linkfest – 09/20/15

What Your DNA Says About Medieval History“A new study uses genetic data from living people to trace millennia-old migration patterns…. [M]uch of what Capelli and his colleagues discovered meshed with what historians already knew. For example, among northern Europeans, highest rate of admixing took place ‘around the late first millennium C.E., a time known to have involved significant upheaval in Europe,’ while admixture between north African and southern European populations was dated to a time span ‘consistent with migrations associated with the Arabic Conquest of the Iberian peninsula.’ But there were surprises, too. Most notably, Capelli and his colleagues discovered evidence for an influx of Mongolians into Europe that predated the reign of Ghengis Khan.” – orig. research article: The Role of Recent Admixture in Forming the Contemporary West Eurasian Genomic Landscape.

Inuit Study Adds Twist to Omega-3 Fatty Acids’ Health Story“A study published on Thursday in the journal Science reported that the ancestors of the Inuit evolved unique genetic adaptations for metabolizing omega-3s and other fatty acids. Those gene variants had drastic effects on Inuit’s bodies, reducing their heights and weights. Rasmus Nielsen, a geneticist at the University of California, Berkeley, and an author of the new study, said that the discovery raised questions about whether omega-3 fats really were protective for everyone, despite decades of health advice. ‘The same diet may have different effects on different people,’ he said…. The researchers found several genetic variants at different locations in the genome that were unusually common in the Inuit, compared with people in Europe or China. Several of these variations occurred within a cluster of genes that direct construction of enzymes called fatty acid desaturases. (The genes are called FADS, for short….) Even more intriguing was the fact that one of these gene variants was present in almost every Inuit in the study. It is much less common in other populations: About a quarter of Chinese people have it, compared with just 2 percent of Europeans. Natural selection is the only known way this gene variant could have become so common in the Inuit. Dr. Nielsen said this adaptation might have arisen as long ago as 20,000 years, when the ancestors of the Inuit were living in the Beringia region, which straddles Alaska and Siberia…. The adaptation did more than just change blood levels of fatty acids, the scientists found. Inuit who carried two copies of the variant gene were on average an inch shorter and 10 pounds lighter than those without a copy.” – orig. research article: Greenlandic Inuit show genetic signatures of diet and climate adaptation. see also Your Genes Are What You Eat from razib.

Height-reducing variants and selection for short stature in Sardinia“[K]nown height-decreasing alleles are at systematically higher frequencies in Sardinians than would be expected by genetic drift. The findings are consistent with selection for shorter stature in Sardinia and a suggestive human example of the proposed ‘island effect’ reducing the size of large mammals.” – h/t andrew sabisky!

Are humans still evolving? Yes, both globally and locally. – from jerry coyne.

5 key facts about the nuclear DNA from Sima de los Huesos“If confirmed, the results will push back the H. sapiens-H. neanderthalensis ancestor beyond 400 KYA. Meyer suggested that the ancestors of H. sapiens could have diverged from the branch leading to neandertals and denisovans 550 K to 765 K years ago. It may be possible that H. sapiens evolved in western Eurasia and later migrated back into Africa. The fossils from Europe, Asia and Africa in the 400 Ka. period are physically very diverse and may represent multiple species, only one of which could be the ancestor of today’s humans. For example, Chris Stringer thinks it may be needed to look at Homo antecessor and not Homo heidelbergensis as our last common ancestor with neandertals.”

New DNA tests on ancient Denisovan people ‘shows them occupying Altai cave 170,000 years ago’“Prehistoric Siberians lived in Denisova Cave earlier than scientists realised – new claim based on state-of-the-art technology.” – h/t paleoanthropology!

Origins, admixture and founder lineages in European Roma“We found a set of founder lineages, present in the Roma and virtually absent in the non-Roma, for the maternal (H7, J1b3, J1c1, M18, M35b, M5a1, U3, and X2d) and paternal (I-P259, J-M92, and J-M67) genomes. This lineage classification allows us to identify extensive gene flow from non-Roma to Roma groups, whereas the opposite pattern, although not negligible, is substantially lower (up to 6.3%). Finally, the exact haplotype matching analysis of both uniparental lineages consistently points to a Northwestern origin of the proto-Roma population within the Indian subcontinent.”

Why I’m sceptical about the idea of genetically inherited trauma“A recent scientific paper claiming that the children of Holocaust survivors showed evidence of inherited stress was deeply flawed – here’s why.”

Population genetic differentiation of height and body mass index across Europe“Here we find that many independent loci contribute to population genetic differences in height and body mass index (BMI) in 9,416 individuals across 14 European countries.”

North-South divide, Japanese style – from dr. james thompson.

Genetics of IQ and lifespan and Genius? Avoid rare functional genes and Heritability of Specific Cognitive Abilities and Schizophrenia and cognitive decline and g for Latinos and White matter efficiency predicts women’s IQ, but not men’s – all also from dr. james thompson!

SNP hits on cognitive ability from 300k individuals – from steve hsu. h/t holtz!

Do smart girls postpone first sex? and Do women find bright men sexy? – and even MORE from dr. james thompson!! whew!

Green Arabia’s key role in human evolution“Scientists have been illuminating the vital role played by the Arabian Peninsula in humankind’s exodus from Africa. Far from being a desert, the region was once covered by lush vegetation and criss-crossed by rivers, providing rich hunting grounds for our ancestors.”

The UK10K project identifies rare variants in health and disease – h/t kevin mitchell!

Genetics of aggressive behavior: An overview – h/t brian boutwell!

Sons of the Soil, Migrants, and Civil War“In nearly a third of ethnic civil wars since 1945, the conflict develops between members of a regional ethnic group that considers itself to be the indigenous “sons of the soil” and recent migrants from other parts of the country.” – h/t whyvert!

It’s finally out: The big review paper on the lack of political diversity in social psychology“Psychologists have demonstrated the value of diversity – particularly diversity of viewpoints – for enhancing creativity, discovery, and problem solving. But one key type of viewpoint diversity is lacking in academic psychology in general and social psychology in particular: political diversity.” – from jonathan haidt.

The genetics of alcohol dependence: Twin and SNP-based heritability, and genome-wide association study based on AUDIT scores – h/t amir sariaslan!

Chronotype Associations with Depression and Anxiety Disorders in a Large Cohort Study – h/t emily deans! who tweeted: “‘Morning people’ less likely to be depressed in this large and relatively thorough observational study.” – (morning people depress me. (~_^) )

The Hormone That Bonds Humans to Dogs – h/t old whig! who tweeted: “Evolutionary change is faster than we think? Case study: oxytocin.”

Does the Gender of Offspring Affect Parental Political Orientation? – h/t ben southwood! who tweeted: “Studies on offspring gender & political orientation plagued by publication bias; actually there’s no relationship.”

Do Angry Birds Make for Angry Children? A Meta-Analysis of Video Game Influences on Children’s and Adolescents’ Aggression, Mental Health, Prosocial Behavior, and Academic Performance“Overall, results from 101 studies suggest that video game influences on increased aggression (r = .06), reduced prosocial behavior (r = .04), reduced academic performance (r = −.01), depressive symptoms (r = .04), and attention deficit symptoms (r = .03) are minimal.” – h/t joseph schwartz!

Ancient campfires show early population numbers [in australia]“ANU archaeologist Alan Williams used radio carbon dating technology to examine charcoal dates from more than 1000 prehistoric campfires and based on this he says populations appear to have increased steadily until 25,000 years ago…. After this initial increase, he says, population levels remained steady or even declined from 25,000 years ago, during the more arid Last Glacial Maximum (25,000 to 13,000 years ago) when temperatures were about ten degrees cooler…. Campfire numbers began to grow again 13,000 years ago when the northern wet season re-emerged.”

Aboriginal ‘memories’ of Australia’s coastline go back more than 7,000 years

History became legend, legend became myth: Crater Lake – h/t razib! who tweeted: “8,000 year old explosion preserved in folk memory of klamath indians?”

Ancient Script Spurs Rethinking of Historic ‘Backwater’“At a temple site in the Republic of Georgia, letters carved in stone could change the way we see the development of writing.”

bonus: Microbiologists Keep Finding Giant Viruses in Melting Permafrost

bonus bonus: Ancient Cats Drove Ancient Dogs to Extinction – woof? (O.O)

bonus bonus bonus: this year’s ig nobel mathematics prize went to the authors of The Case of Moulay Ismael – Fact or Fancy?“Textbooks on evolutionary psychology and biology cite the case of the Sharifian Emperor of Morocco, Moulay Ismael the Bloodthirsty (1672–1727) who was supposed to have sired 888 children. This example for male reproduction has been challenged and led to a still unresolved discussion. The scientific debate is shaped by assumptions about reproductive constraints which cannot be tested directly — and the figures used are sometimes arbitrary. Therefore we developed a computer simulation which tests how many copulations per day were necessary to reach the reported reproductive outcome…. The results indicate that Moulay Ismael could have achieved this high reproductive success. A comparison of the three conception models highlights the necessity to consider female sexual habits when assessing fertility across the cycle. We also show that the harem size needed is far smaller than the reported numbers.” (~_^)

and the tweet of the week!:

(note: comments do not require an email. moulay ismael the bloodthirsty!)


linkfest – 05/11/15

Deep-ocean microbe is closest living relative of complex cells“A new study indicates that plants, fungi, and animals are descendants of archaea, the group of single-celled organisms that includes Sulfolobus, a resident of hot springs.” – h/t bill barendse! – see also: New Loki Microbe Is Closest Relative To All Complex Life.

A Surprise for Evolution in Giant Tree of Life“Researchers build the world’s largest evolutionary tree and conclude that species arise because of chance mutations — not natural selection…. This controversial proposal stems from efforts by Hedges and collaborators to build the world’s most comprehensive tree of life — a chart plotting the connections among 50,000 species of Earth’s vast menagerie. Their analysis suggests that speciation is essentially random. No matter what the life form — plant or animal, insect or mammal — it takes about 2 million years for a new species to form. Random genetic events, not natural selection, play the main role in speciation.” – see also Was Charles Darwin Wrong About Speciation? from razib.

Genetic changes to basic developmental processes evolve more frequently than thought“Newly evolved genes can rapidly assume control over fundamental functions during early embryonic development. The findings suggest that evolutionary changes to the genetics of fundamental biological processes occur more frequently than previously thought.” – h/t david bachinsky!

The First GMO Is 8,000 Years Old“Scientists find that bacteria modified DNA in sweet potatoes millennia ago.”

Behavioral idiosyncrasy reveals genetic control of phenotypic variability [pdf] – “If we could rear genetically identical individuals from a variety of genetic backgrounds and rear them in the same environment, how much phenotypic variation between individuals of the same genotype would we see? Would different genetic backgrounds differ in their degree of variability? What would account for these differences? We used Drosophila inbred lines to address these questions focusing on variability in locomotor handedness. We show that different genotypes vary dramatically in their propensity for variability, that phenotypic variability itself, as a trait, can be heritable, and that loci affecting variability can be mapped. The genetic control of variability has received little attention in quantitative genetics despite the important role variability plays in explaining phenotypic variation between individuals.”

two tweets from the Biology of Genomes meeting re. a presentation on mutation rates:

Team Characterizing DNA from Ancient Human with Recent Neanderthal Ancestry [registration req.] – see also Ancient DNA from an Upper Paleolithic European with recent Neanderthal ancestry“the male sample, Oase 1, is 37-42K years old and comes from the Pestera cu Oase site in southwestern Romania. it’s estimated to harbor 5-11% of genome-wide Neanderthal ancestry, with as much as 50% on chromosome 12. the admixture is in relatively long stretches, which suggests that the mixture took place four to six generations before Oase 1 was alive. – @the eurogenes blog.

The archaeology, chronology and stratigraphy of Madjedbebe (Malakunanja II): A site in northern Australia with early occupation“The stone artefacts and stratigraphic details support previous claims for human occupation 50–60 ka and show that human occupation during this time differed from later periods.” – h/t chris stringer!

Stone bracelet is oldest ever found in the world“Dating back 40,000 years to the Denisovan species of early humans, new pictures show beauty and craftsmanship of prehistoric jewellery.” – denisovan jewelry!!

The Old Race – from greg cochran.

Ancient DNA Tells a New Human Story“The study of ancient DNA has challenged this view. We now know that mass migrations occurred repeatedly, overwhelming natives while absorbing some of their genes…. Joseph Pickrell of Columbia University and David Reich of Harvard University argue that ‘major upheavals’ of human population have been ‘overwriting’ the genetic history of the past 50,000 years. The result, they say, is that ‘present-day inhabitants of many places in the world are rarely related in a simple manner to the more ancient peoples of the same region.'” – from matt ridley.

2,500-year old Etruscans“All that can be said based on this is that they seem broadly southern European and not particularly Tuscan.” – from dienekes. – h/t anthropology tip!

The time and place of European gene flow into Ashkenazi Jews – @the eurogenes blog.

Symbolic bones and interethnic violence in a frontier zone, northwest Mexico, ca. 500–900 C.E.“Persistent interethnic violence has affected some global regions for centuries…. In the prehispanic Northern Frontier of Mesoamerica, approximately 500–900 C.E., people of different ethnic backgrounds struggled for standing in a shifting sociopolitical landscape. Evidence is consistent with long-term social violence….” – h/t gaetan burgio!

London Conference on Intelligence 2015 Keynote – from dr. james thompson.

NIH bans funding for genetic engineering of human embryos – (>.<)

Three hundred years of low non-paternity in a human population“Here we use this approach to investigate 1273 conceptions over a period of 330 years in 23 families of the Afrikaner population in South Africa. We use haplotype frequency and diversity and coalescent simulations to show that the male population did not undergo a severe bottleneck and that paternity exclusion rates are high for this population. The rate of cuckoldry in this Western population was 0.9% (95% confidence interval 0.4–1.5%), and we argue that given the current data on historical populations we have to conclude that, at least for Western human populations, cuckoldry rate is probably in the range of 1%.” – h/t debbie kennett!

Genius and autism may share genetic link, study finds“Child prodigies and their autistic family members may share a genetic link, according to findings published online for the April issue of Human Heredity.”

Immediate susceptibility to visual illusions after sight onset – h/t laura kelley!

The glass is half full *and* half empty: A population-representative twin study testing if optimism and pessimism are distinct systems“Here, we addressed these questions in a genetically informative sample of 852 pairs of twins. Distinct genetic influences on optimism and pessimism were found. Significant family-level environment effects also emerged, accounting for much of the negative relationship between optimism and pessimism, as well as a link to neuroticism. A general positive genetics factor exerted significant links among both personality and life-orientation traits. Both optimism bias and pessimism also showed genetic variance distinct from all effects of personality and from each other.” – h/t stuart ritchie!

Stanford researchers observe the moment when a mind is changed

Nature or nurture? Are sporting champions born to win? – h/t razib!

Menstrual Cycle Phase Does Not Predict Political Conservatism

Heritability of decisions and outcomes of public goods games

The kind of student you were in elementary school predicts mortality – h/t timothy bates!

The Mask of Sanity Revisited: Psychopathic Traits and Affective Mimicry – h/t claire lehmann! who tweeted: “People with psychopathy can produce highly convincing but fake expressions of feelings.”

Polygyny without wealth: popularity in gift games predicts polygyny in BaYaka Pygmies – h/t steve stewart williams!

The kin selection argument continues, with those denying its importance holding firm. They’re wrong. – from jerry coyne.

Behaviorism and the revival of antiracism – from peter frost.

Heterogeneity of long-history migration explains cultural differences in reports of emotional expressivity and the functions of smiles – hmmmm. really? – see also: What your smile says about where you’re from“If you come from a country of immigrants, you’re more likely to crack a friendly smile on the street. That’s the conclusion of a new study, which may explain why Americans beam more than their Chinese and Russian counterparts.”

Is reading to your kids “unfairly disadvantaging” others? – hahahahahaha! – h/t brian boutwell! who tweeted: “The nonsense that you can believe when you’re convinced that genes don’t matter.” – see also Is having a loving family an unfair advantage?

How uncommon is tickertaping? Prevalence and characteristics of seeing the words you hear – h/t kevin mitchell!

Peter Visscher: Genomics, Big Data, Medicine, and Complex Traits – @steve hsu’s.

Memes are Genes – from evolution theorist. (where do memes come from?) – h/t jayman!

How can our future Mars colonies be free of sexism and racism? – (>.<) #virtuesignalling – h/t ed west!

Paternity Case for a New Jersey Mother of Twins Bears Unexpected Results: Two Fathers – ruh roh!

After Nearly Claiming His Life, Ebola Lurked in a Doctor’s Eye“Before he contracted Ebola, Dr. Ian Crozier had two blue eyes. After he was told he was cured of the disease, his left eye turned green [temporarily].” – whoa.

How music evolves“Statistical analysis of music reveals the truth about its periods of revolution.” – h/t argumatronic!

The Medieval Roots of Our DIY Gun Culture“Forget 3-D printers. The first garage gunsmiths date back to the late Middle Ages.”

When Baltimore Shook With Anger, Here’s What China Saw“Online reaction revealed much about Chinese tension with an influx of African immigrants.” – h/t holtz!

No, there’s no “hate speech” exception to the First Amendment – duh. – from eugene volokh.

bonus: The migration of the eagle hunters – awesome!

(note: comments do not require an email. kazakh eagle hunter!)

linkfeast – 01/27/15

Human evolution tied to a small fraction of the genome“Only about 7.5 percent of the human genetic instruction book shaped the evolution of human traits, a new study suggests. And it’s often not genes, but the how-to instructions for using those genes that are most important, researchers report January 19 in Nature Genetics…. Previously, researchers have mostly looked for evolutionary clues in protein-producing genes because proteins do much of the important work in cells and organisms. Altering a protein may change the way an organism looks or acts. But mutations that alter proteins often are devastating to an organism and therefore aren’t passed on to offspring. Gulko and colleagues found that only 9 percent of the DNA that got evolution’s attention resides in protein-coding parts of the genome that are shared with other species. About 52 percent of the places showing signs of natural selection were in intergenic regions, the stretches of DNA between genes. Another 35 percent were in introns — spacer DNA found within genes but not involved in encoding proteins. Both intergenic regions and introns often contain DNA responsible for controlling gene activity. These findings suggest that human evolution works mostly through changes in how genes are used, rather than by altering genes and the proteins they encode.”

The Wrists of Birds Reveal Evolution Undoing Itself“Contrary to earlier claims, a new study shows that evolution may be reversible.” – previously from greg cochran: Back to the trees.

Kennewick Man was Native American“‘Genetic analysis is still under way in Denmark, but documents obtained through the federal Freedom of Information Act say preliminary results point to a Native-American heritage.'” – from dienekes. see also from razib: Native Americans Are Evolutionarily Elegant“One insight of modern ancient DNA is that there has been a great deal of population turnover over the past ~10,000 years, as well as admixture between disparate lineages. When Kennewick Man died ~9,000 years ago Europeans as we understand them did not exist genetically.”

The Genetic Ancestry of African Americans, Latinos, and European Americans across the United States“Over the past 500 years, North America has been the site of ongoing mixing of Native Americans, European settlers, and Africans (brought largely by the trans-Atlantic slave trade), shaping the early history of what became the United States. We studied the genetic ancestry of 5,269 self-described African Americans, 8,663 Latinos, and 148,789 European Americans who are 23andMe customers and show that the legacy of these historical interactions is visible in the genetic ancestry of present-day Americans. We document pervasive mixed ancestry and asymmetrical male and female ancestry contributions in all groups studied. We show that regional ancestry differences reflect historical events, such as early Spanish colonization, waves of immigration from many regions of Europe, and forced relocation of Native Americans within the US. This study sheds light on the fine-scale differences in ancestry within and across the United States and informs our understanding of the relationship between racial and ethnic identities and genetic ancestry.” – see also: The Fluidity of Race from greg cochran.

Genghis Khan’s genetic legacy has competition“The Mongolian leader left a strong footprint in the Y chromosomes of modern descendants — but he was not the only one.”

Largest-ever autism genome study finds most siblings have different autism-risk genes“In the new study, Dr. Scherer’s team sequenced 340 whole genomes from 85 families, each with two children affected by autism. The majority of siblings (69 percent) had little to no overlap in the gene variations known to contribute to autism. They found that the sibling pairs shared the same autism-associated gene changes less than one third of the time (31 percent). The findings challenge long-held presumptions. Because autism often runs in families, experts had assumed that siblings with the disorder were inheriting the same autism-predisposing genes from their parents. It now appears this may not be true.” – h/t shrikant mantri!

Genetic mutation for metabolic disease identified within an Inuit population“The disease in question, glycogen storage disease type IIIa, is caused by mutations in the AGL gene, leading to less-active glycogen-debranching enzymes. The disorder disrupts the body’s capacity to release sugar from glycogen, resulting in the formation of damaging glycogen deposits…. Glycogen storage disease IIIa affects around one in 100,000 people in North America. However, the researchers estimate that the disorder may affect around 1 in 2,500 people in Nunavik – the homeland of the Inuit in Quebec.” – maybe they should stick to eating seal blubber. srsly!

Admixture in the Americas: Admixture among US Blacks and Hispanics and academic achievement“[W]e see the expected directions and order, for Blacks (who are mostly African), American admixture is positive and European is more positive…. We do not see the expected results per genetic model. Among Hispanics who are 73% European, African admixture has a positive relationship to academic achievement. American admixture is negatively correlated and European positively, but weaker than African. The only thing that’s in line with the genetic model is that European is positive. On the other hand, results are not in line with a null model either….” – from emil kirkegaard.

School“In summary, it very much looks like more years of education are associated with an increase in intelligence test scores, but not anything like as strongly to underlying general intelligence or to underlying basic processing speeds.” – from dr. james thompson.

Genetic Pleiotropy Explains Associations between Musical Auditory Discrimination and Intelligence“[A] large sample of Swedish twins (N = 10,500) was used to investigate the genetic architecture of the associations between intelligence and performance on three musical auditory discrimination tasks (rhythm, melody and pitch). Phenotypic correlations between the tasks ranged between 0.23 and 0.42 (Pearson r values). Genetic modelling showed that the covariation between the variables could be explained by shared genetic influences. Neither shared, nor non-shared environment had a significant effect on the associations. Good fit was obtained with a two-factor model where one underlying shared genetic factor explained all the covariation between the musical discrimination tasks and IQ, and a second genetic factor explained variance exclusively shared among the discrimination tasks. The results suggest that positive correlations among musical aptitudes result from both genes with broad effects on cognition, and genes with potentially more specific influences on auditory functions.” – h/t rosalind arden!

The Role of Parenting in the Prediction of Criminal Involvement: Findings From a Nationally Representative Sample of Youth and a Sample of Adopted Youth [pdf] – “The role of parenting in the development of criminal behavior has been the source of a vast amount of research, with the majority of studies detecting statistically significant associations between dimensions of parenting and measures of criminal involvement. An emerging group of scholars, however, has drawn attention to the methodological limitations — mainly genetic confounding — of the parental socialization literature. The current study addressed this limitation by analyzing a sample of adoptees to assess the association between 8 parenting measures and 4 criminal justice outcome measures. The results revealed very little evidence of parental socialization effects on criminal behavior before controlling for genetic confounding and no evidence of parental socialization effects on criminal involvement after controlling for genetic confounding.” – h/t jayman!

Hospitals Aim to Better Match Blood Donors and Recipients“People fall into one of four main blood groups — A, B, AB and O — and they have a so-called Rh factor that is either positive or negative. But scientists over the last few decades have discovered around 33 blood groups and continue to identify more. Each group also contains multiple variations that go to make up a patient’s exact blood type.”

Ageing research: Blood to blood“By splicing animals together, scientists have shown that young blood rejuvenates old tissues. Now, they are testing whether it works for humans.” – parabiosis. it’s baaaack!

Comparative analysis of the human saliva microbiome from different climate zones: Alaska, Germany, and Africa [pdf] – “Here we analyze the saliva microbiome from native Alaskans (76 individuals from 4 populations), Germans (10 individuals from 1 population), and Africans (66 individuals from 3 populations) based on next-generation sequencing of partial 16S rRNA gene sequences. After quality filtering, a total of 67,916 analyzed sequences resulted in 5,592 OTUs (defined at ≥97% identity) and 123 genera. The three human groups differed significantly by the degree of diversity between and within individuals (e.g. beta diversity: Africans > Alaskans > Germans; alpha diversity: Germans > Alaskans > Africans). UniFrac, network, ANOSIM, and correlation analyses all indicated more similarities in the saliva microbiome of native Alaskans and Germans than between either group and Africans. The native Alaskans and Germans also had the highest number of shared bacterial interactions.”

Tuberculosis genomes track human history“A study of nearly 5,000 samples of Mycobacterium tuberculosis from around the world shows how a lineage of the bacterium that emerged thousands of years ago in Asia has since become a global killer that is widely resistant to antibiotic drugs. Although M. tuberculosis probably first emerged some 40,000 years ago in Africa, the disease did not take hold until humans took to farming…. [T]he common ancestor of all the M. bacterium strains circulating today began spreading around 10,000 years ago in the ancient Fertile Crescent, a region stretching from Mesopotamia to the Nile Delta that was a cradle of agriculture…. But of all the M. bacterium strains circulating today, few strike more fear in public-health officials than the ‘Beijing lineage’. First identified in greater Beijing in the mid-1990s, this lineage now circulates throughout the world and many strains are resistant to drugs that vanquish other types of TB…. Consistent with its name, the Beijing lineage did indeed emerge near north-eastern China…. And it did so around 6,600 years ago, the researchers found, which coincides with archaeological evidence for the beginnings of rice farming in China’s upper Yangtze River valley.” – h/t billare!

Your Friends Know How Long You Will Live: A 75-Year Study of Peer-Rated Personality Traits“To test whether friends’ reports of personality predict mortality risk, we used data from a 75-year longitudinal study (the Kelly/Connolly Longitudinal Study on Personality and Aging). In that study, 600 participants were observed beginning in 1935 through 1938, when they were in their mid-20s, and continuing through 2013. Male participants seen by their friends as more conscientious and open lived longer, whereas friend-rated emotional stability and agreeableness were protective for women. Friends’ ratings were better predictors of longevity than were self-reports of personality, in part because friends’ ratings could be aggregated to provide a more reliable assessment.”

Voluntary Activities and Daily Happiness in the US [pdf] – “This paper analyzes differences in daily happiness between those individuals in the United States who perform voluntary activities during the day, and those who do not…. [T]hose who devote any time to voluntary activities during the day report higher levels of daily happiness than those who do not…. [W]hen the issue of reverse causality is taken into account, we find no differences in daily happiness between volunteers and non-volunteers, which indicates that happier individuals are also more likely to volunteer.” – h/t ben southwood!

Aberrant Gene Expression in Humans“The uniqueness of individuals is due to differences in the combination of genetic, epigenetic and environmental determinants. Understanding the genetic basis of phenotypic variation is a key objective in genetics…. One of our major findings is that private SNPs may contribute to aberrant expression in outlier individuals. These private SNPs are more frequently located in the enhancer and promoter regions of genes that are aberrantly expressed, suggesting a possible regulatory function of these SNPs.”

Recurrent loss of sex is associated with accumulation of deleterious mutations in Oenothera“Sexual reproduction is nearly universal among eukaryotes. Theory predicts that the rarity of asexual eukaryotic species is in part caused by accumulation of deleterious mutations and heightened extinction risk associated with suppressed recombination and segregation in asexual species. We tested this prediction with a large dataset of 62 transcriptomes from 29 species in the plant genus Oenothera, spanning 10 independent transitions between sexual and a functionally asexual genetic system called permanent translocation heterozygosity…. These results confirm that an important advantage of sex is that it facilitates selection against deleterious alleles, which might help to explain the dearth of extant asexual species.” – h/t melissa wilson sayres!

Perceptions Of Required Ability Act As A Proxy For Actual Required Ability In Explaining The Gender Gap – @slate star codex. make sure to read jayman’s comment there! this one, too.

Lewontin wins the Crafoord Prize“The Crafoord Prize for 2015 was awarded to Richard Lewontin and Tomoko Ohta, for their discovery that there was very much more genetic variation that had been expected. Lewontin discovered this using protein gel electrophoresis to study a number of loci in Drosophila. It’s an important result. The problem is, virtually everything he’s said and done since that time has been a pile of steaming ideological crap.” – from greg cochran.

Single Markers Tell You Only a Bit About Individual Ancestry“A new paper in The American Journal of Human Genetics, Estimates of Continental Ancestry Vary Widely among Individuals with the Same mtDNA Haplogroup, tells you something which should be obvious: one marker tells you only so much about individual ancestry. In other words, the history of one gene can only tell you so much about the whole genome. Because mtDNA and Y chromosome* does not recombine you can treat it as one long genetic marker…. But Richard Lewontin’s insight that a great deal of human genetic variation is not partitioned across populations, but within them, applies to mtDNA and the Y chromosomes as well. Where Lewontin’s insight misleads is that using just a few more markers one can obtain relatively robust phylogenetic trees which reflect well the population structure and history of a given species.” – also from razib.

The Economist takes a half step forwards“They do not examine the usual finding that educated parents are more influential than rich parents in supposedly ‘boosting’ intelligence. They leave out the genetic element entirely, and say it is ‘incomes’ which are inherited. If so adoption into a rich household should have massive effects on intellect, but that is not found. If adoption cannot wipe the slate clean, what chance a kindergarten?” – from dr. james thompson.

Gender divide in religious belief, survey suggests“A big gender divide exists between men and women in their 40s in belief in God and life after death, a poll suggests. Of the British men surveyed, 54% said they were atheists or agnostics compared with only 34% of women. The study also showed that Muslims in the survey had the fewest doubts about the existence of God and the afterlife. The research involving more than 9,000 British people born in 1970 was analysed at the University of Essex.” – h/t ed west! who tweeted: “71% of evangelical Christians have no doubts about God’s existence. 33% of Catholics, 16% of Anglicans & Methodists.”

This Woman Can’t Feel Fear“Damage from a rare genetic condition appears to have knocked out the ‘fear center’ in her brain.”

Thumb bones in pre-humans make them more like us, study says“Some of our tree-swinging pre-human ancestors may have been a bit more like us than previously thought, thanks to a tiny section of their thumbs. One key attribute that separates humans from other animals is our opposable thumb, and the way parts of the thumb are structured to allow for a strong yet precise grip that fostered advanced use of tools. It’s what allows us to throw items more precisely, pick guitars and turn a key. And now, thanks to high-tech tools of our own, scientists have determined that a couple million years ago one of our pre-human ancestors had the same human-defining precision grip, even though researchers think of them as little more than upright walking apes, according to a study published Thursday in the journal Science. That supports earlier but controversial evidence that the small-brained Australopithecus africanus fashioned early tools.” – h/t regular ron!

‘Designer babies’ debate should start, scientists say – h/t avi tuschman!

Darwin May Have Experienced Extreme Anxiety

Why Footbinding Persisted in China for a Millennium“Despite the pain, millions of Chinese women stood firm in their devotion to the tradition.”

Thomas Cromwell was the Islamic State of his day“No one can be sure of the exact figure, but it is estimated that the destruction started and legalised by Cromwell amounted to 97% of the English art then in existence. Statues were hacked down. Frescoes were smashed to bits. Mosaics were pulverized. Illuminated manuscripts were shredded. Wooden carvings were burned. Precious metalwork was melted down. Shrines were reduced to rubble.”

bonus: When it comes to speedy evolution, you can’t outpace this lizard’s penis

bonus bonus: FDA Considering Releasing Genetically-Modified Mosquitos In Florida – h/t sam bowman!

bonus bonus bonus: Fish Live Under Antarctica’s Ice Shelf, Where It Seems They Shouldn’t Survive“Biologists expected the seafloor under a glacier to be nearly barren, until life swam into view.”

bonus bonus bonus bonus: This fish lived in peace for 70 million years. Then it met the Army Corps of Engineers.

bonus bonus bonus bonus bonus: All in the (bigger) family“A decade of genetic data and other evidence has persuaded most researchers that insects and crustaceans, long considered widely separated branches of the arthropod family, actually belong together. The new arthropod tree puts hexapods — six-limbed creatures that include insects, springtails, and silverfish — as closer kin to crabs, lobster, shrimp, and crayfish than those ‘standard’ crustaceans are to others such as seed shrimp.”

(note: comments do not require an email. comparing apples and oranges.)

linkfest – 09/28/14

Europeans drawn from three ancient “tribes”“The modern European gene pool was formed when three ancient populations mixed within the last 7,000 years, Nature journal reports. Blue-eyed, swarthy hunters mingled with brown-eyed, pale skinned farmers as the latter swept into Europe from the Near East. But another, mysterious population with Siberian affinities also contributed to the genetic landscape of the continent.” – see also: Before Slavery“From what I can see so far, it looks as the invaders killed all the LBK-descended farmers in northern Europe, or nearly so. The locals had had long trapezoidal houses clustered in small villages: the Corded Ware culture has almost no buildings at all, and a lot less agriculture. They didn’t make the EEF guys serfs and get a cut of their grain – the villages disappeared. They didn’t tax them, but then money and bureaucracy hadn’t been invented yet. Same for slavery: hadn’t been invented, probably. Judging from the mtDNA patterns, they didn’t even grab many of the nubile women. The genetic mix changes little as you move across the north European plain: if the invaders were picking up local genes as they rolled along, it should have. We used to call Corded Ware the Battle-Axe culture, but that’s too accurate for comfort.” – from greg cochran.

They weren’t wimps: how modern humans, like Neanderthals, braved the northern cold“Recent finds at Willendorf in Austria reveal that modern humans were living in cool steppe-like conditions some 43,500 years ago – and that their presence overlapped with that of Neanderthals for far longer than we thought.” – h/t mr. robert ford!

Stone Age groups made similar toolmaking breakthroughs“Different palaeolithic populations around the world might have developed a crucial toolmaking skill independently. This conclusion, based on the analysis of hundreds of artefacts from a recently excavated archaeological site in Armenia, weakens a long-held theory that Stone Age people in Eurasia learnt sophisticated techniques from migrating African tribes. The work is published in Science.”

Human paternal and maternal demographic histories: insights from high-resolution Y chromosome and mtDNA sequences“Comparisons of maternally-inherited mitochondrial DNA (mtDNA) and paternally-inherited non-recombining Y chromosome (NRY) variation have provided important insights into the impact of sex-biased processes (such as migration, residence pattern, and so on) on human genetic variation…. Our results confirm the controversial assertion that genetic differences between human populations on a global scale are bigger for the NRY than for mtDNA, although the differences are not as large as previously suggested. More importantly, we find substantial regional variation in patterns of mtDNA *versus* NRY variation.” – h/t juan fernández lópez! – see also: New analysis of human genetic history reveals female dominance – (heh. that was a nice twist on the story! (~_^) ) h/t frau katze!

23andMe mega-study on different American groups – @dienekes’. see also: The genetic ancestry of African, Latino, and European Americans across the United States.

Admixture in Latin America: Geographic Structure, Phenotypic Diversity and Self-Perception of Ancestry Based on 7,342 Individuals“We estimated individual ancestry proportions in a sample of 7,342 subjects ascertained in five countries (Brazil, Chile, Colombia, México and Perú). These individuals were also characterized for a range of physical appearance traits and for self-perception of ancestry. The geographic distribution of admixture proportions in this sample reveals extensive population structure, illustrating the continuing impact of demographic history on the genetic diversity of Latin America. Significant ancestry effects were detected for most phenotypes studied. However, ancestry generally explains only a modest proportion of total phenotypic variation. Genetically estimated and self-perceived ancestry correlate significantly, but certain physical attributes have a strong impact on self-perception and bias self-perception of ancestry relative to genetically estimated ancestry.” – see also razib: The Phenotypic and the Genotypic.

Ashkenazi Jewish population has distinctive, yet similar genomes“Post-population bottleneck, descendants of Eastern European Jews are all 30th-ish cousins…. Compared to genomes of modern Europeans—in this case, the genomes of 26 Flemish people—the Ashkenazi genomes have 47 percent more novel DNA differences per genome. These DNA variants, while novel, are population specific; sequence sharing, where two individuals have a set of the same variants, is eight percent more abundant among the Ashkenazi Jews than it is between the two populations or even among the Flemish genomes.” – h/t billare!

Why Did Civilization Lag in Africa? – from steve sailer.

Force of nature gave life its asymmetry“‘Left-handed’ electrons destroy certain organic molecules faster than their mirror versions.”

make sure not to miss jayman’s new Obesity Facts page. and give him some money, too! (^_^)

A fruitful encounter“Did the Christian doctrine of original sin create the guilt cultures of Northwest Europe? Or did the arrow of causality run the other way?” – from peter frost.

Review: G Is for Genes: The Impact of Genetics on Education and Achievement (Kathryn Asbury, Robert Plomin) – from emil kirkegaard.

The hereditarian hypothesis almost certainly true“Surely, there are huge benefits to being the first author to publish a study that almost conclusively disproves the genetic model for AA’s. Researchers with access to the data have a strong incitement to publish such a study. If the data supports the view, they have all the necessary means too. Since they haven’t published it, we can hence infer that the data does not support the politically favorable non-genetic conclusion, but instead the genetic model.” – also from emil kirkegaard.

Cognitive ability and party identity in the United States“[I]ndividuals who identify as Republican have slightly higher verbal intelligence than those who identify as Democrat…. [H]igher intelligence among classically liberal Republicans compensates for lower intelligence among socially conservative Republicans.” – the results suggest. – h/t stuart ritchie!

Lighter-skinned minorities are more likely to support Republicans

A study of the performance of Egyptian college students on the Advanced Progressive Matrices“The Egyptian raw scores were transformed to British IQ equivalents using the published 1992 British norms for the APM, on which the sample obtained a British IQ of 89.5. Science students obtained a significantly higher average mean score than arts students by 7.5 IQ points. Male students obtained a non-significantly higher average IQ than female students 1.2 IQ points. Male students had greater variability than the female students.” – h/t erwin schmidt!

The Available Pool – ed realist goes all voldemort on us. again.

Epigenetics, the Glory and the Hype“Epigenetics is real. But it doesn’t change everything. That needs to be said, because people seem to get the impression that everything is changed.” – from razib.

Human preferences for sexually dimorphic faces may be evolutionarily novel [pdf] – “A large literature proposes that preferences for exaggerated sex typicality in human faces (masculinity/femininity) reflect a long evolutionary history of sexual and social selection. This proposal implies that dimorphism was important to judgments of attractiveness and personality in ancestral environments. It is difficult to evaluate, however, because most available data come from large-scale, industrialized, urban populations. Here, we report the results for 12 populations with very diverse levels of economic development. Surprisingly, preferences for exaggerated sex-specific traits are only found in the novel, highly developed environments. Similarly, perceptions that masculine males look aggressive increase strongly with development and, specifically, urbanization.” – h/t jayman!

Do your genes skew how you taste alcohol?“A new study shows that how people perceive and taste alcohol varies as a result of genetics. The scientists focused on three chemosensory genes—two bitter-taste receptor genes known as TAS2R13 and TAS2R38 and a burn receptor gene, TRPV1. The research is the first to consider whether variation in the burn receptor gene might influence alcohol sensations, which has not previously been linked to alcohol consumption.” – alcohol tastes gooooood! (~_^) – h/t phillip melton!

Parent–Offspring Similarity for Drinking: A Longitudinal Adoption Study [pdf] – “Findings imply that genetic influences on drinking behavior increase with age while shared family environment influences decline, especially during the transition from late-adolescence to early adulthood.” – h/t emil kirkegaard!

Violent Video Games and Real-World Violence: Rhetoric Versus Data“Contrary to the claims that violent video games are linked to aggressive assaults and homicides, no evidence was found to suggest that this medium was positively related to real-world violence in the United States. Unexpectedly, many of the results were suggestive of a decrease in violent crime in response to violent video games. Possible explanations for these unforeseen findings are discussed and researchers are cautioned about generalizing the results from laboratory and correlational studies to severe forms of violent behavior.” – h/t mugwump! who tweeted some of the tables here, here, and here.

The Objective Morality Delusion“Atheists often scorn those who believe in the God Delusion. The faithful, in turn, scorn those atheists who believe in the Objective Morality Delusion. The scorn is understandable in both cases, but I give the nod to the faithful on this one….” – from helian.

Paradox of nationalism“Nationalism as we know it arose in modern times in Europe. Other countries outside Europe just don’t seem to have the same thing, although there are exceptions, such as Japan, or maybe Turkey. And in fact, nationalism was at one time considered a part of liberalism – which is another European invention…. Other countries that don’t have the same history as Europe seem unlikely to develop that kind of nationalism. Think of Iraq, Syria, most African countries, even China: they are more given to clannishness than patriotism.” – from mr. mangan, esq.

Plant breeding, not working slaves harder, drove cotton efficiency gains in the US South – from pseudoerasmus.

Confusion Over the Biological Reality of the Human Races“[O]ne can see clearly why Wade’s argument is not racist: at the core of his argument is his claim that the tribalism of racial ethnocentrism belongs to an ancient stage of human evolution that has to be overcome to move into modern states and inclusive institutions (see Wade, 136, 173-82, 196-97).” – larry arnhart on A Troublesome Inheritance.

Yes, it’s official, men are from Mars and women from Venus, and here’s the science to prove it“In his fascinating new book the developmental biologist Lewis Wolpert argues that there is actually hard science behind many of our stereotypical gender roles.” – h/t claire lehmann!

The Woman’s Heart Attack“[M]en more typically have ‘crushing’ pain; women, nausea. That women are likelier to have early warning signs, such as unaccustomed fatigue or insomnia (unaccustomed: That’s the key word here). That we are likelier — this spooked me and kept me, for months, glued to calendars — to die within a year of a heart attack. That our symptoms can be so varied and nuanced that we feel no fear, seek no help, and possibly die — which may be why, although more men have heart attacks, a greater percentage of women die of them.”

The Evolution of Culturally-Variable Sex Differences: Men and Women Are Not Always Different, but When They Are…It Appears *Not* to Result from Patriarchy or Sex Role Socialization“[E]vidence is marshaled across 21 data sources that directly challenge this foundational assumption of social role theory. Empirically, sex differences in most psychological traits — in personality, sexuality, attitudes, emotions, behaviors, and cognitive abilities — are conspicuously *larger* in cultures with more egalitarian sex role socialization and greater sociopolitical gender equity. Even sex differences in many physical traits such as height, obesity, and blood pressure are larger in cultures with more egalitarian sex role socialization and greater sociopolitical gender equity.”

School Performance After Preterm Birth“An increased risk of poor school performance for children born preterm has been shown in many studies, but whether this increase is attributable to preterm birth per se or to other factors associated with preterm birth has not been resolved…. Preterm birth was strongly and negatively correlated with school performance. The distribution of school grades for children born at 31-33 weeks was on average 3.85 (95% confidence interval = -4.36 to -3.35) centiles lower than for children born at 40 weeks. For births at 22-24 weeks, the corresponding figure was -23.15 (-30.32 to -15.97). When taking confounders into account, the association remained. When restricting the analysis to siblings, however, the association between school performance and preterm birth after week 30 vanished completely, whereas it remained, less pronounced, for preterm birth before 30 weeks of gestation. Our study suggests that the association between school performance and preterm birth after 30 gestational weeks is attributable to factors other than preterm birth per se.”

Are Neighborhood Health Associations Causal? A 10-Year Prospective Cohort Study With Repeated Measurements – h/t amir sariaslan! who tweeted: “Neighborhoods did not cause health outcomes in Australian large longitudinal within-individual study over 10 years.”

Seat of Selflessness Found in Brains of Extreme Altruists“In this case researchers chose to study people who donated a kidney to a complete stranger. They found that not only are extreme altruists’ brains different from a normal person’s, they’re basically the opposite of a psychopath’s in one key way – indicating that a specific brain region may play an important role in people’s ability to care for one another.” – n=39, but it’s a start!

Can the Game of Thrones option save the UK?“The situation now resembles the Union of Crowns from 1603-1707 when Scotland had its own parliament but was still under the king in Westminster, and Cameron is behaving like Charles I: making promises to his northern kingdom that affect the southern one, without regards to how the southerners feel. Just as in 1640, the greatest protests are coming from the east of England, once the stronghold of Puritanism and the parliamentary rebels and now the Ukip heartland.” – from ed west.

God, Darwin and My College Biology Class“[A] third consequence of evolutionary insights: a powerful critique of theodicy, the scholarly effort to reconcile belief in an omnipresent, omni-benevolent God with the fact of unmerited suffering. Theological answers range from claiming that suffering provides the option of free will to announcing (as in the Book of Job) that God is so great and we so insignificant that we have no right to ask. But just a smidgen of biological insight makes it clear that, although the natural world can be marvelous, it is also filled with ethical horrors: predation, parasitism, fratricide, infanticide, disease, pain, old age and death — and that suffering (like joy) is built into the nature of things. The more we know of evolution, the more unavoidable is the conclusion that living things, including human beings, are produced by a natural, totally amoral process, with no indication of a benevolent, controlling creator.” – david barash, pessimist(?).

Incest a “fundamental right” says German committee says“Anti-incest laws in Germany could be scrapped after a government-backed group said relationships between brothers and sisters should be legal.” – those wacky germans! h/t anatoly!

Radicalised Muslims in UK more likely to be born in Britain, rich and depressed“Young British Muslims whose families have lived in the UK for generations are more at risk of radicalisation than recent migrants to Britain, according to new research which reveals the common characteristics of those most vulnerable to recruitment by terrorists.” – we’ve seen that pattern before. h/t ed west!

Millions of Old Tyres are Dumped Near Empty Apartment Blocks in Spanish Ghost Town – you HAVE to see the photos! h/t ian geldard!

bonus: Skin coloring of rhesus macaque monkeys linked to breeding success, new study shows

bonus bonus: Fantastically Wrong: Europe’s Insane History of Putting Animals on Trial and Executing Them – h/t kyle hill!

bonus bonus bonus: Belgium to build beer pipeline under Bruges – those wacky belgians!

(note: comments do not require an email. guilty!)