrived on the scene. If correct, the new evidence could confirm disputed claims for very early tool use, and it suggests that ancient australopithecines like the famed ‘Lucy’ may have fashioned stone tools, too.”

Neanderthals manipulated the bodies of adults and children shortly after death

Neandertal flutes debunked – @dienekes’.

IQ prediction from structural MRI – from steve hsu. see also: MRI-Based Intelligence Quotient (IQ) Estimation with Sparse Learning.

New brain science shows poor kids have smaller brains than affluent kids – see also: Credit, where credit is due, to Lyndsey Layton and Income, brain, race: Prof Kimberly Noble replies and Howitzer or Katyusha: Reply to Prof Noble at dr. james thompson’s blog. – and see also: In today’s social science, wishing makes it so – from charles murray.

Gene study may explain why some remain quick thinkers“Genetic differences could explain why some people are quicker thinkers in middle age and later life, a study of data from 30,000 people suggests.” – see also: GWAS for executive function and processing speed suggests involvement of the CADM2 gene.

Prediction of brain age suggests accelerated atrophy after traumatic brain injury – h/t stuart ritchie! who tweeted: “Super-cool new paper on how to predict someone’s age just from a brain image (r = .92!)”

National Wealth and IQ at the Edge: American Exceptionalism, East Asian Mediocrity – anatoly karlin’s “big-ass blog on national wealth, IQ, HBD, East Asians, smart fractions, etc.” (~_^)

In the beginning was the Word – dr. james thompson blogs on the recent woodley et al. paper “By their words ye shall know them: Evidence of genetic selection against general intelligence and concurrent environmental enrichment in vocabulary usage since the mid 19th century.”

Born That Way – from greg cochran.

Female Same-Sex Attraction Revisited – from jayman.

Examining the S factor in Mexican states – from emil kirkegaard.

Sex differences and vulnerability: how the male-female divide affects health“[S]ome studies have shown that premature baby girls will grow up to suffer greater language deficits than premature boys, whereas boys exposed to certain prenatal toxins will suffer greater deficits to spatial skills than girls similarly exposed, but because sex differences were never the original focus of the research no one, until Geary, has united these sex specific developmental problems and placed them in evolution’s bigger picture. Geary explains, ‘Sexually selected traits are the first to go; for example, low level exposure to prenatal toxins will affect play in boys but not their IQ: if you don’t measure the right thing you will fail to detect underlying problems.'” – h/t steve stewart williams!

Men up to five times more likely to commit sex crimes than the average male if they have brother or father convicted of a sex offence – h/t claire lehmann! who tweeted: “Survey of 21,566 men convicted of sex crimes from 1973- 2009 has revealed a strong genetic component to sex offending.” – see also: Sexual offending runs in families: A 37-year nationwide study.

Aggressive-Antisocial Boys Develop Into Physically Strong Young Men“We found that males’ antisocial tendencies temporally precede their physical formidability. Boys, but not girls, with greater antisocial tendencies in childhood attained larger increases in physical strength between the ages of 11 and 17. These results support sexual selection theory, indicating an adaptive congruence between male-typical behavioral dispositions and subsequent physical masculinization during puberty.”

Childhood Self-Control and Unemployment Throughout the Life Span: Evidence From Two British Cohort Studies“Analyzing unemployment data from two nationally representative British cohorts (N = 16,780), we found that low self-control in childhood was associated with the emergence and persistence of unemployment across four decades. On average, a 1-SD increase in self-control was associated with a reduction in the probability of unemployment of 1.4 percentage points after adjustment for intelligence, social class, and gender.”

Enlisting in the Military: The Influential Role of Genetic Factors“Given that enlistment in the U.S. military is completely voluntary, there has been a great deal of interest in identifying the various factors that might explain why some people join the military, whereas others do not. The current study expanded on this line of literature by estimating the extent to which genetic and environmental factors explained variance in the liability for lifetime participation in the military. Analysis of twin pairs drawn from the National Longitudinal Study of Adolescent to Adult Health (Add Health) revealed that 82% of the variance was the result of genetic factors, 18% of the variance was the result of nonshared environmental factors, and none of the variance was accounted for by shared environmental factors.” – from brian boutwell et al.

Risk of Suicide Among US Military Service Members Following Operation Enduring Freedom or Operation Iraqi Freedom Deployment and Separation From the US Military“Findings do not support an association between deployment and suicide mortality in this cohort. Early military separation (<4 years) and discharge that is not honorable were suicide risk factors.” – h/t michael story!

Verbal ability as a predictor of political preferences in the United States, 1974–2012“[H]igher vocabulary scores are associated with a greater likelihood that people place themselves on the ideological and political spectrum and that they vote in presidential elections, but have only small relationships with liberal-versus-conservative self-identification.”

Do our genes tell us how to vote? Study of twins says they might

On the Malleability and Plasticity of the History of the Blank Slate and 21st Century Moral Philosophy Advances Boldly into the 19th Century – from helian.

More on the younger Franz Boas – from peter frost.

Surnames and Y-Chromosomal Markers Reveal Low Relationships in Southern Spain – ruh roh.

New study finds genetic predisposition for noise-induced hearing loss

New function of obesity gene revealed

The placebome: Where genetics and the placebo effect meet

Chimps That Hunt Offer a New View on Evolution“[A] 10-year study of chimpanzees in Senegal shows females playing an unexpectedly big role in hunting and males, surprisingly, letting smaller and weaker hunters keep their prey. The results do not overturn the idea of dominant male hunters, said Jill D. Pruetz of Iowa State University, who led the study. But they may offer a new frame of reference on hunting, tools and human evolution. ‘We need to broaden our perspective,’ she said.”

Upper Palaeolithic ritualistic cannibalism at Gough’s Cave (Somerset, UK): The human remains from head to toe“Our present analysis of the postcrania has identified a far greater degree of human modification than recorded in earlier studies. We identify extensive evidence for defleshing, disarticulation, chewing, crushing of spongy bone, and the cracking of bones to extract marrow. The presence of human tooth marks on many of the postcranial bones provides incontrovertible evidence for cannibalism.”

Yes, You Can Catch Insanity“A controversial disease revives the debate about the immune system and mental illness.” – pediatric autoimmune neuropsychiatric disorders or “PANDAS”.

Hatfield and McCoy Feud — The Real Thing

Colors help set body’s internal clock“[Mice] use light’s changing color to set their own clocks, a finding that researchers expect will hold for humans, too.”

The Myth of the Angry Atheist“[T]hese results support the idea that people believe atheists are angry individuals, but they do not appear to be angrier than other individuals in reality.”

Flowers Are “Darker” at Lower Latitudes“UV radiation may explain why plants and animals closer to the equator come in darker varieties.”

The Disease That Turned Us Into Genetic-Information Junkies – brief history on tay–sachs disease research.

Antibiotic Resistant Bacteria Could Predate Antibiotics“A South American tribe, called the Yanomami, which was isolated for about 11,000 years prior to 2009, have gut bacteria that carry antibiotic resistance genes, according to new research. The Yanomami’s microbiome is far more diverse than that of Europeans or North Americans, but it also contains antibiotic resistant genes, despite never having had antibiotics. The findings suggest antibiotic resistance predates antibiotics, although it is possible the Yanomami ingested naturally occurring antibiotics in soil at some point.” – see also: The microbiome of uncontacted Amerindians.

Rotherham Worker ‘Told To Give Girls To Abusers’“The ex-protection worker says she repeatedly raised concerns about men taking girls away but her boss told her to ‘let them go’.” – also: State wards being groomed for prostitution by paedophile gangs“Organised gangs of paedophiles are grooming state wards as young as 12 for prostitution. Veteran child protection workers have told the Herald Sun they are powerless to protect the children in their care and that the sexual exploitation of state wards is ‘endemic’…. Victoria Police has set up a taskforce to investigate a gang of Afghani men in Dandenong suspected of preying on teens in care.” – australia now. =/

bonus: Jurassic Park in real life: The race to modify the DNA of endangered animals and resurrect extinct ones“Professor Church has applied a sophisticated and revolutionary ‘gene editing’ technique known as Crispr and has managed to get it working in elephant cells to carry out 14 precise changes to its genome. ‘We are now working on in vitro organogenesis [organ formation] and embryogenesis [embryo formation],’ he told The Independent in an email.”

bonus bonus: Genome Digest – findings from genomes of mountain gorilla, pseudomonas aeruginosa, canary, bird flu strain, and leprosy bacterium.

bonus bonus bonus: Through This Chemical Loop, Dogs Win Our Hearts

(note: comments do not require an email. woof?)

Human evolution tied to a small fraction of the genome“Only about 7.5 percent of the human genetic instruction book shaped the evolution of human traits, a new study suggests. And it’s often not genes, but the how-to instructions for using those genes that are most important, researchers report January 19 in Nature Genetics…. Previously, researchers have mostly looked for evolutionary clues in protein-producing genes because proteins do much of the important work in cells and organisms. Altering a protein may change the way an organism looks or acts. But mutations that alter proteins often are devastating to an organism and therefore aren’t passed on to offspring. Gulko and colleagues found that only 9 percent of the DNA that got evolution’s attention resides in protein-coding parts of the genome that are shared with other species. About 52 percent of the places showing signs of natural selection were in intergenic regions, the stretches of DNA between genes. Another 35 percent were in introns — spacer DNA found within genes but not involved in encoding proteins. Both intergenic regions and introns often contain DNA responsible for controlling gene activity. These findings suggest that human evolution works mostly through changes in how genes are used, rather than by altering genes and the proteins they encode.”

The Wrists of Birds Reveal Evolution Undoing Itself“Contrary to earlier claims, a new study shows that evolution may be reversible.” – previously from greg cochran: Back to the trees.

Kennewick Man was Native American“‘Genetic analysis is still under way in Denmark, but documents obtained through the federal Freedom of Information Act say preliminary results point to a Native-American heritage.'” – from dienekes. see also from razib: Native Americans Are Evolutionarily Elegant“One insight of modern ancient DNA is that there has been a great deal of population turnover over the past ~10,000 years, as well as admixture between disparate lineages. When Kennewick Man died ~9,000 years ago Europeans as we understand them did not exist genetically.”

The Genetic Ancestry of African Americans, Latinos, and European Americans across the United States“Over the past 500 years, North America has been the site of ongoing mixing of Native Americans, European settlers, and Africans (brought largely by the trans-Atlantic slave trade), shaping the early history of what became the United States. We studied the genetic ancestry of 5,269 self-described African Americans, 8,663 Latinos, and 148,789 European Americans who are 23andMe customers and show that the legacy of these historical interactions is visible in the genetic ancestry of present-day Americans. We document pervasive mixed ancestry and asymmetrical male and female ancestry contributions in all groups studied. We show that regional ancestry differences reflect historical events, such as early Spanish colonization, waves of immigration from many regions of Europe, and forced relocation of Native Americans within the US. This study sheds light on the fine-scale differences in ancestry within and across the United States and informs our understanding of the relationship between racial and ethnic identities and genetic ancestry.” – see also: The Fluidity of Race from greg cochran.

Genghis Khan’s genetic legacy has competition“The Mongolian leader left a strong footprint in the Y chromosomes of modern descendants — but he was not the only one.”

Largest-ever autism genome study finds most siblings have different autism-risk genes“In the new study, Dr. Scherer’s team sequenced 340 whole genomes from 85 families, each with two children affected by autism. The majority of siblings (69 percent) had little to no overlap in the gene variations known to contribute to autism. They found that the sibling pairs shared the same autism-associated gene changes less than one third of the time (31 percent). The findings challenge long-held presumptions. Because autism often runs in families, experts had assumed that siblings with the disorder were inheriting the same autism-predisposing genes from their parents. It now appears this may not be true.” – h/t shrikant mantri!

Genetic mutation for metabolic disease identified within an Inuit population“The disease in question, glycogen storage disease type IIIa, is caused by mutations in the AGL gene, leading to less-active glycogen-debranching enzymes. The disorder disrupts the body’s capacity to release sugar from glycogen, resulting in the formation of damaging glycogen deposits…. Glycogen storage disease IIIa affects around one in 100,000 people in North America. However, the researchers estimate that the disorder may affect around 1 in 2,500 people in Nunavik – the homeland of the Inuit in Quebec.” – maybe they should stick to eating seal blubber. srsly!

Admixture in the Americas: Admixture among US Blacks and Hispanics and academic achievement“[W]e see the expected directions and order, for Blacks (who are mostly African), American admixture is positive and European is more positive…. We do not see the expected results per genetic model. Among Hispanics who are 73% European, African admixture has a positive relationship to academic achievement. American admixture is negatively correlated and European positively, but weaker than African. The only thing that’s in line with the genetic model is that European is positive. On the other hand, results are not in line with a null model either….” – from emil kirkegaard.

School“In summary, it very much looks like more years of education are associated with an increase in intelligence test scores, but not anything like as strongly to underlying general intelligence or to underlying basic processing speeds.” – from dr. james thompson.

Genetic Pleiotropy Explains Associations between Musical Auditory Discrimination and Intelligence“[A] large sample of Swedish twins (N = 10,500) was used to investigate the genetic architecture of the associations between intelligence and performance on three musical auditory discrimination tasks (rhythm, melody and pitch). Phenotypic correlations between the tasks ranged between 0.23 and 0.42 (Pearson r values). Genetic modelling showed that the covariation between the variables could be explained by shared genetic influences. Neither shared, nor non-shared environment had a significant effect on the associations. Good fit was obtained with a two-factor model where one underlying shared genetic factor explained all the covariation between the musical discrimination tasks and IQ, and a second genetic factor explained variance exclusively shared among the discrimination tasks. The results suggest that positive correlations among musical aptitudes result from both genes with broad effects on cognition, and genes with potentially more specific influences on auditory functions.” – h/t rosalind arden!

The Role of Parenting in the Prediction of Criminal Involvement: Findings From a Nationally Representative Sample of Youth and a Sample of Adopted Youth [pdf] – “The role of parenting in the development of criminal behavior has been the source of a vast amount of research, with the majority of studies detecting statistically significant associations between dimensions of parenting and measures of criminal involvement. An emerging group of scholars, however, has drawn attention to the methodological limitations — mainly genetic confounding — of the parental socialization literature. The current study addressed this limitation by analyzing a sample of adoptees to assess the association between 8 parenting measures and 4 criminal justice outcome measures. The results revealed very little evidence of parental socialization effects on criminal behavior before controlling for genetic confounding and no evidence of parental socialization effects on criminal involvement after controlling for genetic confounding.” – h/t jayman!

Hospitals Aim to Better Match Blood Donors and Recipients“People fall into one of four main blood groups — A, B, AB and O — and they have a so-called Rh factor that is either positive or negative. But scientists over the last few decades have discovered around 33 blood groups and continue to identify more. Each group also contains multiple variations that go to make up a patient’s exact blood type.”

Ageing research: Blood to blood“By splicing animals together, scientists have shown that young blood rejuvenates old tissues. Now, they are testing whether it works for humans.” – parabiosis. it’s baaaack!

Comparative analysis of the human saliva microbiome from different climate zones: Alaska, Germany, and Africa [pdf] – “Here we analyze the saliva microbiome from native Alaskans (76 individuals from 4 populations), Germans (10 individuals from 1 population), and Africans (66 individuals from 3 populations) based on next-generation sequencing of partial 16S rRNA gene sequences. After quality filtering, a total of 67,916 analyzed sequences resulted in 5,592 OTUs (defined at ≥97% identity) and 123 genera. The three human groups differed significantly by the degree of diversity between and within individuals (e.g. beta diversity: Africans > Alaskans > Germans; alpha diversity: Germans > Alaskans > Africans). UniFrac, network, ANOSIM, and correlation analyses all indicated more similarities in the saliva microbiome of native Alaskans and Germans than between either group and Africans. The native Alaskans and Germans also had the highest number of shared bacterial interactions.”

Tuberculosis genomes track human history“A study of nearly 5,000 samples of Mycobacterium tuberculosis from around the world shows how a lineage of the bacterium that emerged thousands of years ago in Asia has since become a global killer that is widely resistant to antibiotic drugs. Although M. tuberculosis probably first emerged some 40,000 years ago in Africa, the disease did not take hold until humans took to farming…. [T]he common ancestor of all the M. bacterium strains circulating today began spreading around 10,000 years ago in the ancient Fertile Crescent, a region stretching from Mesopotamia to the Nile Delta that was a cradle of agriculture…. But of all the M. bacterium strains circulating today, few strike more fear in public-health officials than the ‘Beijing lineage’. First identified in greater Beijing in the mid-1990s, this lineage now circulates throughout the world and many strains are resistant to drugs that vanquish other types of TB…. Consistent with its name, the Beijing lineage did indeed emerge near north-eastern China…. And it did so around 6,600 years ago, the researchers found, which coincides with archaeological evidence for the beginnings of rice farming in China’s upper Yangtze River valley.” – h/t billare!

Your Friends Know How Long You Will Live: A 75-Year Study of Peer-Rated Personality Traits“To test whether friends’ reports of personality predict mortality risk, we used data from a 75-year longitudinal study (the Kelly/Connolly Longitudinal Study on Personality and Aging). In that study, 600 participants were observed beginning in 1935 through 1938, when they were in their mid-20s, and continuing through 2013. Male participants seen by their friends as more conscientious and open lived longer, whereas friend-rated emotional stability and agreeableness were protective for women. Friends’ ratings were better predictors of longevity than were self-reports of personality, in part because friends’ ratings could be aggregated to provide a more reliable assessment.”

Voluntary Activities and Daily Happiness in the US [pdf] – “This paper analyzes differences in daily happiness between those individuals in the United States who perform voluntary activities during the day, and those who do not…. [T]hose who devote any time to voluntary activities during the day report higher levels of daily happiness than those who do not…. [W]hen the issue of reverse causality is taken into account, we find no differences in daily happiness between volunteers and non-volunteers, which indicates that happier individuals are also more likely to volunteer.” – h/t ben southwood!

Aberrant Gene Expression in Humans“The uniqueness of individuals is due to differences in the combination of genetic, epigenetic and environmental determinants. Understanding the genetic basis of phenotypic variation is a key objective in genetics…. One of our major findings is that private SNPs may contribute to aberrant expression in outlier individuals. These private SNPs are more frequently located in the enhancer and promoter regions of genes that are aberrantly expressed, suggesting a possible regulatory function of these SNPs.”

Recurrent loss of sex is associated with accumulation of deleterious mutations in Oenothera“Sexual reproduction is nearly universal among eukaryotes. Theory predicts that the rarity of asexual eukaryotic species is in part caused by accumulation of deleterious mutations and heightened extinction risk associated with suppressed recombination and segregation in asexual species. We tested this prediction with a large dataset of 62 transcriptomes from 29 species in the plant genus Oenothera, spanning 10 independent transitions between sexual and a functionally asexual genetic system called permanent translocation heterozygosity…. These results confirm that an important advantage of sex is that it facilitates selection against deleterious alleles, which might help to explain the dearth of extant asexual species.” – h/t melissa wilson sayres!

Perceptions Of Required Ability Act As A Proxy For Actual Required Ability In Explaining The Gender Gap – @slate star codex. make sure to read jayman’s comment there! this one, too.

Lewontin wins the Crafoord Prize“The Crafoord Prize for 2015 was awarded to Richard Lewontin and Tomoko Ohta, for their discovery that there was very much more genetic variation that had been expected. Lewontin discovered this using protein gel electrophoresis to study a number of loci in Drosophila. It’s an important result. The problem is, virtually everything he’s said and done since that time has been a pile of steaming ideological crap.” – from greg cochran.

Single Markers Tell You Only a Bit About Individual Ancestry“A new paper in The American Journal of Human Genetics, Estimates of Continental Ancestry Vary Widely among Individuals with the Same mtDNA Haplogroup, tells you something which should be obvious: one marker tells you only so much about individual ancestry. In other words, the history of one gene can only tell you so much about the whole genome. Because mtDNA and Y chromosome* does not recombine you can treat it as one long genetic marker…. But Richard Lewontin’s insight that a great deal of human genetic variation is not partitioned across populations, but within them, applies to mtDNA and the Y chromosomes as well. Where Lewontin’s insight misleads is that using just a few more markers one can obtain relatively robust phylogenetic trees which reflect well the population structure and history of a given species.” – also from razib.

The Economist takes a half step forwards“They do not examine the usual finding that educated parents are more influential than rich parents in supposedly ‘boosting’ intelligence. They leave out the genetic element entirely, and say it is ‘incomes’ which are inherited. If so adoption into a rich household should have massive effects on intellect, but that is not found. If adoption cannot wipe the slate clean, what chance a kindergarten?” – from dr. james thompson.

Gender divide in religious belief, survey suggests“A big gender divide exists between men and women in their 40s in belief in God and life after death, a poll suggests. Of the British men surveyed, 54% said they were atheists or agnostics compared with only 34% of women. The study also showed that Muslims in the survey had the fewest doubts about the existence of God and the afterlife. The research involving more than 9,000 British people born in 1970 was analysed at the University of Essex.” – h/t ed west! who tweeted: “71% of evangelical Christians have no doubts about God’s existence. 33% of Catholics, 16% of Anglicans & Methodists.”

This Woman Can’t Feel Fear“Damage from a rare genetic condition appears to have knocked out the ‘fear center’ in her brain.”

Thumb bones in pre-humans make them more like us, study says“Some of our tree-swinging pre-human ancestors may have been a bit more like us than previously thought, thanks to a tiny section of their thumbs. One key attribute that separates humans from other animals is our opposable thumb, and the way parts of the thumb are structured to allow for a strong yet precise grip that fostered advanced use of tools. It’s what allows us to throw items more precisely, pick guitars and turn a key. And now, thanks to high-tech tools of our own, scientists have determined that a couple million years ago one of our pre-human ancestors had the same human-defining precision grip, even though researchers think of them as little more than upright walking apes, according to a study published Thursday in the journal Science. That supports earlier but controversial evidence that the small-brained Australopithecus africanus fashioned early tools.” – h/t regular ron!

‘Designer babies’ debate should start, scientists say – h/t avi tuschman!

Darwin May Have Experienced Extreme Anxiety

Why Footbinding Persisted in China for a Millennium“Despite the pain, millions of Chinese women stood firm in their devotion to the tradition.”

Thomas Cromwell was the Islamic State of his day“No one can be sure of the exact figure, but it is estimated that the destruction started and legalised by Cromwell amounted to 97% of the English art then in existence. Statues were hacked down. Frescoes were smashed to bits. Mosaics were pulverized. Illuminated manuscripts were shredded. Wooden carvings were burned. Precious metalwork was melted down. Shrines were reduced to rubble.”

bonus: When it comes to speedy evolution, you can’t outpace this lizard’s penis

bonus bonus: FDA Considering Releasing Genetically-Modified Mosquitos In Florida – h/t sam bowman!

bonus bonus bonus: Fish Live Under Antarctica’s Ice Shelf, Where It Seems They Shouldn’t Survive“Biologists expected the seafloor under a glacier to be nearly barren, until life swam into view.”

bonus bonus bonus bonus: This fish lived in peace for 70 million years. Then it met the Army Corps of Engineers.

bonus bonus bonus bonus bonus: All in the (bigger) family“A decade of genetic data and other evidence has persuaded most researchers that insects and crustaceans, long considered widely separated branches of the arthropod family, actually belong together. The new arthropod tree puts hexapods — six-limbed creatures that include insects, springtails, and silverfish — as closer kin to crabs, lobster, shrimp, and crayfish than those ‘standard’ crustaceans are to others such as seed shrimp.”

(note: comments do not require an email. comparing apples and oranges.)

Zigzags on a Shell From Java Are the Oldest Human Engravings“The early human Homo erectus also made the oldest known shell tools half a million years ago.” — see also: The art of Homo erectus“What we can say is that these artifacts carry information about the capabilities of their makers. The few non-perishable marked objects also speak to the likely presence of design in perishable elements of material culture. Clothing, however rudimentary, was likely to have been decorated in some way. Wooden tools were also probably notched and zigzagged — as the occasional bone and ivory implements suggest. They lived for the first time in a world that they could change.” – from john hawks.

Genetic diversity of Sub-Saharan Africa revealed[T]he researchers also found that there were more genetic similarities across Africa than they had thought. Dr Sandhu said: ‘The diversity among populations is not as diverse as we expected it to be….’ The researchers found that many Africans have some Eurasian DNA within their genetic ancestry, which suggests that Eurasians migrated back into Africa many thousands of years after they first left. And several of the populations were descended from the Bantu, a group that spread across Africa about 5,000 years ago.” — see also: The African Genome Variation Project shapes medical genetics in Africa.

and here is dienekes on the above study: African Genome Variation project paper“In too many papers to count, decreasing genetic diversity from East Africa was taken as evidence of an origin of H. sapiens in that locality and its expansion from there to Eurasia. This ‘East Africa=cradle of mankind’ theory has, as far as I can tell, nothing really to stand on. Granted, the oldest anatomically modern human remains have been found in East Africa 200-150 thousand years ago. But, the fact that old sapiens have been found in East Africa and not elsewhere is easily explained by the excellent conditions for preservation (as opposed, e.g., deserts or rainforests of Africa or elsewhere), and by the extraordinary effort by palaeoanthropologists in that area. One also needs to overlook a century of physical anthropology that concluded that East Africa was a contact zone between Caucasoids and Sub-Saharan Africans. We now know that there is no deep lineage of humans in modern east Africans. Take out the Eurasian ancestry and only a paltry Fst=0.027 remains with other Sub-Saharan Africans, a fraction of the Fst between, say, Europeans and East Asians.”

Living African group discovered to be the most populous humans over the last 150,000 years“New genetic research reveals that a small group of hunter-gatherers now living in Southern Africa once was so large that it comprised the majority of living humans during most of the past 150,000 years. Only during the last 22,000 years have the other African ethnicities, including the ones giving rise to Europeans and Asians, become vastly most numerous…. ‘This and previous studies show that the Khoisan peoples and the rest of modern humanity shared their most recent common ancestor approximately 150,000 years ago, so it was entirely unexpected to find that this group apparently did not intermarry with non-Khoisan neighbors for many thousand years….'” — see also The Least Bottlenecked Humans of All from razib.

Ants, altruism and self sacrifice“It’s the selfishness of genes that makes us unselfish…. ‘Group selection’ has always been portrayed as a more politically correct idea, implying that there is an evolutionary tendency to general altruism in people. Gene selection has generally seemed to be more of a right-wing idea, in which individuals are at the mercy of the harsh calculus of the genes. Actually, this folk understanding is about as misleading as it can be. Society is not built on one-sided altruism but on mutually beneficial co-operation. Nearly all the kind things people do in the world are done in the name of enlightened self-interest. Think of the people who sold you coffee, drove your train, even wrote your newspaper today. They were paid to do so but they did things for you (and you for them). Likewise, gene selection clearly drives the evolution of a co-operative instinct in the human breast, and not just towards close kin.” – from matt ridley. — see also: E.O. Wilson’s The Social Conquest of Earth from jason collins. h/t billare!

Genetic Variation in Human DNA Replication Timing“Replication timing, a driver of locus-specific mutation rates, varies among humans…. Replication timing associates with common polymorphisms near replication origins….” – whoa.

Genetic and environmental exposures constrain epigenetic drift over the human life course – h/t casey brown! who tweeted: “Worth repeating: DNA methylation is more genetic than epigenetic.”

IQ is in the genes“How parents raise us has no impact on how smart we become, a new study finds.”

Link discovered between fathers’ criminal history and sons’ intelligence“Sons whose fathers have criminal records tend to have lower cognitive abilities than sons whose fathers have no criminal history, data from over 1 million Swedish men show. The research, conducted by scientists in Sweden and Finland, indicates that the link is not directly caused by fathers’ behavior but is instead explained by genetic factors that are shared by father and son.”

Are bright people normal?“‘We found no support for the genetic Discontinuity Hypothesis that nonadditive genetic variance is greater for high intelligence….'” – from dr. james thompson.

Booze culture may date back 10 million years say scientists“A new study suggests that primates may have begun drinking alchol 10 million years ago, as fermented fruit on the forest floor…. Experts at Santa Fe College in the US studied the gene ADH4 which produces an enzyme to break down alcohol in the body. It was hypothesised that the enzyme would not appear until the first alcohol was produced by early farmers. But scientists were amazed to find it 10 million years earlier, at the end of the Miocene epoch.” – (them’s *my* ancestors right there! (~_^) )

Psychiatry: End of the Road for “Endophenotypes”?“In a nutshell, the researchers ran seven different genetic studies to try to find the genetic basis of a total of seventeen neurobehavioural traits, also known as ‘endophenotypes’…. Essentially an endophenotype is some trait, which could be almost anything, which is supposed to be related to (or part of) a psychiatric disorder or symptom, but which is ‘closer to genetics’ or ‘more biologica’ than the disorder itself. Rather than thousands of genes all mixed together to determine the risk of a psychiatric disorder, each endophenotype might be controlled by only a handful of genes – which would thus be easier to find…. Over 89% of the searches came up null in this way; for eight of the seventeen traits, the researchers found no associated genes using *any* strategy.” – from neuroskeptic.

Unequal fates for maths superstars“The fates of US child prodigies of the 1970s reveal great accomplishments but strong gender differences…. [B]oth genders reported unusually high levels of satisfaction with their lives and careers. ‘It seems that both sexes got what they wanted from life, even if those things were somewhat different….'” – h/t charles! – see also: Sometimes men and women want different things from ben southwood.

Are Chinese babies more docile? – peter frost on the freedman studies.

Inferior Faunas – from greg cochran.

Transparency International’s Corruption Perceptions Index 2014 released this week.

Domestication and Human Evolution Symposium @getCARTA sessions now available to watch online.

Does evolution need a revolution? – from jerry coyne.

Experimentally induced innovations lead to persistent culture via conformity in wild birds – birds have culture.

A Magisterial Synthesis Of Apes And Human Evolution“[Russell H.] Tuttle’s tome is a grand synthesis of all the latest research and data about apes and their relation to us…. He believes that bipedalism preceded the development of the brain in early humans –and was likely something inherited from smaller apes already used to using their feet to move laterally along branches in trees. Although chimpanzees and bonobos are our closest relatives on the evolutionary tree, they do not represent in their own locomotion good proto-models of what led to human upright posture and walking.”

‘Superbugs’ Kill India’s Babies and Pose an Overseas Threat“A growing chorus of researchers say the evidence is now overwhelming that a significant share of the bacteria present in India — in its water, sewage, animals, soil and even its mothers — are immune to nearly all antibiotics.” – h/t razib!

The RNA World: molecular cooperation at the origins of life“The RNA World concept posits that there was a period of time in primitive Earth’s history — about 4 billion years ago — when the primary living substance was RNA or something chemically similar. In the past 50 years, this idea has gone from speculation to a prevailing idea. In this Review, we summarize the key logic behind the RNA World and describe some of the most important recent advances that have been made to support and expand this logic. We also discuss the ways in which molecular cooperation involving RNAs would facilitate the emergence and early evolution of life.”

Tool to edit DNA revolutionizing research in Boston area – CRISPR.

Thomas Docherty on academic freedom“Managerial fundamentalism has taken hold in universities, with scholars viewed as resources that must be controlled…. A creeping incremental assault on academic freedom threatens not just what can be spoken aloud, but also what it is permissible to think: thought itself is to be subjected to management, so that its critical power is neutered or constrained….”

The Dark Enlightenment for Newbies“So what is dark about the Dark Enlightenment? Absolutely nothing. The Dark Enlightenment only looks dark in contrast to the blinding (as in, it blinds you) optimism of flash in the pan of blank slate equalism. The things that the DE contend about human nature — that parents naturally favor their children, that sexual attraction is a biological phenomenon, that some people are naturally smarter than others — were all accepted as common sense for most or all of human history. It is the unrealistic utopianism of modern liberalism which is ridiculously absurd. The Dark Enlightenment might be better termed The Return to Normalcy. So the phrase “Dark Enlightenment” might not be the best, but it has received enough attention that I don’t think we should abandon it.” – very nice post from empedocles.

Tanzania evicting 40,000 people from homeland to make room for Dubai royal family“It will become a private hunting reserve” – =/ (i’m linking to salon!) – h/t john durant!

bonus: Why Some Mosquitoes Spread Malaria and Others Don’t“Sequencing the genomes of numerous Anopheles mosquito species from locations around the world has shown why some can carry and spread the deadly disease malaria while others don’t.” – h/t srikant mantri!

bonus bonus: Humpback Whales in the Arabian Sea Have Been Isolated for 70,000 Years

bonus bonus bonus: A diet to die for“One bird feasts on food that would leave most other animals stone dead.”

bonus bonus bonus bonus: Insect Swarms Go Critical“Scientists have found tantalizing evidence that diverse biological systems, including the human brain, gene expression networks, bird flocks, and fish schools, behave as though they are near the ‘critical point’ of a phase transition, like correlated spins in a magnet on the verge of ordering.” – h/t jayman!

bonus bonus bonus bonus bonus: Weird Physics Can Make an Invisible Cat Visible“These cat pictures are brought to you by quantum entanglement as discussed by Einstein and Schrödinger.”

bonus bonus bonus bonus bonus bonus: “The Feynman Lectures on Physics”, The Most Popular Physics Book Ever Written, Now Completely Online

bonus bonus bonus bonus bonus bonus bonus: Tette per la Scienza – boobies! (it really IS this time! (~_^) )

(note: comments do not require an email. quantum cats!)

look! another linkfest! (^_^)

Our Cats, Ourselves“Which brings us to the genome of one critical tame animal: ourselves, humans. The Nobel Prize-winning zoologist Konrad Z. Lorenz once suggested that humans were subject to the same dynamics of domestication. Our brain and body sizes peaked during the end of the last ice age, and declined with the spread of agriculture…. Our cultural flexibility and creativity since the end of the ice age have not freed humans from evolutionary forces, but have opened up novel and startling paths. Thinking of domestication as an evolutionary process that occurs through ‘artificial’ selection creates a false dichotomy of nurture and nature that plays into a conceit of human exceptionalism. In fact, the idea that we are apart from nature, that it is ours to tame and exploit, is an outmoded approach. A more useful interpretation is that over the past 10,000 years, humans fashioned their own ecosystem. We were part of a natural process that altered the landscape…. The same forces that reshaped the genomes of our domesticates also reshaped ours.” – from razib. in the new york times! (^_^)

Ancient Easter Islanders Interbred With Native Americans“According to the recent study conducted by geneticists, the ancient inhabitants of Easter Island met and interbred with Native Americans long before Westerners arrived…. The recent genetic study is published on Thursday in the Current Biology journal. According to the study, these ancient people had significant contact with Native Americans hundreds of years ago, before the westerners reached the Island in 1722…. The finding of the study suggests that the intermixing occurred 19 to 23 generations ago. The researchers said that the Polynesian people (Rapa Nui’s) are not believed to have started mixing with Europeans until much later, the 19th century. Malaspinas said the genetic ancestry of today’s Rapa Nui people is roughly 75% Polynesian, 15% European and 10% Native American.”

Barley fuelled farmers’ spread onto Tibetan plateau“Cold-tolerant crop enabled high-altitude agriculture some 3,600 years ago”

Faster than Fisher“[M]igration and conquest, must explain the wide distribution of many geographically widespread selective sweeps and partial sweeps. They were adaptive, all right, but expanded much faster than possible from purely local diffusion.” – from greg cochran.

The Germ of Laziness – also from greg cochran.

Putting IBD to Bed – from razib.

The Red Queen Model of Recombination Hotspots Evolution in the Light of Archaic and Modern Human Genomes – h/t mwpennell! who tweeted: “Recombination hotspots in humans appear to be young…evidence for Red Queen theory for evolution of recombination?”

Inclusive fitness and sexual conflict: How population structure can modulate the battle of the sexes – h/t rebecca sear!

Do Chinese people get bored less easily?“Advanced farming — intensive land use, task specialization, monoculture — has profoundly shaped East Asian societies, particularly China. This is particularly so for rice farming. Because the paddies need standing water, rice farmers must work collectively to build, dredge, and drain elaborate irrigation networks. Wheat farming, by comparison, requires no irrigation and only half as much work. Advanced farming seems to have favored a special package of predispositions and inclinations, including greater acceptance of monotony. This has been shown in two recent studies.” – from peter frost.

Culture and state boredom: A comparison between European Canadians and Chinese“European Canadians (vs. Chinese) are more likely to experience state boredom.” – h/t erwin schmidt!

Gender differences in preferences, choices, and outcomes: SMPY longitudinal study“The figures show significant gender differences in life and career preferences, which affect choices and outcomes *even after ability is controlled for*…. According to the results, SMPY men are more concerned with money, prestige, success, creating or inventing something with impact, etc. SMPY women prefer time and work flexibility, want to give back to the community, and are less comfortable advocating unpopular ideas. Some of these asymmetries are at the 0.5 SD level or greater.” – from steve hsu.

Are liberals and conservatives differently wired? – also from peter frost.

Detecting ‘polygenes’ using signals of polygenic selection. Tools for increasing the power of GWAS – from davide piffer who tweeted: “Watson and Venter’s genomes have higher frequency of intelligence polygenenes.”

Intelligence lost at 1.23 IQ points per decade“Michael Woodley of Menie spends much of his time tending his ancestral estate, pacing the linen-fold panelled rooms of the ancient house, warming his hands at the towering stone fireplace and meditating on the collapse of the aristocracy, the paucity of contemporary innovation and the lamentable and persistent downward drift of the national intellect. Now he sends me a barefoot runner with his latest manuscript, which I have read as the autumn mists creep across the Nadder valley, before penning this reply for the poor urchin to carry back to his master. Young Woodley avers that, not only are we going to hell in a handcart, but we are doing so at a pace which he can predict with some accuracy (1.23 IQ points per decade), composed as it is of two dysgenic effects: the dull have been reproducing with greater fecundity than the bright (.39), and increasing paternal age has increased the rate of deleterious mutations (.84).” – from dr. james thompson.

Gypsy intelligence – also from dr. james thompson.

Lower Body Symmetry and Running Performance in Elite Jamaican Track and Field Athletes – h/t keith laws! who tweeted: “More symmetrical knees & ankles in Elite Jamaican track and field athletes…Of course…”

Great Ape Origins of Personality Maturation and Sex Differences: A Study of Orangutans and Chimpanzees

The Case Against Early Cancer Detection“[C]ancer screening may harm more people than it helps.” – h/t jason collins!

In the U.S., Few Heavy Drinkers Are Actually Alcoholics“About 90 percent of people who drink excessively — more than eight drinks a week for women, 15 for men — are not alcohol dependent.” – h/t ray sawhill!

Genes tell new story: Alcohol in moderation only benefits 15% of population“An alcoholic beverage a day, especially wine, is widely believed to help keep heart disease risk low, but new research from the University of Gothenburg shows that only about 15% of the human population — those with a specific the form of the cholesteryl ester transfer protein (CETP) gene — actually gain this benefit from moderate alcohol consumption.”

The Real Roots of Midlife Crisis“What a growing body of research reveals about the biology of human happiness — and how to navigate the (temporary) slump in middle age.”

Despite its problems, the United States of America is still the best. Thing. Ever.“Other aspects of America’s story, though, seem less important now that the quest for racial equality has become almost a religious mission; this week I finally got around to watching the HBO series John Adams, which begins with the Massachusetts lawyer defending Captain Thomas Preston, the officer blamed for the Boston massacre. The mob wanted to avenge the deaths but, this being a colony where people passionately believed in their ancestral English liberties, ‘due process’ was followed – a term that dates back to the Parliament of Edward III but was obviously influenced by Clause 39 of the Magna Carta. Due process is what was followed in the Ferguson case, but maybe that’s just a boring old racist Anglo-Saxon idea that we can forget about now (grand juries are literally Anglo-Saxon, dating back to the reign of Ethelred II, or possibly the vibrant culturally-enriching Viking maniac King Canute).” – from ed west.

Children are not science projects“What do we tell to prospective adoptive parents? The first answer, and the only answer that ultimately counts, is that they are doing the Lord’s work. They have the opportunity to provide love and nurturing to a child who needs it. There are few better things that human beings can do with their time. The second answer is that they, like biological parents, are not miracle-workers. They will be unable to mold the child. Sometimes their adopted child will experience problems that are not the adoptive parents’ fault; sometimes they will reveal gifts of talent and character that are equally not to the adoptive parents’ credit. What is to the credit of good parents, adoptive and biological alike, is enfolding the child in love.” – from charles murray…who’s really just a big softie after all. (^_^) — see also: Adopt a child, but discard an illusion from dr. james thompson.

In Northern Ireland, a Wave of Immigrants Is Met With Fists – which came (or *should’ve* come) as a surprise to absolutely no one….

When exactly did the Industrial Revolution start?

Europe’s Bronze Age Collapse Not Caused by Climate Change

How Thanksgiving, the ‘Yankee Abolitionist Holiday,’ Won Over the South

Your Inner Feather“About 300 million years ago, our ancestors began to lay hard-shelled eggs. Those early animals would give rise to mammals, reptiles, and birds (collectively known as amniotes, named for the amniotic egg). Edwards and his colleagues found that the first amniotes already had the *entire* complement of feather patterning genes. That means you, as an amniote, have them too.” – cool!

Viruses as a Cure

Stop eating cats and dogs say animal rights campaigners in Switzerland“Cat appears on traditional Christmas menus in some areas of Switzerland.” – wait. what?!

bonus: Snakes are ‘righties’ — with their penis, that is

bonus bonus: Snakes Leave Identity Within Their Fang Marks“Getting a DNA swab from the fang marks of a snake bite can accurately identify the type of snake, a team working in Nepal has found.”

bonus bonus bonus: Monterey Bay researchers capture rare deep-sea anglerfish on video for first time – whoa!

bonus bonus bonus bonus: Ants Regularly Pack Up and Dig New Nests, and Nobody Knows Why

bonus bonus bonus bonus bonus: Red Baron’s WWI German Fokker triplane rebuilt by flying enthusiast – oooo! pretty. (^_^)

(note: comments do not require an email. a face only a mother could love. maybe.)


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